Development of a green, concise synthesis of nicotinamide derivatives catalysed by Novozym® 435 from Candida antarctica in sustainable continuous-flow microreactors

A continuous production of nicotinamide derivatives was performed for the first time by exploiting the continuous-flow microreactors coupled with enzymes.

Bibliographic Details
Published in:RSC Advances
Main Authors: Sheng, Zhi-Kai, Liu, Yi, Du, Li-Hua, Zhang, Shi-Yi, Zhang, Ao-Ying, Xie, Han-Jia, Lin, Hang, Yan, Bing-Lin, Xue, Miao-Miao, Ruan, Zhi-Xuan, Fu, Guo-Neng, Pan, Bing-Le, Zhou, Tong-Yao, Luo, Xi-Ping
Other Authors: Natural Science Foundation of Zhejiang Province, National Natural Science Foundation of China
Format: Article in Journal/Newspaper
Language:English
Published: Royal Society of Chemistry (RSC) 2024
Subjects:
Online Access:http://dx.doi.org/10.1039/d3ra07201k
http://pubs.rsc.org/en/content/articlepdf/2024/RA/D3RA07201K
Description
Summary:A continuous production of nicotinamide derivatives was performed for the first time by exploiting the continuous-flow microreactors coupled with enzymes.