Chemo- and regio-selective enzymatic lipophilisation of rutin, and physicochemical and antioxidant properties of rutin ester derivatives

Enzymatic acylation of the flavonoid disaccharide rutin was achieved using Candida antarctica lipase B. Lipophilicity of the rutin esters produced increased with increasing alkyl chain length, yet antioxidant properties were unaffected.

Bibliographic Details
Published in:RSC Advances
Main Authors: Mexia, Nikitia, Benohoud, Meryem, Rayner, Christopher M., Blackburn, Richard S.
Other Authors: Biotechnology and Biological Sciences Research Council
Format: Article in Journal/Newspaper
Language:English
Published: Royal Society of Chemistry (RSC) 2023
Subjects:
Online Access:http://dx.doi.org/10.1039/d3ra06333j
http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA06333J
Description
Summary:Enzymatic acylation of the flavonoid disaccharide rutin was achieved using Candida antarctica lipase B. Lipophilicity of the rutin esters produced increased with increasing alkyl chain length, yet antioxidant properties were unaffected.