Synthesis of 6′-galactosyllactose, a deviant human milk oligosaccharide, with the aid of Candida antarctica lipase-B

Using Novozyme N435 in organic media led to selective deacetylation of various pyranose saccharides. Two of the products were then used to synthesise 6'-galactosyllactose in overall a short pathway.

Bibliographic Details
Published in:	Organic & Biomolecular Chemistry
Main Authors:	Hunt, Kaarel Erik, García-Sosa, Alfonso T., Shalima, Tatsiana, Maran, Uko, Vilu, Raivo, Kanger, Tõnis
Other Authors:	European Regional Development Fund, Haridus- ja Teadusministeerium, Eesti Teaduste Akadeemia
Format:	Article in Journal/Newspaper
Language:	English
Published:	Royal Society of Chemistry (RSC) 2022
Subjects:	Antarc* Antarctica
Online Access:	http://dx.doi.org/10.1039/d2ob00550f http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00550F

Description
Summary:	Using Novozyme N435 in organic media led to selective deacetylation of various pyranose saccharides. Two of the products were then used to synthesise 6'-galactosyllactose in overall a short pathway.