Inhibitory effects of Atlantic cod ( Gadus morhua) peptides on RANKL-induced osteoclastogenesis in vitro and osteoporosis in ovariectomized mice
Gadus morhua inhibited RANKL-induced osteoclast formation by inhibiting the activation of MAPK and NF-κB pathways and reduced the bone loss caused by estrogen deficiency in OVX-mice, showing potential anti-osteoporosis activity.
Published in: | Food & Function |
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Main Authors: | , , , , , , |
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Royal Society of Chemistry (RSC)
2022
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Subjects: | |
Online Access: | http://dx.doi.org/10.1039/d1fo03696c http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO03696C |
Summary: | Gadus morhua inhibited RANKL-induced osteoclast formation by inhibiting the activation of MAPK and NF-κB pathways and reduced the bone loss caused by estrogen deficiency in OVX-mice, showing potential anti-osteoporosis activity. |
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