Fucoidans from Cucumaria frondosa ameliorate renal interstitial fibrosis via inhibition of the PI3K/Akt/NF-κB signaling pathway

The effects of Cucumaria frondosa polysaccharides (CFP) on renal interstitial fibrosis by regulating the PI3K/AKT/NF-κB signaling pathway were investigated in vivo and in vitro in this research.

Bibliographic Details
Published in:Food & Function
Main Authors: Song, Zhuoyue, Zhu, Mengru, Wu, Jun, Yu, Tian, Chen, Yao, Ye, Xianying, Li, Shijie, Xu, Nenggui
Other Authors: National Natural Science Foundation of China, Basic and Applied Basic Research Foundation of Guangdong Province, Natural Science Foundation of Shandong Province
Format: Article in Journal/Newspaper
Language:English
Published: Royal Society of Chemistry (RSC) 2022
Subjects:
Online Access:http://dx.doi.org/10.1039/d1fo03067a
http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO03067A
Description
Summary:The effects of Cucumaria frondosa polysaccharides (CFP) on renal interstitial fibrosis by regulating the PI3K/AKT/NF-κB signaling pathway were investigated in vivo and in vitro in this research.