A novel anticoagulant peptide discovered from Crassostrea gigas by combining bioinformatics with the enzymolysis strategy: inhibitory kinetics and mechanisms

A novel anticoagulant peptide (IEELEEELEAER) derived from Crassostrea gigas inhibits the clotting activity and delays thrombin generation in normal plasma by inhibiting thrombin activity and activation mainly.

Bibliographic Details
Published in:Food & Function
Main Authors: Cheng, Shuzhen, Wu, Di, Liu, Hanxiong, Xu, Xianbing, Zhu, Beiwei, Du, Ming
Other Authors: National Natural Science Foundation of China
Format: Article in Journal/Newspaper
Language:English
Published: Royal Society of Chemistry (RSC) 2021
Subjects:
Crassostrea gigas
Online Access:http://dx.doi.org/10.1039/d1fo02148f
http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO02148F
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spelling crroyalschem:10.1039/d1fo02148f 2024-05-19T07:39:08+00:00 A novel anticoagulant peptide discovered from Crassostrea gigas by combining bioinformatics with the enzymolysis strategy: inhibitory kinetics and mechanisms Cheng, Shuzhen Wu, Di Liu, Hanxiong Xu, Xianbing Zhu, Beiwei Du, Ming National Natural Science Foundation of China 2021 http://dx.doi.org/10.1039/d1fo02148f http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO02148F en eng Royal Society of Chemistry (RSC) http://rsc.li/journals-terms-of-use Food & Function volume 12, issue 20, page 10136-10146 ISSN 2042-6496 2042-650X journal-article 2021 crroyalschem https://doi.org/10.1039/d1fo02148f 2024-04-25T08:02:21Z A novel anticoagulant peptide (IEELEEELEAER) derived from Crassostrea gigas inhibits the clotting activity and delays thrombin generation in normal plasma by inhibiting thrombin activity and activation mainly. Article in Journal/Newspaper Crassostrea gigas Royal Society of Chemistry Food & Function
institution Open Polar
collection Royal Society of Chemistry
op_collection_id crroyalschem
language English
description A novel anticoagulant peptide (IEELEEELEAER) derived from Crassostrea gigas inhibits the clotting activity and delays thrombin generation in normal plasma by inhibiting thrombin activity and activation mainly.
author2 National Natural Science Foundation of China
format Article in Journal/Newspaper
author Cheng, Shuzhen
Wu, Di
Liu, Hanxiong
Xu, Xianbing
Zhu, Beiwei
Du, Ming
spellingShingle Cheng, Shuzhen
Wu, Di
Liu, Hanxiong
Xu, Xianbing
Zhu, Beiwei
Du, Ming
A novel anticoagulant peptide discovered from Crassostrea gigas by combining bioinformatics with the enzymolysis strategy: inhibitory kinetics and mechanisms
author_facet Cheng, Shuzhen
Wu, Di
Liu, Hanxiong
Xu, Xianbing
Zhu, Beiwei
Du, Ming
author_sort Cheng, Shuzhen
title A novel anticoagulant peptide discovered from Crassostrea gigas by combining bioinformatics with the enzymolysis strategy: inhibitory kinetics and mechanisms
title_short A novel anticoagulant peptide discovered from Crassostrea gigas by combining bioinformatics with the enzymolysis strategy: inhibitory kinetics and mechanisms
title_full A novel anticoagulant peptide discovered from Crassostrea gigas by combining bioinformatics with the enzymolysis strategy: inhibitory kinetics and mechanisms
title_fullStr A novel anticoagulant peptide discovered from Crassostrea gigas by combining bioinformatics with the enzymolysis strategy: inhibitory kinetics and mechanisms
title_full_unstemmed A novel anticoagulant peptide discovered from Crassostrea gigas by combining bioinformatics with the enzymolysis strategy: inhibitory kinetics and mechanisms
title_sort novel anticoagulant peptide discovered from crassostrea gigas by combining bioinformatics with the enzymolysis strategy: inhibitory kinetics and mechanisms
publisher Royal Society of Chemistry (RSC)
publishDate 2021
url http://dx.doi.org/10.1039/d1fo02148f
http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO02148F
genre Crassostrea gigas
genre_facet Crassostrea gigas
op_source Food & Function
volume 12, issue 20, page 10136-10146
ISSN 2042-6496 2042-650X
op_rights http://rsc.li/journals-terms-of-use
op_doi https://doi.org/10.1039/d1fo02148f
container_title Food & Function
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