A novel anticoagulant peptide discovered from Crassostrea gigas by combining bioinformatics with the enzymolysis strategy: inhibitory kinetics and mechanisms

A novel anticoagulant peptide (IEELEEELEAER) derived from Crassostrea gigas inhibits the clotting activity and delays thrombin generation in normal plasma by inhibiting thrombin activity and activation mainly.

Bibliographic Details
Published in:Food & Function
Main Authors: Cheng, Shuzhen, Wu, Di, Liu, Hanxiong, Xu, Xianbing, Zhu, Beiwei, Du, Ming
Other Authors: National Natural Science Foundation of China
Format: Article in Journal/Newspaper
Language:English
Published: Royal Society of Chemistry (RSC) 2021
Subjects:
Crassostrea gigas
Online Access:http://dx.doi.org/10.1039/d1fo02148f
http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO02148F
Description
Summary:A novel anticoagulant peptide (IEELEEELEAER) derived from Crassostrea gigas inhibits the clotting activity and delays thrombin generation in normal plasma by inhibiting thrombin activity and activation mainly.

Similar Items