INVESTIGATIONS ON THE MELANOPHORESTIMULATING HORMONES IN THE HYPOPHYSIS OF THE FINBACK WHALE (BALAENOPTERA PHYSALUS)
ABSTRACT Extracts of single hypophyses of the finback whale ( Balaenoptera physalus ) were exposed to zone electrophoresis on starch, and the electrophoretic samples tested for their melanophore-stimulating activity, using pieces of isolated skin of the lizard Anolis carolinensis in vitro as a test...
| Published in: | Acta Endocrinologica |
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| Main Authors: | , |
| Format: | Article in Journal/Newspaper |
| Language: | unknown |
| Published: |
Oxford University Press (OUP)
1967
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1530/acta.0.0560554 https://eje.bioscientifica.com/view/journals/eje/56/3/acta_56_3_022.xml |
| Summary: | ABSTRACT Extracts of single hypophyses of the finback whale ( Balaenoptera physalus ) were exposed to zone electrophoresis on starch, and the electrophoretic samples tested for their melanophore-stimulating activity, using pieces of isolated skin of the lizard Anolis carolinensis in vitro as a test object. It was demonstrated that four different components with melanophore-stimulating activities are present in a single whale hypophysis. The electrophoretic behaviour of three of these components are comparable to that of the MSH's of known chemical structures alpha-, beta-seryl-, and beta-glutamyl-MSH. The electrophoretic behaviour of a fourth component, differs from that of any of the known MSH's. This component is the most abundant – or has the strongest melanophore-stimulating activity – in comparison with the other components found in the whale. The possibility that this component is identical with the fat mobilizing factor discovered and isolated by Birk & Li (1963) is suggested. |
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