Addressing Exaggeration of Effects from Single RCTs

Abstract Randomised controlled trials are often presented as the gold standard for testing new medical treatments. In the early stages of research, however, reports from single trials are likely to show exaggerated effect estimates. Erik van Zwet, Simon Schwab and Sander Greenland explain why – and...

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Bibliographic Details
Published in:Significance
Main Authors: van Zwet, Erik, Schwab, Simon, Greenland, Sander
Format: Article in Journal/Newspaper
Language:English
Published: Oxford University Press (OUP) 2021
Subjects:
Greenland
Online Access:http://dx.doi.org/10.1111/1740-9713.01587
https://onlinelibrary.wiley.com/doi/pdf/10.1111/1740-9713.01587
https://onlinelibrary.wiley.com/doi/full-xml/10.1111/1740-9713.01587
https://academic.oup.com/jrssig/article-pdf/18/6/16/49188538/sign_18_6_16.pdf
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spelling croxfordunivpr:10.1111/1740-9713.01587 2024-09-30T14:35:45+00:00 Addressing Exaggeration of Effects from Single RCTs van Zwet, Erik Schwab, Simon Greenland, Sander 2021 http://dx.doi.org/10.1111/1740-9713.01587 https://onlinelibrary.wiley.com/doi/pdf/10.1111/1740-9713.01587 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/1740-9713.01587 https://academic.oup.com/jrssig/article-pdf/18/6/16/49188538/sign_18_6_16.pdf en eng Oxford University Press (OUP) https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model Significance volume 18, issue 6, page 16-21 ISSN 1740-9705 1740-9713 journal-article 2021 croxfordunivpr https://doi.org/10.1111/1740-9713.01587 2024-09-17T04:29:54Z Abstract Randomised controlled trials are often presented as the gold standard for testing new medical treatments. In the early stages of research, however, reports from single trials are likely to show exaggerated effect estimates. Erik van Zwet, Simon Schwab and Sander Greenland explain why – and propose a remedy Article in Journal/Newspaper Greenland Oxford University Press Greenland Significance 18 6 16 21
institution Open Polar
collection Oxford University Press
op_collection_id croxfordunivpr
language English
description Abstract Randomised controlled trials are often presented as the gold standard for testing new medical treatments. In the early stages of research, however, reports from single trials are likely to show exaggerated effect estimates. Erik van Zwet, Simon Schwab and Sander Greenland explain why – and propose a remedy
format Article in Journal/Newspaper
author van Zwet, Erik
Schwab, Simon
Greenland, Sander
spellingShingle van Zwet, Erik
Schwab, Simon
Greenland, Sander
Addressing Exaggeration of Effects from Single RCTs
author_facet van Zwet, Erik
Schwab, Simon
Greenland, Sander
author_sort van Zwet, Erik
title Addressing Exaggeration of Effects from Single RCTs
title_short Addressing Exaggeration of Effects from Single RCTs
title_full Addressing Exaggeration of Effects from Single RCTs
title_fullStr Addressing Exaggeration of Effects from Single RCTs
title_full_unstemmed Addressing Exaggeration of Effects from Single RCTs
title_sort addressing exaggeration of effects from single rcts
publisher Oxford University Press (OUP)
publishDate 2021
url http://dx.doi.org/10.1111/1740-9713.01587
https://onlinelibrary.wiley.com/doi/pdf/10.1111/1740-9713.01587
https://onlinelibrary.wiley.com/doi/full-xml/10.1111/1740-9713.01587
https://academic.oup.com/jrssig/article-pdf/18/6/16/49188538/sign_18_6_16.pdf
geographic Greenland
geographic_facet Greenland
genre Greenland
genre_facet Greenland
op_source Significance
volume 18, issue 6, page 16-21
ISSN 1740-9705 1740-9713
op_rights https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model
op_doi https://doi.org/10.1111/1740-9713.01587
container_title Significance
container_volume 18
container_issue 6
container_start_page 16
op_container_end_page 21
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