Time-dependent covariates

Abstract One of the main scientific advantages of conducting a longitudinal study is the ability to observe the temporal order of key exposure and outcome events. Specifically, we can determine whether changes in a covariate precede changes in the outcome of interest. Such data provide crucial evide...

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Bibliographic Details
Main Authors: Diggle, Peter J, Heagerty, Patrick J, Liang, Kung-yee., Zeger, Scott L
Format: Book Part
Language:unknown
Published: Oxford University PressOxford 2002
Subjects:
Online Access:http://dx.doi.org/10.1093/oso/9780198524847.003.0012
https://academic.oup.com/book/chapter-pdf/52446454/isbn-9780198524847-book-part-12.pdf
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Summary:Abstract One of the main scientific advantages of conducting a longitudinal study is the ability to observe the temporal order of key exposure and outcome events. Specifically, we can determine whether changes in a covariate precede changes in the outcome of interest. Such data provide crucial evidence for a causal role of the exposure (see Chapter 2 in Rothman and Greenland, 1998).