Novel cryoballoon ablation system for single shot pulmonary vein isolation: The prospective ICE-AGE-X Study
Abstract Funding Acknowledgements Type of funding sources: None. Background The arctic front cryoballon (AF-CB) provides effective and durable pulmonary vein isolation (PVI) associated with encouraging clinical outcome data. The POLARx cryoballoon incorporates unique features which may translate int...
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Online Access: | http://dx.doi.org/10.1093/europace/euab116.229 http://academic.oup.com/europace/article-pdf/23/Supplement_3/euab116.229/38130898/euab116.229.pdf |
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croxfordunivpr:10.1093/europace/euab116.229 2023-05-15T15:00:05+02:00 Novel cryoballoon ablation system for single shot pulmonary vein isolation: The prospective ICE-AGE-X Study Tilz, RRT Meyer-Saraei, RMS Vogler, JV Fink, TF Sciacca, VS Kirstein, BK Delgado Lopez, LDL Phan, HLP Traub, AT Keelani, AK Kuck, KHK Eitel, CE Heeger, CH 2021 http://dx.doi.org/10.1093/europace/euab116.229 http://academic.oup.com/europace/article-pdf/23/Supplement_3/euab116.229/38130898/euab116.229.pdf en eng Oxford University Press (OUP) https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model EP Europace volume 23, issue Supplement_3 ISSN 1099-5129 1532-2092 Physiology (medical) Cardiology and Cardiovascular Medicine journal-article 2021 croxfordunivpr https://doi.org/10.1093/europace/euab116.229 2022-04-15T06:27:49Z Abstract Funding Acknowledgements Type of funding sources: None. Background The arctic front cryoballon (AF-CB) provides effective and durable pulmonary vein isolation (PVI) associated with encouraging clinical outcome data. The POLARx cryoballoon incorporates unique features which may translate into improved efficacy and safety. Purpose To assess efficacy and safety of the novel POLARx cryoballoon in comparison to the fourth generation arctic front cryoballon (AF-CB4). Methods Twenty-five consecutive patients with paroxysmal or persistent atrial fibrillation (AF) were prospectively enrolled, underwent POLARx based PVI (POLARx group) and were compared to 25 consecutive patients treated with the fourth generation AF-CB (AF-CB4 group). Results A total of 100 (POLARx) and 97 (AF-CB4) pulmonary veins (PV) were identified and all PVs were successfully isolated utilizing the POLARx and AF-CB4, respectively. A significant difference regarding the mean minimal cryoballoon temperatures reached using the AF-CB4 and POLARx (-50 ± 6°C vs. -57 ± 7°C, p = 0.004) was observed. Real-time PVI was visualized in 81% of POLARx patients and 42% of AF-CB4 patients (p < 0.001). Despite a certain learning curve utilizing the POLARx a trend towards shorter median procedure time (POLARx: 45 (39, 53) minutes vs. AF-CB4: 55 (50, 60) minutes (p = 0.062) was found. No differences were observed for periprocedural complications. Conclusions The novel POLARx showed similar safety and efficacy compared to the AF-CB4. A higher rate of real-time electrical PV recordings and significantly lower balloon temperatures were observed using the POLARx as compared to AF-CB4. Article in Journal/Newspaper Arctic Oxford University Press (via Crossref) Arctic EP Europace 23 Supplement_3 |
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Open Polar |
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Oxford University Press (via Crossref) |
op_collection_id |
croxfordunivpr |
language |
English |
topic |
Physiology (medical) Cardiology and Cardiovascular Medicine |
spellingShingle |
Physiology (medical) Cardiology and Cardiovascular Medicine Tilz, RRT Meyer-Saraei, RMS Vogler, JV Fink, TF Sciacca, VS Kirstein, BK Delgado Lopez, LDL Phan, HLP Traub, AT Keelani, AK Kuck, KHK Eitel, CE Heeger, CH Novel cryoballoon ablation system for single shot pulmonary vein isolation: The prospective ICE-AGE-X Study |
topic_facet |
Physiology (medical) Cardiology and Cardiovascular Medicine |
description |
Abstract Funding Acknowledgements Type of funding sources: None. Background The arctic front cryoballon (AF-CB) provides effective and durable pulmonary vein isolation (PVI) associated with encouraging clinical outcome data. The POLARx cryoballoon incorporates unique features which may translate into improved efficacy and safety. Purpose To assess efficacy and safety of the novel POLARx cryoballoon in comparison to the fourth generation arctic front cryoballon (AF-CB4). Methods Twenty-five consecutive patients with paroxysmal or persistent atrial fibrillation (AF) were prospectively enrolled, underwent POLARx based PVI (POLARx group) and were compared to 25 consecutive patients treated with the fourth generation AF-CB (AF-CB4 group). Results A total of 100 (POLARx) and 97 (AF-CB4) pulmonary veins (PV) were identified and all PVs were successfully isolated utilizing the POLARx and AF-CB4, respectively. A significant difference regarding the mean minimal cryoballoon temperatures reached using the AF-CB4 and POLARx (-50 ± 6°C vs. -57 ± 7°C, p = 0.004) was observed. Real-time PVI was visualized in 81% of POLARx patients and 42% of AF-CB4 patients (p < 0.001). Despite a certain learning curve utilizing the POLARx a trend towards shorter median procedure time (POLARx: 45 (39, 53) minutes vs. AF-CB4: 55 (50, 60) minutes (p = 0.062) was found. No differences were observed for periprocedural complications. Conclusions The novel POLARx showed similar safety and efficacy compared to the AF-CB4. A higher rate of real-time electrical PV recordings and significantly lower balloon temperatures were observed using the POLARx as compared to AF-CB4. |
format |
Article in Journal/Newspaper |
author |
Tilz, RRT Meyer-Saraei, RMS Vogler, JV Fink, TF Sciacca, VS Kirstein, BK Delgado Lopez, LDL Phan, HLP Traub, AT Keelani, AK Kuck, KHK Eitel, CE Heeger, CH |
author_facet |
Tilz, RRT Meyer-Saraei, RMS Vogler, JV Fink, TF Sciacca, VS Kirstein, BK Delgado Lopez, LDL Phan, HLP Traub, AT Keelani, AK Kuck, KHK Eitel, CE Heeger, CH |
author_sort |
Tilz, RRT |
title |
Novel cryoballoon ablation system for single shot pulmonary vein isolation: The prospective ICE-AGE-X Study |
title_short |
Novel cryoballoon ablation system for single shot pulmonary vein isolation: The prospective ICE-AGE-X Study |
title_full |
Novel cryoballoon ablation system for single shot pulmonary vein isolation: The prospective ICE-AGE-X Study |
title_fullStr |
Novel cryoballoon ablation system for single shot pulmonary vein isolation: The prospective ICE-AGE-X Study |
title_full_unstemmed |
Novel cryoballoon ablation system for single shot pulmonary vein isolation: The prospective ICE-AGE-X Study |
title_sort |
novel cryoballoon ablation system for single shot pulmonary vein isolation: the prospective ice-age-x study |
publisher |
Oxford University Press (OUP) |
publishDate |
2021 |
url |
http://dx.doi.org/10.1093/europace/euab116.229 http://academic.oup.com/europace/article-pdf/23/Supplement_3/euab116.229/38130898/euab116.229.pdf |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
EP Europace volume 23, issue Supplement_3 ISSN 1099-5129 1532-2092 |
op_rights |
https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model |
op_doi |
https://doi.org/10.1093/europace/euab116.229 |
container_title |
EP Europace |
container_volume |
23 |
container_issue |
Supplement_3 |
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1766332191184257024 |