Lipase mediated synthesis of polycaprolactone and its silica nanohybrid
Abstract In this study, rice husk ash (RHA) silanized with 3-glycidyloxypropyl trimethoxysilane was used as support material to immobilize Candida antarctica lipase B. The developed biocatalyst was then utilized in the ring opening polymerization (ROP) of ε-caprolactone and in situ development of PC...
| Published in: | Pure and Applied Chemistry |
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| Main Authors: | , , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Walter de Gruyter GmbH
2019
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1515/pac-2018-1011 http://www.degruyter.com/view/j/pac.2019.91.issue-6/pac-2018-1011/pac-2018-1011.xml https://www.degruyter.com/document/doi/10.1515/pac-2018-1011/xml https://www.degruyter.com/document/doi/10.1515/pac-2018-1011/pdf |
| Summary: | Abstract In this study, rice husk ash (RHA) silanized with 3-glycidyloxypropyl trimethoxysilane was used as support material to immobilize Candida antarctica lipase B. The developed biocatalyst was then utilized in the ring opening polymerization (ROP) of ε-caprolactone and in situ development of PCL/Silica nanohybrid. The silanization degree of RHA was determined as 4 % (w) by thermal gravimetric analysis (TGA). Structural investigations and calculation of molecular weights of nanohybrids were realized by proton nuclear magnetic resonance ( 1 H NMR). Crystallinity was determined by differential scanning calorimetry (DSC) and X-ray diffraction (XRD). Scanning Electron Microscopy (SEM) was used for morphological observations. Accordingly, the PCL composition in the nanohybrid was determined as 4 %, approximately. Short chained amorphous PCL was synthesized with a number average molecular weight of 4400 g/mol and crystallinity degree of 23 %. In regards to these properties, synthesized PCL/RHA composite can find use biomedical applications. |
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