Causes for Ivermectin failure in Aptenodytes Forsteri

Ivermectin is an anti-helminthic drug that works on humans but not on penguins. This short perspective seeks to understand and offers an explanation to why Ivermectin is unsuccessful on penguins (other avian animals, such as eagles, and more), but has succeeded in the human population. The bioinform...

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Bibliographic Details
Main Author: Tabaee Damavandi, Pardis
Format: Other/Unknown Material
Language:unknown
Published: Center for Open Science 2021
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Online Access:http://dx.doi.org/10.31219/osf.io/ad9fx
Description
Summary:Ivermectin is an anti-helminthic drug that works on humans but not on penguins. This short perspective seeks to understand and offers an explanation to why Ivermectin is unsuccessful on penguins (other avian animals, such as eagles, and more), but has succeeded in the human population. The bioinformatics approach can lead to the potential design of novel derivatives that would be exclusively for veterinary use.