THE BIOSYNTHESIS OF 11-KETOTESTOSTERONE AND 11β-HYDROXYTESTOSTERONE BY ATLANTIC SALMON TISSUES IN VITRO
The in vitro synthesis of 11-ketotestosterone and 11β-hydroxytestosterone, from adrenosterone and testosterone, by gonadal and interrenal slices and by sperm was studied. The results establish that adrenosterone is the major precursor of 11-ketotestosterone in both interrenal and testicular tissue....
| Published in: | Canadian Journal of Biochemistry |
|---|---|
| Main Authors: | , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Canadian Science Publishing
1967
|
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1139/o67-067 http://www.nrcresearchpress.com/doi/pdf/10.1139/o67-067 |
| Summary: | The in vitro synthesis of 11-ketotestosterone and 11β-hydroxytestosterone, from adrenosterone and testosterone, by gonadal and interrenal slices and by sperm was studied. The results establish that adrenosterone is the major precursor of 11-ketotestosterone in both interrenal and testicular tissue. 11β-Hydroxytestosterone was synthesized mainly from testosterone by gonadal and interrenal tissue. The production of 11β-hydroxytestosterone by normal gonadal tissue is reported for the first time. |
|---|