Rabies virus strains circulating in Bhutan: implications for control

SUMMARY We report a molecular epidemiological study of rabies virus (RABV) strains circulating in animal populations in Bhutan, and investigate potential origins of these viruses. Twenty-three RABV isolates originating from dogs and other domestic animals were characterized by sequencing the partial...

Full description

Bibliographic Details
Published in:Epidemiology and Infection
Main Authors: TENZIN, WACHARAPLUESADEE, S., DENDUANGBORIPANT, J., DHAND, N. K., DORJI, R., TSHERING, D., RINZIN, K., RAIKA, V., DAHAL, N., WARD, M. P.
Format: Article in Journal/Newspaper
Language:English
Published: Cambridge University Press (CUP) 2010
Subjects:
Arctic
Indian
Online Access:http://dx.doi.org/10.1017/s0950268810002682
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0950268810002682
Description
Summary:SUMMARY We report a molecular epidemiological study of rabies virus (RABV) strains circulating in animal populations in Bhutan, and investigate potential origins of these viruses. Twenty-three RABV isolates originating from dogs and other domestic animals were characterized by sequencing the partial nucleoprotein (N) gene (395 bp). Phylogenetic analysis was conducted and the Bhutanese isolates were compared with rabies viruses originating from other parts of the world. Phylogenetic analysis showed that Bhutanese isolates were highly similar and were closely related to Indian strains and South Asian Arctic-like-1 viruses. Our study suggests that the rabies viruses spreading in southern parts of Bhutan have originated from a common ancestor, perhaps from the Indian virus strain.

Similar Items