Prevalence of serum IgG antibodies to Puumala virus (haemorrhagic fever with renal syndrome) in Northern Sweden

SUMMARY A stratified and randomly-selected population sample was identified in 1990 in order to study the seroprevalence of nephropathia epidemica (haemorrhagic fever with renal syndrome) in Northern Sweden. Sera from 1538 subjects (750 men, 788 women), 25—64 years of age, were analysed for the pres...

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Bibliographic Details
Published in:Epidemiology and Infection
Main Authors: Ahlm, C., Linderholm, M., Juto, P., Stegmayr, B., Settergren, B.
Format: Article in Journal/Newspaper
Language:English
Published: Cambridge University Press (CUP) 1994
Subjects:
Northern Sweden
Online Access:http://dx.doi.org/10.1017/s0950268800051542
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0950268800051542
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Summary:SUMMARY A stratified and randomly-selected population sample was identified in 1990 in order to study the seroprevalence of nephropathia epidemica (haemorrhagic fever with renal syndrome) in Northern Sweden. Sera from 1538 subjects (750 men, 788 women), 25—64 years of age, were analysed for the presence of Puumala virus (PUV) specific-IgG by the indirect immunofluorescence antibody test. Specific IgG was detected in sera from 83 subjects (5·4%). Men and women had similar seroprevalence rates. The highest seroprevalences were found in subjects 55 years or older (8·0%) and among farmers and forestry workers (15·9%). The geographic distribution of seropositive individuals was uneven and there were significantly more seropositive persons in rural than in urban areas (P < 0·05).

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