Endogenous biosynthesis of n-3 long-chain PUFA in Atlantic salmon
Abstract A more efficient utilisation of marine-derived sources of dietary n -3 long-chain PUFA ( n -3 LC PUFA) in cultured Atlantic salmon ( Salmo salar L.) could be achieved by nutritional strategies that maximise endogenous n -3 LC PUFA synthesis. The objective of the present study was to quantif...
Published in: | British Journal of Nutrition |
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Online Access: | http://dx.doi.org/10.1017/s0007114519000473 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0007114519000473 |
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crcambridgeupr:10.1017/s0007114519000473 2024-09-30T14:32:24+00:00 Endogenous biosynthesis of n-3 long-chain PUFA in Atlantic salmon Mock, Thomas S. Francis, David S. Jago, Matthew K. Glencross, Brett D. Smullen, Richard P. Turchini, Giovanni M. 2019 http://dx.doi.org/10.1017/s0007114519000473 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0007114519000473 en eng Cambridge University Press (CUP) https://www.cambridge.org/core/terms British Journal of Nutrition volume 121, issue 10, page 1108-1123 ISSN 0007-1145 1475-2662 journal-article 2019 crcambridgeupr https://doi.org/10.1017/s0007114519000473 2024-09-11T04:05:20Z Abstract A more efficient utilisation of marine-derived sources of dietary n -3 long-chain PUFA ( n -3 LC PUFA) in cultured Atlantic salmon ( Salmo salar L.) could be achieved by nutritional strategies that maximise endogenous n -3 LC PUFA synthesis. The objective of the present study was to quantify the extent of n -3 LC PUFA biosynthesis and the resultant effect on fillet nutritional quality in large fish. Four diets were manufactured, providing altered levels of dietary n -3 substrate, namely, 18 : 3 n -3, and end products, namely, 20 : 5 n -3 and 22 : 6 n -3. After 283 d of feeding, fish grew in excess of 3000 g and no differences in growth performance or biometrical parameters were recorded. An analysis of fatty acid composition and in vivo metabolism revealed that endogenous production of n -3 LC PUFA in fish fed a diet containing no added fish oil resulted in fillet levels of n -3 LC PUFA comparable with fish fed a diet with added fish oil. However, this result was not consistent among all treatments. Another major finding of this study was the presence of abundant dietary n -3 substrate, with the addition of dietary n -3 end product (i.e. fish oil) served to increase final fillet levels of n -3 LC PUFA. Specifically, preferential β -oxidation of dietary C 18 n -3 PUFA resulted in conservation of n -3 LC PUFA from catabolism. Ultimately, this study highlights the potential for endogenous synthesis of n -3 LC PUFA to, partially, support a substantial reduction in the amount of dietary fish oil in diets for Atlantic salmon reared in seawater. Article in Journal/Newspaper Atlantic salmon Salmo salar Cambridge University Press British Journal of Nutrition 121 10 1108 1123 |
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Open Polar |
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Cambridge University Press |
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crcambridgeupr |
language |
English |
description |
Abstract A more efficient utilisation of marine-derived sources of dietary n -3 long-chain PUFA ( n -3 LC PUFA) in cultured Atlantic salmon ( Salmo salar L.) could be achieved by nutritional strategies that maximise endogenous n -3 LC PUFA synthesis. The objective of the present study was to quantify the extent of n -3 LC PUFA biosynthesis and the resultant effect on fillet nutritional quality in large fish. Four diets were manufactured, providing altered levels of dietary n -3 substrate, namely, 18 : 3 n -3, and end products, namely, 20 : 5 n -3 and 22 : 6 n -3. After 283 d of feeding, fish grew in excess of 3000 g and no differences in growth performance or biometrical parameters were recorded. An analysis of fatty acid composition and in vivo metabolism revealed that endogenous production of n -3 LC PUFA in fish fed a diet containing no added fish oil resulted in fillet levels of n -3 LC PUFA comparable with fish fed a diet with added fish oil. However, this result was not consistent among all treatments. Another major finding of this study was the presence of abundant dietary n -3 substrate, with the addition of dietary n -3 end product (i.e. fish oil) served to increase final fillet levels of n -3 LC PUFA. Specifically, preferential β -oxidation of dietary C 18 n -3 PUFA resulted in conservation of n -3 LC PUFA from catabolism. Ultimately, this study highlights the potential for endogenous synthesis of n -3 LC PUFA to, partially, support a substantial reduction in the amount of dietary fish oil in diets for Atlantic salmon reared in seawater. |
format |
Article in Journal/Newspaper |
author |
Mock, Thomas S. Francis, David S. Jago, Matthew K. Glencross, Brett D. Smullen, Richard P. Turchini, Giovanni M. |
spellingShingle |
Mock, Thomas S. Francis, David S. Jago, Matthew K. Glencross, Brett D. Smullen, Richard P. Turchini, Giovanni M. Endogenous biosynthesis of n-3 long-chain PUFA in Atlantic salmon |
author_facet |
Mock, Thomas S. Francis, David S. Jago, Matthew K. Glencross, Brett D. Smullen, Richard P. Turchini, Giovanni M. |
author_sort |
Mock, Thomas S. |
title |
Endogenous biosynthesis of n-3 long-chain PUFA in Atlantic salmon |
title_short |
Endogenous biosynthesis of n-3 long-chain PUFA in Atlantic salmon |
title_full |
Endogenous biosynthesis of n-3 long-chain PUFA in Atlantic salmon |
title_fullStr |
Endogenous biosynthesis of n-3 long-chain PUFA in Atlantic salmon |
title_full_unstemmed |
Endogenous biosynthesis of n-3 long-chain PUFA in Atlantic salmon |
title_sort |
endogenous biosynthesis of n-3 long-chain pufa in atlantic salmon |
publisher |
Cambridge University Press (CUP) |
publishDate |
2019 |
url |
http://dx.doi.org/10.1017/s0007114519000473 https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0007114519000473 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
British Journal of Nutrition volume 121, issue 10, page 1108-1123 ISSN 0007-1145 1475-2662 |
op_rights |
https://www.cambridge.org/core/terms |
op_doi |
https://doi.org/10.1017/s0007114519000473 |
container_title |
British Journal of Nutrition |
container_volume |
121 |
container_issue |
10 |
container_start_page |
1108 |
op_container_end_page |
1123 |
_version_ |
1811636579074048000 |