Towards a Mechanism for Poly(I·C) Antiviral Priming in Oysters

Viral diseases cause significant losses in aquaculture. Prophylactic measures, such as immune priming, are promising control strategies. Treatment of the Pacific oyster ( Crassostrea gigas ) with the double-stranded RNA analog poly(I·C) confers long-term protection against infection with ostreid her...

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Bibliographic Details
Published in:mBio
Main Author: Martins, Nelson E.
Other Authors: Agence Nationale de la Recherche
Format: Article in Journal/Newspaper
Language:English
Published: American Society for Microbiology 2020
Subjects:
Crassostrea gigas
Pacific oyster
Online Access:http://dx.doi.org/10.1128/mbio.00407-20
https://journals.asm.org/doi/pdf/10.1128/mBio.00407-20
Description
Summary:Viral diseases cause significant losses in aquaculture. Prophylactic measures, such as immune priming, are promising control strategies. Treatment of the Pacific oyster ( Crassostrea gigas ) with the double-stranded RNA analog poly(I·C) confers long-term protection against infection with ostreid herpesvirus 1, the causative agent of Pacific oyster mortality syndrome. In a recent article in mBio , Lafont and coauthors (M. Lafont, A. Vergnes, J. Vidal-Dupiol, J.

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