Prevalence of Mycoplasma genitalium and Antibiotic Resistance-Associated Mutations in Patients at a Sexually Transmitted Infection Clinic in Iceland, and Comparison of the S-DiaMGTV and Aptima Mycoplasma genitalium Assays for Diagnosis

Mycoplasma genitalium is prevalent among attendees in sexually transmitted infection (STI) clinics, and therapy is hampered by rapidly rising levels of resistance to azithromycin and moxifloxacin. In this study, we evaluated, for the first time in Iceland, the prevalence of M. genitalium and azithro...

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Bibliographic Details
Published in:Journal of Clinical Microbiology
Main Authors: Hilmarsdóttir, Ingibjörg, Arnardóttir, Eva Mjöll, Jóhannesdóttir, Elísabet Reykdal, Valsdóttir, Freyja, Golparian, Daniel, Hadad, Ronza, Vigfússon, Hannes Bjarki, Unemo, Magnus
Other Authors: Munson, Erik, Orebro County Council Reseach Committee, Orebro University Hospital, The Scandinavian Society for Antimicrobial Chemotherapy Foundation, Landspítali Háskólasjúkrahús
Format: Article in Journal/Newspaper
Language:English
Published: American Society for Microbiology 2020
Subjects:
Microbiology (medical)
Iceland
Online Access:http://dx.doi.org/10.1128/jcm.01084-20
https://journals.asm.org/doi/pdf/10.1128/JCM.01084-20
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Summary:Mycoplasma genitalium is prevalent among attendees in sexually transmitted infection (STI) clinics, and therapy is hampered by rapidly rising levels of resistance to azithromycin and moxifloxacin. In this study, we evaluated, for the first time in Iceland, the prevalence of M. genitalium and azithromycin and moxifloxacin resistance-associated mutations and assessed the diagnostic performance of the CE/ in vitro diagnosis (IVD)-marked S-DiaMGTV (Diagenode Diagnostics) versus the U.

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