Effect of Vaccination on Pneumococci Isolated from the Nasopharynx of Healthy Children and the Middle Ear of Children with Otitis Media in Iceland

Vaccination with pneumococcal conjugate vaccines (PCVs) disrupts the pneumococcal population. Our aim was to determine the impact of the 10-valent PCV on the serotypes, genetic lineages, and antimicrobial susceptibility of pneumococci isolated from children in Iceland.

Bibliographic Details
Published in:Journal of Clinical Microbiology
Main Authors: Quirk, Sigríður J., Haraldsson, Gunnsteinn, Erlendsdóttir, Helga, Hjálmarsdóttir, Martha Á., van Tonder, Andries J., Hrafnkelsson, Birgir, Sigurdsson, Samuel, Bentley, Stephen D., Haraldsson, Ásgeir, Brueggemann, Angela B., Kristinsson, Karl G.
Other Authors: Diekema, Daniel J., Glaxo Smith Kline Biologicals, Landspitali University Hospital Research Fund, The Eimskip University Fund, The Wellcome Trust Research Fellowship, Oxford University | John Fell Fund, University of Oxford, The Wellcome Trust
Format: Article in Journal/Newspaper
Language:English
Published: American Society for Microbiology 2018
Subjects:
Online Access:http://dx.doi.org/10.1128/jcm.01046-18
https://journals.asm.org/doi/pdf/10.1128/JCM.01046-18
Description
Summary:Vaccination with pneumococcal conjugate vaccines (PCVs) disrupts the pneumococcal population. Our aim was to determine the impact of the 10-valent PCV on the serotypes, genetic lineages, and antimicrobial susceptibility of pneumococci isolated from children in Iceland.