Depressed in vitro and in vivo antibody response and adoptive transfer of delayed hypersensitivity to myoglobin with spleen cells of mice chronically infected with Schistosoma japonicum and injected with myoglobin

Spleen cells from C57BL/6J mice infected for 21 weeks with Schistosoma japonicum did not show an in vitro secondary antibody response upon challenge with sperm whale myoglobin. Mice infected for 13 weeks showed almost no in vivo secondary antibody response to this antigen. Spleen cells from mice inf...

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Bibliographic Details
Published in:Infection and Immunity
Main Authors: Garb, K S, Stavitsky, A B
Format: Article in Journal/Newspaper
Language:English
Published: American Society for Microbiology 1984
Subjects:
Infectious Diseases
Immunology
Microbiology
Parasitology
Sperm whale
Online Access:http://dx.doi.org/10.1128/iai.43.3.1097-1099.1984
https://journals.asm.org/doi/pdf/10.1128/iai.43.3.1097-1099.1984
Description
Summary:Spleen cells from C57BL/6J mice infected for 21 weeks with Schistosoma japonicum did not show an in vitro secondary antibody response upon challenge with sperm whale myoglobin. Mice infected for 13 weeks showed almost no in vivo secondary antibody response to this antigen. Spleen cells from mice infected for 12 to 21 weeks did not adoptively transfer delayed hypersensitivity to this antigen.

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