Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy

ABSTRACT In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficie...

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Published in:Clinical and Vaccine Immunology
Main Authors: Friborg, Jeppe T., Jarrett, Ruth F., Koch, Anders, Garred, Peter, Freeland, June M. L., Andersen, Andreas, Melbye, Mads
Format: Article in Journal/Newspaper
Language:English
Published: American Society for Microbiology 2010
Subjects:
Greenland
Online Access:http://dx.doi.org/10.1128/cvi.00527-09
https://journals.asm.org/doi/pdf/10.1128/CVI.00527-09
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spelling crasmicro:10.1128/cvi.00527-09 2024-05-19T07:41:12+00:00 Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy Friborg, Jeppe T. Jarrett, Ruth F. Koch, Anders Garred, Peter Freeland, June M. L. Andersen, Andreas Melbye, Mads 2010 http://dx.doi.org/10.1128/cvi.00527-09 https://journals.asm.org/doi/pdf/10.1128/CVI.00527-09 en eng American Society for Microbiology https://journals.asm.org/non-commercial-tdm-license Clinical and Vaccine Immunology volume 17, issue 9, page 1484-1487 ISSN 1556-6811 1556-679X journal-article 2010 crasmicro https://doi.org/10.1128/cvi.00527-09 2024-05-02T06:49:22Z ABSTRACT In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy. Article in Journal/Newspaper Greenland ASM Journals (American Society for Microbiology) Clinical and Vaccine Immunology 17 9 1484 1487
institution Open Polar
collection ASM Journals (American Society for Microbiology)
op_collection_id crasmicro
language English
description ABSTRACT In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.
format Article in Journal/Newspaper
author Friborg, Jeppe T.
Jarrett, Ruth F.
Koch, Anders
Garred, Peter
Freeland, June M. L.
Andersen, Andreas
Melbye, Mads
spellingShingle Friborg, Jeppe T.
Jarrett, Ruth F.
Koch, Anders
Garred, Peter
Freeland, June M. L.
Andersen, Andreas
Melbye, Mads
Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy
author_facet Friborg, Jeppe T.
Jarrett, Ruth F.
Koch, Anders
Garred, Peter
Freeland, June M. L.
Andersen, Andreas
Melbye, Mads
author_sort Friborg, Jeppe T.
title Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy
title_short Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy
title_full Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy
title_fullStr Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy
title_full_unstemmed Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy
title_sort mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy
publisher American Society for Microbiology
publishDate 2010
url http://dx.doi.org/10.1128/cvi.00527-09
https://journals.asm.org/doi/pdf/10.1128/CVI.00527-09
genre Greenland
genre_facet Greenland
op_source Clinical and Vaccine Immunology
volume 17, issue 9, page 1484-1487
ISSN 1556-6811 1556-679X
op_rights https://journals.asm.org/non-commercial-tdm-license
op_doi https://doi.org/10.1128/cvi.00527-09
container_title Clinical and Vaccine Immunology
container_volume 17
container_issue 9
container_start_page 1484
op_container_end_page 1487
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