Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy

ABSTRACT In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficie...

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Bibliographic Details
Published in:Clinical and Vaccine Immunology
Main Authors: Friborg, Jeppe T., Jarrett, Ruth F., Koch, Anders, Garred, Peter, Freeland, June M. L., Andersen, Andreas, Melbye, Mads
Format: Article in Journal/Newspaper
Language:English
Published: American Society for Microbiology 2010
Subjects:
Greenland
Online Access:http://dx.doi.org/10.1128/cvi.00527-09
https://journals.asm.org/doi/pdf/10.1128/CVI.00527-09
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Summary:ABSTRACT In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.

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