gyrA and parC Mutations and Associated Quinolone Resistance in Vibrio anguillarum Serotype O2b Strains Isolated from Farmed Atlantic Cod ( Gadus morhua ) in Norway

ABSTRACT MIC testing of Vibrio anguillarum isolates recovered from diseased farmed Atlantic cod revealed oxolinic acid MICs of ≤0.001, 0.06, and 16 μg ml −1 . Single gyrA Ser-Ile substitutions were identified at position 83 of the intermediate and resistant strains, while a parC Ser-Leu substitution...

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Bibliographic Details
Published in:Antimicrobial Agents and Chemotherapy
Main Authors: Colquhoun, D. J., Aarflot, L., Melvold, C. F.
Format: Article in Journal/Newspaper
Language:English
Published: American Society for Microbiology 2007
Subjects:
Norway
atlantic cod
Gadus morhua
Online Access:http://dx.doi.org/10.1128/aac.00315-07
https://journals.asm.org/doi/pdf/10.1128/AAC.00315-07
Description
Summary:ABSTRACT MIC testing of Vibrio anguillarum isolates recovered from diseased farmed Atlantic cod revealed oxolinic acid MICs of ≤0.001, 0.06, and 16 μg ml −1 . Single gyrA Ser-Ile substitutions were identified at position 83 of the intermediate and resistant strains, while a parC Ser-Leu substitution at position 85 was found only in the resistant strain.

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