Molecular Characterization of Ofloxacin-Resistant Mycobacterium tuberculosis Strains from Russia
ABSTRACT In this work, we studied the variation in the gyrA and gyrB genes in ofloxacin- and multidrug-resistant Mycobacterium tuberculosis strains circulating in northwest Russia. Comparison with spoligotyping data suggested that similar to the spread of multidrug-resistant tuberculosis, the spread...
Published in: | Antimicrobial Agents and Chemotherapy |
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Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
American Society for Microbiology
2008
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Subjects: | |
Online Access: | http://dx.doi.org/10.1128/aac.00036-08 https://journals.asm.org/doi/pdf/10.1128/AAC.00036-08 |
Summary: | ABSTRACT In this work, we studied the variation in the gyrA and gyrB genes in ofloxacin- and multidrug-resistant Mycobacterium tuberculosis strains circulating in northwest Russia. Comparison with spoligotyping data suggested that similar to the spread of multidrug-resistant tuberculosis, the spread of fluoroquinolone-resistant tuberculosis in Russia may be due, at least partly, to the prevalence of the Beijing genotype in a local population of M. tuberculosis . |
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