Crustacean Color-Change Hormone: Amino Acid Sequence and Chemical Synthesis

The blanching hormone of the prawn, Pandalus borealis , is pGlu-Leu-Asn-Phe-Ser-Pro-Gly-Trp-NH 2 . Its structure was settled by a combination of mass spectrometry and Edman-dansyl analysis of a thermolysin fragment. Confirmation of the structure was obtained by chemical synthesis from amino acids. T...

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Bibliographic Details
Published in:Science
Main Authors: Fernlund, Per, Josefsson, Lars
Format: Article in Journal/Newspaper
Language:English
Published: American Association for the Advancement of Science (AAAS) 1972
Subjects:
Online Access:http://dx.doi.org/10.1126/science.177.4044.173
https://www.science.org/doi/pdf/10.1126/science.177.4044.173
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Summary:The blanching hormone of the prawn, Pandalus borealis , is pGlu-Leu-Asn-Phe-Ser-Pro-Gly-Trp-NH 2 . Its structure was settled by a combination of mass spectrometry and Edman-dansyl analysis of a thermolysin fragment. Confirmation of the structure was obtained by chemical synthesis from amino acids. This neurosecreted hormone is active in picogram amounts when tested in shrimps.