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Aedes aegypti CCEae3A carboxylase expression confers carbamate, organophosphate and limited pyrethroid resistance in a model transgenic mosquito.

by Beth C Poulton, Fraser Colman, Amalia Anthousi, David B Sattelle, Gareth J Lycett
Published in PLOS Neglected Tropical Diseases (2024)

Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance...

by Steven D Buckingham, Frederick A Partridge, Beth C Poulton, Benjamin S Miller, Rachel A McKendry, Gareth J Lycett, David B Sattelle
Published in PLOS Neglected Tropical Diseases (2021)

Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo.

by Frederick A Partridge, Emma A Murphy, Nicky J Willis, Carole J R Bataille, Ruth Forman, Narinder Heyer-Chauhan, Bruno Marinič, Daniel J C Sowood, Graham M Wynne, Kathryn J Else, Angela J Russell, David B Sattelle
Published in PLOS Neglected Tropical Diseases (2017)

A drug repurposing screen for whipworms informed by comparative genomics.

by Avril Coghlan, Frederick A Partridge, María Adelaida Duque-Correa, Gabriel Rinaldi, Simon Clare, Lisa Seymour, Cordelia Brandt, Tapoka T Mkandawire, Catherine McCarthy, Nancy Holroyd, Marina Nick, Anwen E Brown, Sirapat Tonitiwong, David B Sattelle, Matthew Berriman
Published in PLOS Neglected Tropical Diseases (2023)

2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm.

by Frederick A Partridge, Ruth Forman, Nicky J Willis, Carole J R Bataille, Emma A Murphy, Anwen E Brown, Narinder Heyer-Chauhan, Bruno Marinič, Daniel J C Sowood, Graham M Wynne, Kathryn J Else, Angela J Russell, David B Sattelle
Published in PLOS Neglected Tropical Diseases (2018)