Search Results

A study of b-secretase cleaved Alzheimer amyloid precursor protein

by Sennvik, Kristina
Published 2002

Exploring the potential pathogenic mechanism of Alzheimer’s disease through in silico analysis of gamma secretase

by Visentin, David
Published 2021

Exploring the potential pathogenic mechanism of Alzheimer’s disease through in silico analysis of gamma secretase

by Visentin, David
Published 2021

An isogenic panel of App knock-in mouse models: Profiling β-secretase inhibition and endosomal abnormalities

by Watamura, Naoto, Sato, Kaori, Shiihashi, Gen, Iwasaki, Ayami, Kamano, Naoko, Takahashi, Mika, Sekiguchi, Misaki, Mihira, Naomi, Fujioka, Ryo, Nagata, Kenichi, Hashimoto, Shoko, Saito, Takashi, Ohshima, Toshio, Saido, Takaomi C., Sasaguri, Hiroki
Published in Science Advances (2022)

Charakterisierung eines Dimerisierungsmotivs in der Aβ-Region des Amyloid- Vorläuferproteins : Mechanismus der Aβ-Entstehung : Characterization of a dimerization motif within the A...

by Münter, Lisa-Marie
Published 2008

The Arctic Alzheimer mutation favors intracellular amyloid‐β production by making amyloid precursor protein less available to α‐secretase

by Sahlin, Charlotte, Lord, Anna, Magnusson, Kristina, Englund, Hillevi, Almeida, Claudia G., Greengard, Paul, Nyberg, Fred, Gouras, Gunnar K., Lannfelt, Lars, Nilsson, Lars N.G.
Published in Journal of Neurochemistry (2007)

Neuroactive venom compounds obtained from Phlogiellus bundokalbo as potential leads for neurodegenerative diseases: insights on their acetylcholinesterase and beta-secretase inhibitory activities in vitro

by Simon Miguel M. Lopez, Jeremey S. Aguilar, Jerene Bashia B. Fernandez, Angelic Gayle J. Lao, Mitzi Rain R. Estrella, Mark Kevin P. Devanadera, Cydee Marie V. Ramones, Aaron Joseph L. Villaraza, Leonardo A. Guevarra Jr., Myla R. Santiago-Bautista, Librado A. Santiago
Published in Journal of Venomous Animals and Toxins including Tropical Diseases (2021)

P4–041: The Arctic Alzheimer mutation favors Aβ production by making APP less available to α–secretase at the cell surface

by Stenh, Charlotte, Lord, Anna, Magnusson, Kristina, Englund, Hillevi, Almeida, Claudia G., Greengard, Paul, Nyberg, Fred, Gouras, Gunnar K., Lannfelt, Lars, Nilsson, Lars N.G.
Published in Alzheimer's & Dementia (2006)

Characterization of the novel “Uppsala mutation” causing a familial form of early onset Alzheimer’s disease

by Pagnon de la Vega, María
Published 2021

Pathogenic Mechanisms of the Arctic Alzheimer Mutation

by Sahlin, Charlotte
Published 2007

The C99 domain of the amyloid precursor protein resides in the disordered membrane phase

by Capone, Ricardo, Tiwari, Ajit, Hadziselimovic, Arina, Peskova, Yelena, Hutchison, James M., Sanders, Charles R., Kenworthy, Anne K.
Published in Journal of Biological Chemistry (2021)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

by Schilling, Sandra, Pradhan, Ajay, Heesch, Amelie, Helbig, Andrea, Blennow, Kaj, Koch, Christian, Bertgen, Lea, Koo, Edward H., Brinkmalm, Gunnar, Zetterberg, Henrik, Eggert, Simone
Published in Acta Neuropathologica Communications (2023)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

by Schilling, S, Pradhan, A, Heesch, A, Helbig, A, Blennow, K, Koch, C, Bertgen, L, Koo, EH, Brinkmalm, G, Zetterberg, H, Kins, S, Eggert, S
Published 2023

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

by Sandra Schilling, Ajay Pradhan, Amelie Heesch, Andrea Helbig, Kaj Blennow, Christian Koch, Lea Bertgen, Edward H. Koo, Gunnar Brinkmalm, Henrik Zetterberg, Stefan Kins, Simone Eggert
Published in Acta Neuropathologica Communications (2023)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

by Schilling, S., Pradhan, A., Heesch, A., Helbig, A., Blennow, K., Koch, C., Bertgen, L., Koo, E., Brinkmalm, G., Zetterberg, H., Kins, S., Eggert, S.
Published in Acta Neuropathologica Communications (2023)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

by Schilling, Sandra, Pradhan, Ajay, Heesch, Amelie, Helbig, Andrea, Blennow, Kaj, Koch, Christian, Bertgen, Lea, Koo, Edward H., Brinkmalm, Gunnar, Zetterberg, Henrik, Kins, Stefan, Eggert, Simone
Published in Acta Neuropathologica Communications (2023)

Distribution and pathophysiological role of amyloid precursor protein and presenilin 1 : characterization in rats and in vitro studies on the pathogenic arctic mutation

by Nilsberth, Camilla
Published 2002

Regulation of osteoprotegerin expression by Notch signaling in human oral squamous cell carcinoma cell line

by Jeeranan Manokawinchoke, Thanaphum Osathanon, Prasit Pavasant
Published in Asian Pacific Journal of Tropical Biomedicine (2016)

The Arctic Alzheimer mutation enhances sensitivity to toxic stress in human neuroblastoma cells

by Sennvik, Kristina, Nilsberth, Camilla, Stenh, Charlotte, Lannfelt, Lars, Benedikz, Eirikur
Published 2002

Point Mutations in Ab Result in the Formation of Distinct Polymorphic Aggregates in the Presence of Lipid Bilayers

by Phillip M. Pifer, Elizabeth A. Yates, Justin Legleiter