Search Results

Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains

by Yang, Yang, Zhang, Wenjuan, Murzin, Alexey G., Schweighauser, Manuel, Huang, Melissa, Lövestam, Sofia, Peak-Chew, Sew Y., Saito, Takashi, Saido, Takaomi C., Macdonald, Jennifer, Lavenir, Isabelle, Ghetti, Bernardino, Graff, Caroline, Kumar, Amit, Nordberg, Agneta, Goedert, Michel, Scheres, Sjors H. W.
Published in Acta Neuropathologica (2023)

The Arctic AβPP mutation leads to Alzheimer’s disease pathology with highly variable topographic deposition of differentially truncated Aβ

by Kalimo, Hannu, Lalowski, Maciej, Bogdanovic, Nenad, Philipson, Ola, Bird, Thomas D, Nochlin, David, Schellenberg, Gerard D, Brundin, RoseMarie, Olofsson, Tommie, Soliymani, Rabah, Baumann, Marc, Wirths, Oliver, Bayer, Thomas A, Nilsson, Lars N, Basun, Hans, Lannfelt, Lars, Ingelsson, Martin
Published in Acta Neuropathologica Communications (2013)

Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis

by Sakakibara, Yasufumi, Sekiya, Michiko, Saito, Takashi, Takaomi Saido, Iijima, Koichi
Published 2018

Fecal Implants From AppNL–G–F and AppNL–G–F/E4 Donor Mice Sufficient to Induce Behavioral Phenotypes in Germ-Free Mice

by Payel Kundu, Keaton Stagaman, Kristin Kasschau, Sarah Holden, Natalia Shulzhenko, Thomas J. Sharpton, Jacob Raber
Published in Frontiers in Behavioral Neuroscience (2022)

Image_1_Fecal Implants From AppNL–G–F and AppNL–G–F/E4 Donor Mice Sufficient to Induce Behavioral Phenotypes in Germ-Free Mice.JPEG

by Payel Kundu, Keaton Stagaman, Kristin Kasschau, Sarah Holden, Natalia Shulzhenko, Thomas J. Sharpton, Jacob Raber
Published 2022

Image_2_Fecal Implants From AppNL–G–F and AppNL–G–F/E4 Donor Mice Sufficient to Induce Behavioral Phenotypes in Germ-Free Mice.JPEG

by Payel Kundu, Keaton Stagaman, Kristin Kasschau, Sarah Holden, Natalia Shulzhenko, Thomas J. Sharpton, Jacob Raber
Published 2022

Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vi...

by Tackenberg, Christian, Kulic, Luka, Nitsch, Roger M
Published 2020

The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ.

by Kalimo, Hannu, Lalowski, Maciej, Bogdanovic, Nenad, Philipson, Ola, Bird, Thomas D., Nochlin, David, Schellenberg, Gerard D., Brundin, Rosemarie, Olofsson, Tommie, Soliymani, Rabah, Baumann, Marc, Wirths, Oliver, Bayer, Thomas A., Nilsson, Lars, Basun, Hans, Lannfelt, Lars, Ingelsson, Martin
Published in Acta Neuropathologica Communications (2013)

Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aβ) in murine mod...

by Rammes, Gerhard, Mattusch, Corinna, Wulff, Matthias, Seeser, Franziska, Kreuzer, Matthias, Zhu, Kaichuan, Deussing, Jan M, Herms, Jochen, Parsons, Chris G
Published in Neuropharmacology (2017)

beta-Amyloid Monomers Are Neuroprotective

by M. L. Giuffrida, F. Caraci, B. Pignataro, S. Cataldo, P. De Bona, Gemma Molinaro, G. Pappalardo, A. Messina, A. Palmigiano, D. Garozzo, E. Rizzarelli, A. Copani, BRUNO, Valeria Maria Gloria, NICOLETTI, Ferdinando
Published in Journal of Neuroscience (2009)

Rarity of the Alzheimer disease-protective APP A673T variant in the United States.

by Wang, LS, Naj, AC, Graham, RR, Crane, PK, Kunkle, BW, Cruchaga, C, Murcia, JD, Cannon-Albright, L, Baldwin, CT, Zetterberg, H, Blennow, K, Kukull, WA, Faber, KM, Schupf, N, Norton, MC, Tschanz, JT, Munger, RG, Corcoran, CD, Rogaeva, E, Alzheimer's Disease Genetics Consortium, Lin, CF, Dombroski, BA, Cantwell, LB, Partch, A, Valladares, O, Hakonarson, H, St George-Hyslop, P, Green, RC, Goate, AM, Foroud, TM, Carney, RM, Larson, EB, Behrens, TW, Kauwe, JS, Haines, JL, Farrer, LA, Pericak-Vance, MA, Mayeux, R, Schellenberg, GD, National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-, Albert, MS, Albin, RL, Apostolova, LG, Arnold, SE, Barber, R, Barmada, M, Barnes, LL, Beach, TG, Becker, JT, Beecham, GW, Beekly, D, Bennett, DA, Bigio, EH, Bird, TD, Blacker, D, Boeve, BF, Bowen, JD, Boxer, A, Burke, JR, Buxbaum, JD, Cairns, NJ, Cao, C, Carlson, CS, Carroll, SL, Chui, HC, Clark, DG, Cribbs, DH, Crocco, EA, DeCarli, C, DeKosky, ST, Demirci, FY, Dick, M, Dickson, DW, Duara, R, Ertekin-Taner, N, Fallon, KB, Farlow, MR, Ferris, S, Frosch, MP, Galasko, DR, Ganguli, M, Gearing, M, Geschwind, DH, Ghetti, B, Gilbert, JR, Glass, JD, Graff-Radford, NR, Growdon, JH, Hamilton, RL, Hamilton-Nelson, KL, Harrell, LE, Head, E, Honig, LS, Hulette, CM, Hyman, BT, Jarvik, GP, Jicha, GA, Jin, LW, Jun, G, Kamboh, MI, Karydas, A, Kaye, JA, Kim, R, Koo, EH, Kowall, NW, Kramer, JH, LaFerla, FM, Lah, JJ, Leverenz, JB, Levey, AI, Li, G, Lieberman, AP, Lopez, OL, Lunetta, KL, Lyketsos, CG, Mack, WJ, Marson, DC, Martin, ER, Martiniuk, F, Mash, DC, Masliah, E, McCormick, WC, McCurry, SM, McDavid, AN, McKee, AC, Mesulam, WM, Miller, BL, Miller, CA, Miller, JW, Montine, TJ, Morris, JC, Murrell, JR, Olichney, JM, Parisi, JE, Perry, W, Peskind, E, Petersen, RC, Pierce, A, Poon, WW, Potter, H, Quinn, JF, Raj, A, Raskind, M, Reiman, EM, Reisberg, B, Reitz, C, Ringman, JM, Roberson, ED, Rosen, HJ, Rosenberg, RN, Sano, M, Saykin, AJ, Schneider, JA, Schneider, LS, Seeley, WW, Smith, AG, Sonnen, JA, Spina, S, Stern, RA, Tanzi, RE, Thornton-Wells, TA, Trojanowski, JQ, Troncoso, JC, Tsuang, DW, Van Deerlin, VM, Van Eldik, LJ, Vardarajan, BN, Vinters, HV, Vonsattel, JP, Weintraub, S, Welsh-Bohmer, KA, Williamson, J, Wishnek, S, Woltjer, RL, Wright, CB, Younkin, SG, Yu, CE, Yu, L
Published 2015

Die Bedeutung der NMDA-Rezeptoruntereinheit NR2B in der Vermittlung synaptotoxischer Effekte verschiedener Amyloid β-Arten

by Seeser, Franziska Katharina
Published 2018

Die Bedeutung der NMDA-Rezeptoruntereinheit NR2B in der Vermittlung synaptotoxischer Effekte verschiedener Amyloid β-Arten

by Seeser, Franziska Katharina
Published 2018

Neuroactive venom compounds obtained from Phlogiellus bundokalbo as potential leads for neurodegenerative diseases: insights on their acetylcholinesterase and beta-secretase inhibi...

by Simon Miguel M. Lopez, Jeremey S. Aguilar, Jerene Bashia B. Fernandez, Angelic Gayle J. Lao, Mitzi Rain R. Estrella, Mark Kevin P. Devanadera, Cydee Marie V. Ramones, Aaron Joseph L. Villaraza, Leonardo A. Guevarra Jr., Myla R. Santiago-Bautista, Librado A. Santiago
Published in Journal of Venomous Animals and Toxins including Tropical Diseases (2021)