Search Results

Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains

by Yang, Yang, Zhang, Wenjuan, Murzin, Alexey G, Schweighauser, Manuel, Huang, Melissa, Lovestam, Sofia, Peak-Chew, Sew Y, Saito, Takashi, Saido, Takaomi C, Macdonald, Jennifer, Lavenir, Isabelle, Ghetti, Bernardino, Graff, Caroline, Kumar, Amit, Nordberg, Agneta, Goedert, Michel, Scheres, Sjors HW
Published 2023

The Arctic AβPP mutation leads to Alzheimer’s disease pathology with highly variable topographic deposition of differentially truncated Aβ

by Kalimo, Hannu, Lalowski, Maciej, Bogdanovic, Nenad, Philipson, Ola, Bird, Thomas D, Nochlin, David, Schellenberg, Gerard D, Brundin, RoseMarie, Olofsson, Tommie, Soliymani, Rabah, Baumann, Marc, Wirths, Oliver, Bayer, Thomas A, Nilsson, Lars NG, Basun, Hans, Lannfelt, Lars, Ingelsson, Martin
Published 2013

The Arctic AβPP mutation leads to Alzheimer’s disease pathology with highly variable topographic deposition of differentially truncated Aβ

by Kalimo, Hannu, Lalowski, Maciej, Bogdanovic, Nenad, Philipson, Ola, Bird, Thomas D, Nochlin, David, Schellenberg, Gerard D, Brundin, RoseMarie, Olofsson, Tommie, Soliymani, Rabah, Baumann, Marc, Wirths, Oliver, Bayer, Thomas A, Nilsson, Lars NG, Basun, Hans, Lannfelt, Lars, Ingelsson, Martin
Published in Acta Neuropathologica Communications (2013)

Recent Advances in the Modeling of Alzheimer’s Disease

by Hiroki Sasaguri, Shoko Hashimoto, Naoto Watamura, Kaori Sato, Risa Takamura, Kenichi Nagata, Satoshi Tsubuki, Toshio Ohshima, Atsushi Yoshiki, Kenya Sato, Wakako Kumita, Erika Sasaki, Shinobu Kitazume, Per Nilsson, Bengt Winblad, Takashi Saito, Nobuhisa Iwata, Takaomi C. Saido
Published in Frontiers in Neuroscience (2022)

Recent Advances in the Modeling of Alzheimer’s Disease

by Sasaguri, Hiroki, Hashimoto, Shoko, Watamura, Naoto, Sato, Kaori, Takamura, Risa, Nagata, Kenichi, Tsubuki, Satoshi, Ohshima, Toshio, Yoshiki, Atsushi, Sato, Kenya, Kumita, Wakako, Sasaki, Erika, Kitazume, Shinobu, Nilsson, Per, Winblad, Bengt, Saito, Takashi, Iwata, Nobuhisa, Saido, Takaomi C.
Published in Frontiers in Neuroscience (2022)

Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vi...

by Tackenberg, Christian, Kulic, Luka, Nitsch, Roger M.
Published in PLOS ONE (2020)

Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer’s disease

by Sakakibara, Yasufumi, Sekiya, Michiko, Saito, Takashi, Takaomi Saido, Iijima, Koichi
Published 2019

Integrated analysis of behavioral, epigenetic, and gut microbiome analyses in App NL-G-F , App NL-F , and wild type mice

by Payel Kundu, Eileen Ruth S. Torres, Keaton Stagaman, Kristin Kasschau, Mariam Okhovat, Sarah Holden, Samantha Ward, Kimberly A. Nevonen, Brett A. Davis, Takashi Saito, Takaomi C. Saido, Lucia Carbone, Thomas J. Sharpton, Jacob Raber
Published in Scientific Reports (2021)

Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains.

by Yang, Yang, Zhang, Wenjuan, Murzin, Alexey G, Schweighauser, Manuel, Huang, Melissa, Lövestam, Sofia, Peak-Chew, Sew Y, Saito, Takashi, Saido, Takaomi C, Macdonald, Jennifer, Lavenir, Isabelle, Ghetti, Bernardino, Graff, Caroline, Kumar, Amit, Nordberg, Agneta, Goedert, Michel, Scheres, Sjors HW
Published 2023

Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vi...

by Tackenberg, Christian, Kulic, Luka, Nitsch, Roger M.
Published 2020

The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ.

by Kalimo, Hannu, Lalowski, Maciej, Bogdanovic, Nenad, Philipson, Ola, Bird, Thomas D., Nochlin, David, Schellenberg, Gerard D., Brundin, Rosemarie, Olofsson, Tommie, Soliymani, Rabah, Baumann, Marc, Wirths, Oliver, Bayer, Thomas A., Nilsson, Lars, Basun, Hans, Lannfelt, Lars, Ingelsson, Martin
Published in Acta Neuropathologica Communications (2013)

Involvement of GluN2B subunit containing N-methyl-D-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aβ) in murine mod...

by Rammes, G., Mattusch, C., Wulff, M., Seeser, F., Kreuzer, M., Zhu, K., Deussing, J., Herms, J., Parsons, C.
Published in Neuropharmacology (2017)

Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains

by Yang, Yang, Zhang, Wenjuan, Murzin, Alexey G., Schweighauser, Manuel, Huang, Melissa, Lövestam, Sofia, Peak‑Chew, Sew Y., Saito, Takashi, Saido, Takaomi C., Macdonald, Jennifer, Lavenir, Isabelle, Ghetti, Bernardino, Graff, Caroline, Kumar, Amit, Nordberg, Agneta, Goedert, Michel, Scheres, Sjors H. W.
Published in Acta Neuropathologica (2023)

Fecal Implants From AppNL–G–F and AppNL–G–F/E4 Donor Mice Sufficient to Induce Behavioral Phenotypes in Germ-Free Mice

by Kundu, Payel, Stagaman, Keaton, Kasschau, Kristin, Holden, Sarah, Shulzhenko, Natalia, Sharpton, Thomas J., Raber, Jacob
Published in Frontiers in Behavioral Neuroscience (2022)

Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

by Merlini, M, Meyer, E P, Ulmann-Schuler, A, Nitsch, R M
Published 2011

Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vi...

by Christian Tackenberg, Luka Kulic, Roger M Nitsch
Published in PLOS ONE (2020)

Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer’s disease

by Sakakibara, Yasufumi, Sekiya, Michiko, Saito, Takashi, Takaomi Saido, Iijima, Koichi
Published 2019

Fecal Implants From App(NL–G–F) and App(NL–G–F/E4) Donor Mice Sufficient to Induce Behavioral Phenotypes in Germ-Free Mice

by Kundu, Payel, Stagaman, Keaton, Kasschau, Kristin, Holden, Sarah, Shulzhenko, Natalia, Sharpton, Thomas J., Raber, Jacob
Published in Frontiers in Behavioral Neuroscience (2022)

Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis

by Sakakibara, Yasufumi, Sekiya, Michiko, Saito, Takashi, Takaomi Saido, Iijima, Koichi
Published 2018

Integrated analysis of behavioral, epigenetic, and gut microbiome analyses in App(NL-G-F), App(NL-F), and wild type mice

by Kundu, Payel, Torres, Eileen Ruth S., Stagaman, Keaton, Kasschau, Kristin, Okhovat, Mariam, Holden, Sarah, Ward, Samantha, Nevonen, Kimberly A., Davis, Brett A., Saito, Takashi, Saido, Takaomi C., Carbone, Lucia, Sharpton, Thomas J., Raber, Jacob
Published in Scientific Reports (2021)