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1by Jair L Siqueira-Neto, Anjan Debnath, Laura-Isobel McCall, Jean A Bernatchez, Momar Ndao, Sharon L Reed, Philip J Rosenthal“...Cysteine proteases (CPs) play key roles in the pathogenesis of protozoan parasites, including cell...”
Published in PLOS Neglected Tropical Diseases (2018)
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2by Carolina De Marco Verissimo, Heather L Jewhurst, Irina G Tikhonova, Rolf T Urbanus, Aaron G Maule, John P Dalton, Krystyna Cwiklinski“...Serine protease inhibitors (serpins) regulate proteolytic events within diverse biological...”
Published in PLOS Neglected Tropical Diseases (2020)
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3by Conor R Caffrey, Louise Goupil, Karina M Rebello, John P Dalton, David Smith“...We briefly review cysteine proteases (orthologs of mammalian cathepsins B, L, F, and C...”
Published in PLOS Neglected Tropical Diseases (2018)
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5by Jon J Vermeire, Lorine D Lantz, Conor R Caffrey“... of the peptidyl cysteine protease inhibitors (CPIs) K11002 (4-mopholino-carbonyl-phenylalanyl-homophenylalanyl...”
Published in PLoS Neglected Tropical Diseases (2012)
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7by Sumaira Z Hasnain, Michael A McGuckin, Richard K Grencis, David J Thornton“...174T, were treated with ESPs. We demonstrate that serine protease(s) secreted by the nematode have...”
Published in PLoS Neglected Tropical Diseases (2012)
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8by Porntip Pinlaor, Natthawut Kaewpitoon, Thewarach Laha, Banchob Sripa, Sasithorn Kaewkes, Maria E Morales, Victoria H Mann, Sandi K Parriott, Sutas Suttiprapa, Mark W Robinson, Joyce To, John P Dalton, Alex Loukas, Paul J Brindley“... duct, the parasite secretes several cathepsin F cysteine proteases that may induce or contribute...”
Published in PLoS Neglected Tropical Diseases (2009)
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9by Xiaoying Xie, Zhanshuai Wu, Yuhong Wu, Jing Liu, Xinyuan Chen, Xiaoqian Shi, Caiheng Wei, Jiasheng Li, Jiahui Lv, Qing Li, Lili Tang, Shanshan He, Tingzheng Zhan, Zeli Tang“... in the host. This study aimed to evaluate the therapeutic effects of cysteine protease (CsCP) and adult crude...”
Published in PLOS Neglected Tropical Diseases (2022)
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10by Louise S Goupil, Sam L Ivry, Ivy Hsieh, Brian M Suzuki, Charles S Craik, Anthony J O'Donoghue, James H McKerrow“...Proteases perform numerous vital functions in flatworms, many of which are likely to be conserved...”
Published in PLOS Neglected Tropical Diseases (2016)
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11by Takahisa Furuta, Lyre Anni Murao, Nguyen Thi Phuong Lan, Nguyen Tien Huy, Vu Thi Que Huong, Tran Thi Thuy, Vo Dinh Tham, Cao Thi Phi Nga, Tran Thi Ngoc Ha, Yasukazu Ohmoto, Mihoko Kikuchi, Kouichi Morita, Michio Yasunami, Kenji Hirayama, Naohiro Watanabe“.... By day 4 of admission, VEGF, sVEGFRs, and proteases levels had returned to similar levels as DF...”
Published in PLoS Neglected Tropical Diseases (2012)
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12Trypsin- and Chymotrypsin-like serine proteases in schistosoma mansoni-- 'the undiscovered country'.by Martin Horn, Pavla Fajtová, Liliana Rojo Arreola, Lenka Ulrychová, Pavla Bartošová-Sojková, Zdeněk Franta, Anna V Protasio, David Opavský, Jiří Vondrášek, James H McKerrow, Michael Mareš, Conor R Caffrey, Jan Dvořák“... in the vasculature of permissive mammalian hosts, including humans. Proteolytic enzymes (proteases) are crucial...”
Published in PLoS Neglected Tropical Diseases (2014)
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13by Alexandra Grote, Conor R Caffrey, Karina M Rebello, David Smith, John P Dalton, Sara Lustigman“... revealed the vital contribution of cysteine proteases to invasion of and migration by (larval) helminth...”
Published in PLOS Neglected Tropical Diseases (2018)
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14by Byoung-Kuk Na, Young-An Bae, Young-Gun Zo, Youngchool Choe, Seon-Hee Kim, Prashant V Desai, Mitchell A Avery, Charles S Craik, Tong-Soo Kim, Philip J Rosenthal, Yoon Kong“...Multiple cysteine proteases of malaria parasites are required for maintenance of parasite metabolic...”
Published in PLoS Neglected Tropical Diseases (2010)
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15by Li Na Liu, Zhong Quan Wang, Xi Zhang, Peng Jiang, Xin Qi, Ruo Dan Liu, Zi Fang Zhang, Jing Cui“... helminthiases. The aim of this study was to characterize Spirometra erinaceieuropaei cysteine protease (SeCP...”
Published in PLOS Neglected Tropical Diseases (2015)
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16by Antonio C B Burtoloso, Sérgio de Albuquerque, Mark Furber, Juliana C Gomes, Cristiana Gonçalez, Peter W Kenny, Andrei Leitão, Carlos A Montanari, José Carlos Quilles, Jean F R Ribeiro, Josmar R Rocha“...The cysteine protease cruzipain is considered to be a validated target for therapeutic intervention...”
Published in PLOS Neglected Tropical Diseases (2017)
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17by Shiwanthi L Ranasinghe, Katja Fischer, Wenbao Zhang, Geoffrey N Gobert, Donald P McManus“... host environment, avoiding attack by host enzymes and evading immune responses, but protease inhibitors...”
Published in PLOS Neglected Tropical Diseases (2015)
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18Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway.by Simone L Reynolds, Robert N Pike, Angela Mika, Anna M Blom, Andreas Hofmann, Lakshmi C Wijeyewickrema, Dave Kemp, Katja Fischer“... proteolytically inactive serine protease paralogues (SMIPP-Ss) thought to be implicated in host defence evasion...”
Published in PLoS Neglected Tropical Diseases (2014)
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19by Chihiro Tanigawa, Yoshito Fujii, Masashi Miura, Samson Muuo Nzou, Anne Wanjiru Mwangi, Sachiyo Nagi, Shinjiro Hamano, Sammy M Njenga, Evaristus Chibunna Mbanefo, Kenji Hirayama, Matilu Mwau, Satoshi Kaneko“... in two areas of Kenya, endemic for different species of schistosomiasis. S. mansoni serine protease...”
Published in PLOS Neglected Tropical Diseases (2015)
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20by Ileana Corvo, Anthony J O'Donoghue, Lucía Pastro, Natalia Pi-Denis, Alegra Eroy-Reveles, Leda Roche, James H McKerrow, John P Dalton, Charles S Craik, Conor R Caffrey, José F Tort“...A family of secreted cathepsin L proteases with differential activities is essential for host...”
Published in PLoS Neglected Tropical Diseases (2013)
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