Search Results - Open Polar - "secretase"

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Characterization of the novel “Uppsala mutation” causing a familial form of early onset Alzheimer’s disease

by Pagnon de la Vega, María
Published 2021
“... precursor protein (APP) by β-secretase and γ-secretase, while α-secretase prevents Aβ generation. According...”

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Doctoral or Postdoctoral Thesis
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2

Pathogenic Mechanisms of the Arctic Alzheimer Mutation

by Sahlin, Charlotte
Published 2007
“... addressing if and how the mutation affects APP processing. Evidence of a shift towards β-secretase cleavage...”

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Doctoral or Postdoctoral Thesis