Search Results

A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke

by Gudbjartsson, Daniel F., Holm, Hilma, Gretarsdottir, Solveig, Thorleifsson, Gudmar, Walters, G. Bragi, Thorgeirsson, Gudmundur, Gulcher, Jeffrey, Mathiesen, Ellisiv, Njølstad, Inger, Nyrnes, Audhild, Wilsgaard, Tom, Hald, Erin, Hveem, Kristian, Stoltenberg, Camilla, Kucera, Gayle, Stubblefield, Tanya, Carter, Shannon, Roden, Dan, Ng, Maggie C.Y., Baum, Larry, So, Wing Yee, Wong, Ka Sing, Chan, Juliana C. N., Gieger, Christian, Wichmann, H-Erich, Gschwendtner, Andreas, Dichgans, Martin, Kuhlenbäumer, Gregor, Berger, Klaus, Ringelstein, E. Bernd, Bevan, Steve, Markus, Hugh, Kostulas, Konstantinos, Hillert, Jan, Sveinbjörnsdóttir, Sigurlaug, Valdimarsson, Einar M., Løchen, Maja-Lisa, Ma, Ronald C. W., Darbar, Dawood, Kong, Augustine, Arnar, David O., Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2009)

Allele frequency of variants reported to cause adenine phosphoribosyltransferase deficiency

by Runolfsdottir, Hrafnhildur L., Sayer, John A., Indridason, Olafur S., Edvardsson, Vidar O., Jensson, Brynjar O., Arnadottir, Gudny A., Gudjonsson, Sigurjon A., Fridriksdottir, Run, Katrinardottir, Hildigunnur, Gudbjartsson, Daniel, Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari, Palsson, Runolfur
Published in European Journal of Human Genetics (2021)

Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank

by Olafsdottir, Thorhildur, Thorleifsson, Gudmar, Sulem, Patrick, Stefansson, Olafur A., Medek, Helga, Olafsson, Karl, Ingthorsson, Orri, Gudmundsson, Valur, Jonsdottir, Ingileif, Halldorsson, Gisli H., Kristjansson, Ragnar P., Frigge, Michael L., Stefansdottir, Lilja, Sigurdsson, Jon K., Oddsson, Asmundur, Sigurdsson, Asgeir, Eggertsson, Hannes P., Melsted, Pall, Halldorsson, Bjarni V., Lund, Sigrun H., Styrkarsdottir, Unnur, Steinthorsdottir, Valgerdur, Gudmundsson, Julius, Holm, Hilma, Tragante, Vinicius, Asselbergs, Folkert W., Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Jonsdottir, Kristin, Rafnar, Thorunn, Stefansson, Kari
Published in Communications Biology (2020)

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption

by Sulem, Patrick, Gudbjartsson, Daniel F., Geller, Frank, Prokopenko, Inga, Feenstra, Bjarke, Aben, Katja K.H., Franke, Barbara, den Heijer, Martin, Kovacs, Peter, Stumvoll, Michael, Mägi, Reedik, Yanek, Lisa R., Becker, Lewis C., Boyd, Heather A., Stacey, Simon N., Walters, G. Bragi, Jonsdottir, Adalbjorg, Thorleifsson, Gudmar, Holm, Hilma, Gudjonsson, Sigurjon A., Rafnar, Thorunn, Björnsdottir, Gyda, Becker, Diane M., Melbye, Mads, Kong, Augustine, Tönjes, Anke, Thorgeirsson, Thorgeir, Thorsteinsdottir, Unnur, Kiemeney, Lambertus A., Stefansson, Kari
Published in Human Molecular Genetics (2011)

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption

by Sulem, Patrick, Gudbjartsson, Daniel F., Geller, Frank, Prokopenko, Inga, Feenstra, Bjarke, Aben, Katja K.H., Franke, Barbara, den Heijer, Martin, Kovacs, Peter, Stumvoll, Michael, Mägi, Reedik, Yanek, Lisa R., Becker, Lewis C., Boyd, Heather A., Stacey, Simon N., Walters, G. Bragi, Jonasdottir, Adalbjorg, Thorleifsson, Gudmar, Holm, Hilma, Gudjonsson, Sigurjon A., Rafnar, Thorunn, Björnsdottir, Gyda, Becker, Diane M., Melbye, Mads, Kong, Augustine, Tönjes, Anke, Thorgeirsson, Thorgeir, Thorsteinsdottir, Unnur, Kiemeney, Lambertus A., Stefansson, Kari
Published in Human Molecular Genetics (2011)

A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease

by Arnadottir, Gudny A., Norddahl, Gudmundur L., Gudmundsdottir, Steinunn, Agustsdottir, Arna B., Sigurdsson, Snaevar, Jensson, Brynjar O., Bjarnadottir, Kristbjorg, Theodors, Fannar, Benonisdottir, Stefania, Ivarsdottir, Erna V., Oddsson, Asmundur, Kristjansson, Ragnar P., Sulem, Gerald, Alexandersson, Kristjan F., Juliusdottir, Thorhildur, Gudmundsson, Kjartan R., Saemundsdottir, Jona, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Manzanillo, Paolo, Gudjonsson, Sigurjon A., Thorisson, Gudmundur A., Magnusson, Olafur Th., Masson, Gisli, Orvar, Kjartan B., Holm, Hilma, Bjornsson, Sigurdur, Arngrimsson, Reynir, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Haraldsson, Asgeir, Sulem, Patrick, Stefansson, Kari
Published in Nature Communications (2018)

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

by Thorleifsson, Gudmar, Walters, G Bragi, Hewitt, Alex W, Masson, Gisli, Helgason, Agnar, DeWan, Andrew, Sigurdsson, Asgeir, Jonasdottir, Adalbjorg, Gudjonsson, Sigurjon A, Magnusson, Kristinn P, Stefansson, Hreinn, Lam, Dennis S C, Tam, Pancy O S, Gudmundsdottir, Gudrun J, Southgate, Laura, Burdon, Kathryn P, Gottfredsdottir, Maria Soffia, Aldred, Micheala A, Mitchell, Paul, St Clair, David, Collier, David A, Tang, Nelson, Sveinsson, Orn, Macgregor, Stuart, Martin, Nicholas G, Cree, Angela J, Gibson, Jane, MacLeod, Alex, Jacob, Aby, Ennis, Sarah, Young, Terri L, Chan, Juliana C N, Karwatowski, Wojciech S S, Hammond, Christopher J, Thordarson, Kristjan, Zhang, Mingzhi, Wadelius, Claes, Lotery, Andrew J, Trembath, Richard C, Pang, Chi Pui, Hoh, Josephine, Craig, Jamie E, Kong, Augustine, Mackey, David A, Jonasson, Fridbert, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2010)

Effect of booster vaccination against Delta and Omicron SARS-CoV-2 variants in Iceland

by Norddahl, Gudmundur L., Melsted, Pall, Gunnarsdottir, Kristbjorg, Halldorsson, Gisli H., Olafsdottir, Thorunn A., Gylfason, Arnaldur, Kristjansson, Mar, Magnusson, Olafur T., Sulem, Patrick, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Stefansson, Kari
Published in Nature Communications (2022)

Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis

by Oskarsson, Gudjon R., Oddsson, Asmundur, Magnusson, Magnus K., Kristjansson, Ragnar P., Halldorsson, Gisli H., Ferkingstad, Egil, Zink, Florian, Helgadottir, Anna, Ivarsdottir, Erna V., Arnadottir, Gudny A., Jensson, Brynjar O., Katrinardottir, Hildigunnur, Sveinbjornsson, Gardar, Kristinsdottir, Anna M., Lee, Amy L., Saemundsdottir, Jona, Stefansdottir, Lilja, Sigurdsson, Jon K., Davidsson, Olafur B., Benonisdottir, Stefania, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Jonsson, Stefan, Gudmundsson, Reynir L., Asselbergs, Folkert W., Tragante, Vinicius, Gunnarsson, Bjarni, Masson, Gisli, Thorleifsson, Gudmar, Rafnar, Thorunn, Holm, Hilma, Olafsson, Isleifur, Onundarson, Pall T., Gudbjartsson, Daniel F., Norddahl, Gudmundur L., Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published in Communications Biology (2020)

Genome-wide association meta-analysis yields 20 loci associated with gallstone disease

by Ferkingstad, Egil, Oddsson, Asmundur, Gretarsdottir, Solveig, Benonisdottir, Stefania, Thorleifsson, Gudmar, Deaton, Aimee M., Jonsson, Stefan, Stefansson, Olafur A., Norddahl, Gudmundur L., Zink, Florian, Arnadottir, Gudny A., Gunnarsson, Bjarni, Halldorsson, Gisli H., Helgadottir, Anna, Jensson, Brynjar O., Kristjansson, Ragnar P., Sveinbjornsson, Gardar, Sverrisson, David A., Masson, Gisli, Olafsson, Isleifur, Eyjolfsson, Gudmundur I., Sigurdardottir, Olof, Holm, Hilma, Jonsdottir, Ingileif, Olafsson, Sigurdur, Steingrimsdottir, Thora, Rafnar, Thorunn, Bjornsson, Einar S., Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Sulem, Patrick, Stefansson, Kari
Published in Nature Communications (2018)

Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis

by Olafsdottir, Thorunn A., Theodors, Fannar, Bjarnadottir, Kristbjorg, Bjornsdottir, Unnur Steina, Agustsdottir, Arna B., Stefansson, Olafur A., Ivarsdottir, Erna V., Sigurdsson, Jon K., Benonisdottir, Stefania, Eyjolfsson, Gudmundur I., Gislason, David, Gislason, Thorarinn, Guðmundsdóttir, Steinunn, Gylfason, Arnaldur, Halldorsson, Bjarni V., Halldorsson, Gisli H., Juliusdottir, Thorhildur, Kristinsdottir, Anna M., Ludviksdottir, Dora, Ludviksson, Bjorn R., Masson, Gisli, Norland, Kristjan, Onundarson, Pall T., Olafsson, Isleifur, Sigurdardottir, Olof, Stefansdottir, Lilja, Sveinbjornsson, Gardar, Tragante, Vinicius, Gudbjartsson, Daniel F., Thorleifsson, Gudmar, Sulem, Patrick, Thorsteinsdottir, Unnur, Norddahl, Gudmundur L., Jonsdottir, Ingileif, Stefansson, Kari
Published in Nature Communications (2020)

Genetic architecture of band neutrophil fraction in Iceland

by Oskarsson, Gudjon R., Magnusson, Magnus K., Oddsson, Asmundur, Jensson, Brynjar O., Fridriksdottir, Run, Arnadottir, Gudny A., Katrinardottir, Hildigunnur, Rognvaldsson, Solvi, Halldorsson, Gisli H., Sveinbjornsson, Gardar, Ivarsdottir, Erna V., Stefansdottir, Lilja, Ferkingstad, Egil, Norland, Kristjan, Tragante, Vinicius, Saemundsdottir, Jona, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Sigurjonsdottir, Svanhvit, Petursdottir, Karen O., Davidsson, Olafur B., Rafnar, Thorunn, Holm, Hilma, Olafsson, Isleifur, Onundarson, Pall T., Vidarsson, Brynjar, Sigurdardottir, Olof, Masson, Gisli, Gudbjartsson, Daniel F., Jonsdottir, Ingileif, Norddahl, Gudmundur L., Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published in Communications Biology (2022)

Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA

by Gudmundsson, Julius, Sigurdsson, Jon K., Stefansdottir, Lilja, Agnarsson, Bjarni A., Isaksson, Helgi J., Stefansson, Olafur A., Gudjonsson, Sigurjon A., Gudbjartsson, Daniel F., Masson, Gisli, Frigge, Michael L., Stacey, Simon N., Sulem, Patrick, Halldorsson, Gisli H., Tragante, Vinicius, Holm, Hilma, Eyjolfsson, Gudmundur I., Sigurdardottir, Olof, Olafsson, Isleifur, Jonsson, Thorvaldur, Jonsson, Eirikur, Barkardottir, Rosa B., Hilmarsson, Rafn, Asselbergs, Folkert W., Geirsson, Gudmundur, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Thorleifsson, Gudmar, Stefansson, Kari
Published in Nature Communications (2018)

The genetic architecture of age-related hearing impairment revealed by genome-wide association analysis

by Ivarsdottir, Erna V., Holm, Hilma, Benonisdottir, Stefania, Olafsdottir, Thorhildur, Sveinbjornsson, Gardar, Thorleifsson, Gudmar, Eggertsson, Hannes P., Halldorsson, Gisli H., Hjorleifsson, Kristjan E., Melsted, Pall, Gylfason, Arnaldur, Arnadottir, Gudny A., Oddsson, Asmundur, Jensson, Brynjar O., Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Juliusdottir, Thorhildur, Stefansdottir, Lilja, Tragante, Vinicius, Halldorsson, Bjarni V., Petersen, Hannes, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Sulem, Patrick, Hinriksdottir, Ingibjorg, Jonsdottir, Ingileif, Gudbjartsson, Daniel F., Stefansson, Kari
Published in Communications Biology (2021)

Physical and neuro-behavioural determinants of reproductive onset and success

by Day, Felix R., Helgason, Hannes, Chasman, Daniel I., Rose, Lynda M., Loh, Po-Ru, Scott, Robert A., Helgason, Agnar, Kong, Augustine, Masson, Gisli, Magnusson, Olafur Th., Gudbjartsson, Daniel, Thorsteinsdottir, Unnur, Buring, Julie E., Ridker, Paul M., Sulem, Patrick, Stefansson, Kari, Ong, Ken K., Perry, John R.B.
Published in Nature Genetics (2016)

A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis

by Bell, Steven, Rigas, Andreas S., Magnusson, Magnus K., Ferkingstad, Egil, Allara, Elias, Bjornsdottir, Gyda, Ramond, Anna, Sørensen, Erik, Halldorsson, Gisli H., Paul, Dirk S., Burgdorf, Kristoffer S., Eggertsson, Hannes P., Howson, Joanna M. M., Thørner, Lise W., Kristmundsdottir, Snaedis, Astle, William J., Erikstrup, Christian, Sigurdsson, Jon K., Vuckovic, Dragana, Dinh, Khoa M., Tragante, Vinicius, Surendran, Praveen, Pedersen, Ole B., Vidarsson, Brynjar, Jiang, Tao, Paarup, Helene M., Onundarson, Pall T., Akbari, Parsa, Nielsen, Kaspar R., Lund, Sigrun H., Juliusson, Kristinn, Magnusson, Magnus I., Frigge, Michael L., Oddsson, Asmundur, Olafsson, Isleifur, Kaptoge, Stephen, Hjalgrim, Henrik, Runarsson, Gudmundur, Wood, Angela M., Jonsdottir, Ingileif, Hansen, Thomas F., Sigurdardottir, Olof, Stefansson, Hreinn, Rye, David, Peters, James E., Westergaard, David, Holm, Hilma, Soranzo, Nicole, Banasik, Karina, Thorleifsson, Gudmar, Ouwehand, Willem H., Thorsteinsdottir, Unnur, Roberts, David J., Sulem, Patrick, Butterworth, Adam S., Gudbjartsson, Daniel F., Danesh, John, Brunak, Søren, Di Angelantonio, Emanuele, Ullum, Henrik, Stefansson, Kari, Andersen, Steffen, Burgdorf, Kristoffer, Jemec, Gregor, Jennum, Poul, Johansson, Pär, Nielsen, Kasper R., Nyegaard, Mette, Petersen, Mikkel, Werge, Thomas, Stefánsson, Hreinn, Thorsteinsdóttir, Unnur
Published 2021

Molecular benchmarks of a SARS-CoV-2 epidemic

by Jonsson, Hakon, Magnusson, Olafur T., Melsted, Pall, Berglund, Jonas, Agustsdottir, Arna B., Eiríksdottir, Berglind, Fridriksdottir, Run, Garðarsdottir, Elisabet Eir, Georgsson, Gudmundur, Gretarsdottir, Olafia S., Guðmundsson, Kjartan R., Gunnarsdottir, Thora Rosa, Eggertsson, Hannes, Gylfason, Arnaldur, Holm, Hilma, Jensson, Brynjar O., Jonasdottir, Aslaug, Jonsson, Frosti, Josefsdottir, Kamilla S., Thordardottir, Marianna, Kristinsson, Karl G., Kristjánsson, Þórður, Magnusdottir, Droplaug N., Roux, Louise le, Saemundsdottir, Jona, Sigurdsson, Asgeir, Sigmundsdottir, Gudrun, Sveinbjornsson, Gardar, Rognvaldsson, Solvi, Eiriksson, Ogmundur, Magnusson, Magnus Karl, Sveinsdottir, Kristin Eva, Sveinsdottir, Maney, Thorarensen, Emil Aron, Thorbjornsson, Bjarni, Löve, Arthur, Norddahl, Gudmundur L., Jonsdottir, Ingileif, Sulem, Patrick, Masson, Gisli, Moller, Alma, Gudnason, Thorolfur, Kristjansson, Mar, Helgason, Agnar, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Communications (2021)

Genetic correction of PSA values using sequence variants associated with PSA levels

by Gudmundsson, Julius, Besenbacher, Soren, Sulem, Patrick, Gudbjartsson, Daniel F., Olafsson, Isleifur, Arinbjarnarson, Sturla, Agnarsson, Bjarni A., Benediktsdottir, Kristrun R., Isaksson, Helgi J., Kostic, Jelena P., Gudjonsson, Sigurjon A., Stacey, Simon N., Gylfason, Arnaldur, Sigurdsson, Asgeir, Holm, Hilma, Bjornsdottir, Unnur S., Eyjolfsson, Gudmundur I., Navarrete, Sebastian, Fuertes, Fernando, Garcia-Prats, Maria D., Polo, Eduardo, Checherita, Ionel A., Jinga, Mariana, Badea, Paula, Aben, Katja K., Schalken, Jack A., van Oort, Inge M., Sweep, Fred C., Helfand, Brian T., Davis, Michael, Donovan, Jenny L., Hamdy, Freddie C., Kristjansson, Kristleifur, Gulcher, Jeffrey R., Masson, Gisli, Kong, Augustine, Catalona, William J., Mayordomo, Jose I., Geirsson, Gudmundur, Einarsson, Gudmundur V., Barkardottir, Rosa B., Jonsson, Eirikur, Jinga, Viorel, Mates, Dana, Kiemeney, Lambertus A., Neal, David E., Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Science Translational Medicine (2010)

Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk

by Rafnar, Thorunn, Sulem, Patrick, Besenbacher, Soren, Gudbjartsson, Daniel F., Zanon, Carlo, Gudmundsson, Julius, Stacey, Simon N., Kostic, Jelena P., Thorgeirsson, Thorgeir E., Thorleifsson, Gudmar, Bjarnason, Hjordis, Skuladottir, Halla, Gudbjartsson, Tomas, Isaksson, Helgi J., Isla, Dolores, Murillo, Laura, García-Prats, Maria D., Panadero, Angeles, Aben, Katja K.H., Vermeulen, Sita H., van der Heijden, Henricus F.M., Feser, William, Miller, York E., Bunn, Paul A., Kong, Augustine, Wolf, Holly J., Franklin, Wilbur A., Mayordomo, Jose I, Kiemeney, Lambertus A., Jonsson, Steinn, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Cancer Research (2011)

Sequence variants in malignant hyperthermia genes in Iceland: classification and actionable findings in a population database

by Fridriksdottir, Run, Jonsson, Arnar J., Jensson, Brynjar O., Sverrisson, Kristinn O., Arnadottir, Gudny A., Skarphedinsdottir, Sigurbjorg J., Katrinardottir, Hildigunnur, Snaebjornsdottir, Steinunn, Jonsson, Hakon, Eiriksson, Ogmundur, Oskarsson, Gudjon R., Oddsson, Asmundur, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Gisli H., Indridason, Einar P., Sigurdsson, Stefan B., Bjornsdottir, Gyda, Saemundsdottir, Jona, Magnusson, Olafur T., Bjornsson, Hans T., Thorsteinsdottir, Unnur, Sigurdsson, Theodor S., Sulem, Patrick, Sigurdsson, Martin I., Stefansson, Kari
Published in European Journal of Human Genetics (2021)