Search Results

Allele frequency of variants reported to cause adenine phosphoribosyltransferase deficiency

by Runolfsdottir, Hrafnhildur L., Sayer, John A., Indridason, Olafur S., Edvardsson, Vidar O., Jensson, Brynjar O., Arnadottir, Gudny A., Gudjonsson, Sigurjon A., Fridriksdottir, Run, Katrinardottir, Hildigunnur, Gudbjartsson, Daniel, Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari, Palsson, Runolfur
Published in European Journal of Human Genetics (2021)

Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2

by Haraldsdottir, Sigurdis, Rafnar, Thorunn, Frankel, Wendy L., Einarsdottir, Sylvia, Sigurdsson, Asgeir, Hampel, Heather, Snaebjornsson, Petur, Masson, Gisli, Weng, Daniel, Arngrimsson, Reynir, Kehr, Birte, Yilmaz, Ahmet, Haraldsson, Stefan, Sulem, Patrick, Stefansson, Tryggvi, Shields, Peter G., Sigurdsson, Fridbjorn, Bekaii-Saab, Tanios, Moller, Pall H., Steinarsdottir, Margret, Alexiusdottir, Kristin, Hitchins, Megan, Pritchard, Colin C., de la Chapelle, Albert, Jonasson, Jon G., Goldberg, Richard M., Stefansson, Kari
Published in Nature Communications (2017)

Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank

by Olafsdottir, Thorhildur, Thorleifsson, Gudmar, Sulem, Patrick, Stefansson, Olafur A., Medek, Helga, Olafsson, Karl, Ingthorsson, Orri, Gudmundsson, Valur, Jonsdottir, Ingileif, Halldorsson, Gisli H., Kristjansson, Ragnar P., Frigge, Michael L., Stefansdottir, Lilja, Sigurdsson, Jon K., Oddsson, Asmundur, Sigurdsson, Asgeir, Eggertsson, Hannes P., Melsted, Pall, Halldorsson, Bjarni V., Lund, Sigrun H., Styrkarsdottir, Unnur, Steinthorsdottir, Valgerdur, Gudmundsson, Julius, Holm, Hilma, Tragante, Vinicius, Asselbergs, Folkert W., Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Jonsdottir, Kristin, Rafnar, Thorunn, Stefansson, Kari
Published in Communications Biology (2020)

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption

by Sulem, Patrick, Gudbjartsson, Daniel F., Geller, Frank, Prokopenko, Inga, Feenstra, Bjarke, Aben, Katja K.H., Franke, Barbara, den Heijer, Martin, Kovacs, Peter, Stumvoll, Michael, Mägi, Reedik, Yanek, Lisa R., Becker, Lewis C., Boyd, Heather A., Stacey, Simon N., Walters, G. Bragi, Jonsdottir, Adalbjorg, Thorleifsson, Gudmar, Holm, Hilma, Gudjonsson, Sigurjon A., Rafnar, Thorunn, Björnsdottir, Gyda, Becker, Diane M., Melbye, Mads, Kong, Augustine, Tönjes, Anke, Thorgeirsson, Thorgeir, Thorsteinsdottir, Unnur, Kiemeney, Lambertus A., Stefansson, Kari
Published in Human Molecular Genetics (2011)

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption

by Sulem, Patrick, Gudbjartsson, Daniel F., Geller, Frank, Prokopenko, Inga, Feenstra, Bjarke, Aben, Katja K.H., Franke, Barbara, den Heijer, Martin, Kovacs, Peter, Stumvoll, Michael, Mägi, Reedik, Yanek, Lisa R., Becker, Lewis C., Boyd, Heather A., Stacey, Simon N., Walters, G. Bragi, Jonasdottir, Adalbjorg, Thorleifsson, Gudmar, Holm, Hilma, Gudjonsson, Sigurjon A., Rafnar, Thorunn, Björnsdottir, Gyda, Becker, Diane M., Melbye, Mads, Kong, Augustine, Tönjes, Anke, Thorgeirsson, Thorgeir, Thorsteinsdottir, Unnur, Kiemeney, Lambertus A., Stefansson, Kari
Published in Human Molecular Genetics (2011)

A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease

by Arnadottir, Gudny A., Norddahl, Gudmundur L., Gudmundsdottir, Steinunn, Agustsdottir, Arna B., Sigurdsson, Snaevar, Jensson, Brynjar O., Bjarnadottir, Kristbjorg, Theodors, Fannar, Benonisdottir, Stefania, Ivarsdottir, Erna V., Oddsson, Asmundur, Kristjansson, Ragnar P., Sulem, Gerald, Alexandersson, Kristjan F., Juliusdottir, Thorhildur, Gudmundsson, Kjartan R., Saemundsdottir, Jona, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Manzanillo, Paolo, Gudjonsson, Sigurjon A., Thorisson, Gudmundur A., Magnusson, Olafur Th., Masson, Gisli, Orvar, Kjartan B., Holm, Hilma, Bjornsson, Sigurdur, Arngrimsson, Reynir, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Haraldsson, Asgeir, Sulem, Patrick, Stefansson, Kari
Published in Nature Communications (2018)

Sequence variant on 8q24 confers susceptibility to urinary bladder cancer

by Kiemeney, Lambertus A., Thorlacius, Steinunn, Sulem, Patrick, Geller, Frank, Aben, Katja K.H., Stacey, Simon N., Gudmundsson, Julius, Jakobsdottir, Margret, Bergthorsson, Jon T., Sigurdsson, Asgeir, Blondal, Thorarinn, Witjes, J. Alfred, Vermeulen, Sita H., Hulsbergen-van de Kaa, Christina A., Swinkels, Dorine W., Ploeg, Martine, Cornel, Erik B., Vergunst, Henk, Thorgeirsson, Thorgeir E., Gudbjartsson, Daniel, Gudjonsson, Sigurjon A., Thorleifsson, Gudmar, Kristinsson, Kari T., Mouy, Magali, Snorradottir, Steinunn, Placidi, Donatella, Campagna, Marcello, Arici, Cecilia, Koppova, Kvetoslava, Gurzau, Eugene, Rudnai, Peter, Kellen, Eliane, Polidoro, Silvia, Guarrera, Simonetta, Sacerdote, Carlotta, Sanchez, Manuel, Saez, Berta, Valdivia, Gabriel, Ryk, Charlotta, de Verdier, Petra, Lindblom, Annika, Golka, Klaus, Bishop, D. Timothy, Knowles, Margaret A., Nikulasson, Sigfus, Petursdottir, Vigdis, Jonsson, Eirikur, Geirsson, Gudmundur, Kristjansson, Baldvin, Mayordomo, Jose I.
Published in Nature Genetics (2008)

Effect of booster vaccination against Delta and Omicron SARS-CoV-2 variants in Iceland

by Norddahl, Gudmundur L., Melsted, Pall, Gunnarsdottir, Kristbjorg, Halldorsson, Gisli H., Olafsdottir, Thorunn A., Gylfason, Arnaldur, Kristjansson, Mar, Magnusson, Olafur T., Sulem, Patrick, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Stefansson, Kari
Published in Nature Communications (2022)

Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis

by Oskarsson, Gudjon R., Oddsson, Asmundur, Magnusson, Magnus K., Kristjansson, Ragnar P., Halldorsson, Gisli H., Ferkingstad, Egil, Zink, Florian, Helgadottir, Anna, Ivarsdottir, Erna V., Arnadottir, Gudny A., Jensson, Brynjar O., Katrinardottir, Hildigunnur, Sveinbjornsson, Gardar, Kristinsdottir, Anna M., Lee, Amy L., Saemundsdottir, Jona, Stefansdottir, Lilja, Sigurdsson, Jon K., Davidsson, Olafur B., Benonisdottir, Stefania, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Jonsson, Stefan, Gudmundsson, Reynir L., Asselbergs, Folkert W., Tragante, Vinicius, Gunnarsson, Bjarni, Masson, Gisli, Thorleifsson, Gudmar, Rafnar, Thorunn, Holm, Hilma, Olafsson, Isleifur, Onundarson, Pall T., Gudbjartsson, Daniel F., Norddahl, Gudmundur L., Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published in Communications Biology (2020)

Genome-wide association meta-analysis yields 20 loci associated with gallstone disease

by Ferkingstad, Egil, Oddsson, Asmundur, Gretarsdottir, Solveig, Benonisdottir, Stefania, Thorleifsson, Gudmar, Deaton, Aimee M., Jonsson, Stefan, Stefansson, Olafur A., Norddahl, Gudmundur L., Zink, Florian, Arnadottir, Gudny A., Gunnarsson, Bjarni, Halldorsson, Gisli H., Helgadottir, Anna, Jensson, Brynjar O., Kristjansson, Ragnar P., Sveinbjornsson, Gardar, Sverrisson, David A., Masson, Gisli, Olafsson, Isleifur, Eyjolfsson, Gudmundur I., Sigurdardottir, Olof, Holm, Hilma, Jonsdottir, Ingileif, Olafsson, Sigurdur, Steingrimsdottir, Thora, Rafnar, Thorunn, Bjornsson, Einar S., Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Sulem, Patrick, Stefansson, Kari
Published in Nature Communications (2018)

Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis

by Olafsdottir, Thorunn A., Theodors, Fannar, Bjarnadottir, Kristbjorg, Bjornsdottir, Unnur Steina, Agustsdottir, Arna B., Stefansson, Olafur A., Ivarsdottir, Erna V., Sigurdsson, Jon K., Benonisdottir, Stefania, Eyjolfsson, Gudmundur I., Gislason, David, Gislason, Thorarinn, Guðmundsdóttir, Steinunn, Gylfason, Arnaldur, Halldorsson, Bjarni V., Halldorsson, Gisli H., Juliusdottir, Thorhildur, Kristinsdottir, Anna M., Ludviksdottir, Dora, Ludviksson, Bjorn R., Masson, Gisli, Norland, Kristjan, Onundarson, Pall T., Olafsson, Isleifur, Sigurdardottir, Olof, Stefansdottir, Lilja, Sveinbjornsson, Gardar, Tragante, Vinicius, Gudbjartsson, Daniel F., Thorleifsson, Gudmar, Sulem, Patrick, Thorsteinsdottir, Unnur, Norddahl, Gudmundur L., Jonsdottir, Ingileif, Stefansson, Kari
Published in Nature Communications (2020)

Genetic architecture of band neutrophil fraction in Iceland

by Oskarsson, Gudjon R., Magnusson, Magnus K., Oddsson, Asmundur, Jensson, Brynjar O., Fridriksdottir, Run, Arnadottir, Gudny A., Katrinardottir, Hildigunnur, Rognvaldsson, Solvi, Halldorsson, Gisli H., Sveinbjornsson, Gardar, Ivarsdottir, Erna V., Stefansdottir, Lilja, Ferkingstad, Egil, Norland, Kristjan, Tragante, Vinicius, Saemundsdottir, Jona, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Sigurjonsdottir, Svanhvit, Petursdottir, Karen O., Davidsson, Olafur B., Rafnar, Thorunn, Holm, Hilma, Olafsson, Isleifur, Onundarson, Pall T., Vidarsson, Brynjar, Sigurdardottir, Olof, Masson, Gisli, Gudbjartsson, Daniel F., Jonsdottir, Ingileif, Norddahl, Gudmundur L., Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published in Communications Biology (2022)

Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA

by Gudmundsson, Julius, Sigurdsson, Jon K., Stefansdottir, Lilja, Agnarsson, Bjarni A., Isaksson, Helgi J., Stefansson, Olafur A., Gudjonsson, Sigurjon A., Gudbjartsson, Daniel F., Masson, Gisli, Frigge, Michael L., Stacey, Simon N., Sulem, Patrick, Halldorsson, Gisli H., Tragante, Vinicius, Holm, Hilma, Eyjolfsson, Gudmundur I., Sigurdardottir, Olof, Olafsson, Isleifur, Jonsson, Thorvaldur, Jonsson, Eirikur, Barkardottir, Rosa B., Hilmarsson, Rafn, Asselbergs, Folkert W., Geirsson, Gudmundur, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Thorleifsson, Gudmar, Stefansson, Kari
Published in Nature Communications (2018)

The genetic architecture of age-related hearing impairment revealed by genome-wide association analysis

by Ivarsdottir, Erna V., Holm, Hilma, Benonisdottir, Stefania, Olafsdottir, Thorhildur, Sveinbjornsson, Gardar, Thorleifsson, Gudmar, Eggertsson, Hannes P., Halldorsson, Gisli H., Hjorleifsson, Kristjan E., Melsted, Pall, Gylfason, Arnaldur, Arnadottir, Gudny A., Oddsson, Asmundur, Jensson, Brynjar O., Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Juliusdottir, Thorhildur, Stefansdottir, Lilja, Tragante, Vinicius, Halldorsson, Bjarni V., Petersen, Hannes, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Sulem, Patrick, Hinriksdottir, Ingibjorg, Jonsdottir, Ingileif, Gudbjartsson, Daniel F., Stefansson, Kari
Published in Communications Biology (2021)

Physical and neuro-behavioural determinants of reproductive onset and success

by Day, Felix R., Helgason, Hannes, Chasman, Daniel I., Rose, Lynda M., Loh, Po-Ru, Scott, Robert A., Helgason, Agnar, Kong, Augustine, Masson, Gisli, Magnusson, Olafur Th., Gudbjartsson, Daniel, Thorsteinsdottir, Unnur, Buring, Julie E., Ridker, Paul M., Sulem, Patrick, Stefansson, Kari, Ong, Ken K., Perry, John R.B.
Published in Nature Genetics (2016)

European Genome-Wide Association Study Identifies SLC14A1 as a New Urinary Bladder Cancer Susceptibility Gene

by Rafnar, Thorunn, Vermeulen, Sita H., Sulem, Patrick, Thorleifsson, Gudmar, Aben, Katja K., Witjes, J. Alfred, Grotenhuis, Anne J., Verhaegh, Gerald W., Hulsbergen-van de Kaa, Christina A., Besenbacher, Soren, Gudbjartsson, Daniel, Stacey, Simon N., Gudmundsson, Julius, Johannsdottir, Hrefna, Bjarnason, Hjordis, Zanon, Carlo, Helgadottir, Hafdis, Jonasson, Jon Gunnlaugur, Tryggvadottir, Laufey, Jonsson, Eirikur, Geirsson, Gudmundur, Nikulasson, Sigfus, Petursdottir, Vigdis, Bishop, D. Timothy, Chung-Sak, Sei, Choudhury, Ananya, Elliott, Faye, Barrett, Jennifer H., Knowles, Margaret A., de Verdier, Petra J., Ryk, Charlotta, Lindblom, Annika, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, Vineis, Paolo, Polidoro, Silvia, Guarrera, Simonetta, Sacerdote, Carlotta, Panadero, Angeles, Sanz-Velez, José I., Sanchez, Manuel, Valdivia, Gabriel, Garcia-Prats, Maria D., Hengstler, Jan G., Selinski, Silvia, Gerullis, Holger, Ovsiannikov, Daniel, Khezri, Abdolaziz, Aminsharifi, Alireza
Published in Human Molecular Genetics (2011)

European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene

by Rafnar, Thorunn, Vermeulen, Sita H., Sulem, Patrick, Thorleifsson, Gudmar, Aben, Katja K., Witjes, J. Alfred, Grotenhuis, Anne J., Verhaegh, Gerald W., Hulsbergen-van de Kaa, Christina A., Besenbacher, Soren, Gudbjartsson, Daniel, Stacey, Simon N., Gudmundsson, Julius, Johannsdottir, Hrefna, Bjarnason, Hjordis, Zanon, Carlo, Helgadottir, Hafdis, Jonasson, Jon Gunnlaugur, Tryggvadottir, Laufey, Jonsson, Eirikur, Geirsson, Gudmundur, Nikulasson, Sigfus, Petursdottir, Vigdis, Bishop, D. Timothy, Chung-Sak, Sei, Choudhury, Ananya, Elliott, Faye, Barrett, Jennifer H., Knowles, Margaret A., de Verdier, Petra J., Ryk, Charlotta, Lindblom, Annika, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, Vineis, Paolo, Polidoro, Silvia, Guarrera, Simonetta, Sacerdote, Carlotta, Panadero, Angeles, Sanz-Velez, José I., Sanchez, Manuel, Valdivia, Gabriel, Garcia-Prats, Maria D., Hengstler, Jan G., Selinski, Silvia, Gerullis, Holger, Ovsiannikov, Daniel, Khezri, Abdolaziz, Aminsharifi, Alireza
Published in Human Molecular Genetics (2011)

A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis

by Bell, Steven, Rigas, Andreas S., Magnusson, Magnus K., Ferkingstad, Egil, Allara, Elias, Bjornsdottir, Gyda, Ramond, Anna, Sørensen, Erik, Halldorsson, Gisli H., Paul, Dirk S., Burgdorf, Kristoffer S., Eggertsson, Hannes P., Howson, Joanna M. M., Thørner, Lise W., Kristmundsdottir, Snaedis, Astle, William J., Erikstrup, Christian, Sigurdsson, Jon K., Vuckovic, Dragana, Dinh, Khoa M., Tragante, Vinicius, Surendran, Praveen, Pedersen, Ole B., Vidarsson, Brynjar, Jiang, Tao, Paarup, Helene M., Onundarson, Pall T., Akbari, Parsa, Nielsen, Kaspar R., Lund, Sigrun H., Juliusson, Kristinn, Magnusson, Magnus I., Frigge, Michael L., Oddsson, Asmundur, Olafsson, Isleifur, Kaptoge, Stephen, Hjalgrim, Henrik, Runarsson, Gudmundur, Wood, Angela M., Jonsdottir, Ingileif, Hansen, Thomas F., Sigurdardottir, Olof, Stefansson, Hreinn, Rye, David, Peters, James E., Westergaard, David, Holm, Hilma, Soranzo, Nicole, Banasik, Karina, Thorleifsson, Gudmar, Ouwehand, Willem H., Thorsteinsdottir, Unnur, Roberts, David J., Sulem, Patrick, Butterworth, Adam S., Gudbjartsson, Daniel F., Danesh, John, Brunak, Søren, Di Angelantonio, Emanuele, Ullum, Henrik, Stefansson, Kari, Andersen, Steffen, Burgdorf, Kristoffer, Jemec, Gregor, Jennum, Poul, Johansson, Pär, Nielsen, Kasper R., Nyegaard, Mette, Petersen, Mikkel, Werge, Thomas, Stefánsson, Hreinn, Thorsteinsdóttir, Unnur
Published 2021

Molecular benchmarks of a SARS-CoV-2 epidemic

by Jonsson, Hakon, Magnusson, Olafur T., Melsted, Pall, Berglund, Jonas, Agustsdottir, Arna B., Eiríksdottir, Berglind, Fridriksdottir, Run, Garðarsdottir, Elisabet Eir, Georgsson, Gudmundur, Gretarsdottir, Olafia S., Guðmundsson, Kjartan R., Gunnarsdottir, Thora Rosa, Eggertsson, Hannes, Gylfason, Arnaldur, Holm, Hilma, Jensson, Brynjar O., Jonasdottir, Aslaug, Jonsson, Frosti, Josefsdottir, Kamilla S., Thordardottir, Marianna, Kristinsson, Karl G., Kristjánsson, Þórður, Magnusdottir, Droplaug N., Roux, Louise le, Saemundsdottir, Jona, Sigurdsson, Asgeir, Sigmundsdottir, Gudrun, Sveinbjornsson, Gardar, Rognvaldsson, Solvi, Eiriksson, Ogmundur, Magnusson, Magnus Karl, Sveinsdottir, Kristin Eva, Sveinsdottir, Maney, Thorarensen, Emil Aron, Thorbjornsson, Bjarni, Löve, Arthur, Norddahl, Gudmundur L., Jonsdottir, Ingileif, Sulem, Patrick, Masson, Gisli, Moller, Alma, Gudnason, Thorolfur, Kristjansson, Mar, Helgason, Agnar, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Communications (2021)

Genetic correction of PSA values using sequence variants associated with PSA levels

by Gudmundsson, Julius, Besenbacher, Soren, Sulem, Patrick, Gudbjartsson, Daniel F., Olafsson, Isleifur, Arinbjarnarson, Sturla, Agnarsson, Bjarni A., Benediktsdottir, Kristrun R., Isaksson, Helgi J., Kostic, Jelena P., Gudjonsson, Sigurjon A., Stacey, Simon N., Gylfason, Arnaldur, Sigurdsson, Asgeir, Holm, Hilma, Bjornsdottir, Unnur S., Eyjolfsson, Gudmundur I., Navarrete, Sebastian, Fuertes, Fernando, Garcia-Prats, Maria D., Polo, Eduardo, Checherita, Ionel A., Jinga, Mariana, Badea, Paula, Aben, Katja K., Schalken, Jack A., van Oort, Inge M., Sweep, Fred C., Helfand, Brian T., Davis, Michael, Donovan, Jenny L., Hamdy, Freddie C., Kristjansson, Kristleifur, Gulcher, Jeffrey R., Masson, Gisli, Kong, Augustine, Catalona, William J., Mayordomo, Jose I., Geirsson, Gudmundur, Einarsson, Gudmundur V., Barkardottir, Rosa B., Jonsson, Eirikur, Jinga, Viorel, Mates, Dana, Kiemeney, Lambertus A., Neal, David E., Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Science Translational Medicine (2010)