Search Results

Large-scale whole-genome sequencing of the Icelandic population

by Gudbjartsson, Daniel F, Helgason, Hannes, Gudjonsson, Sigurjon A, Zink, Florian, Oddson, Asmundur, Gylfason, Arnaldur, Besenbacher, Soren, Magnusson, Gisli, Halldorsson, Bjarni V, Hjartarson, Eirikur, Sigurdsson, Gunnar Th, Stacey, Simon N, Frigge, Michael L, Holm, Hilma, Saemundsdottir, Jona, Helgadottir, Hafdis Th, Johannsdottir, Hrefna, Sigfusson, Gunnlaugur, Thorgeirsson, Gudmundur, Sverrisson, Jon Th, Gretarsdottir, Solveig, Walters, G Bragi, Rafnar, Thorunn, Thjodleifsson, Bjarni, Bjornsson, Einar S, Olafsson, Sigurdur, Thorarinsdottir, Hildur, Steingrimsdottir, Thora, Gudmundsdottir, Thora S, Theodors, Asgeir, Jonasson, Jon G, Sigurdsson, Asgeir, Bjornsdottir, Gyda, Jonsson, Jon J, Thorarensen, Olafur, Ludvigsson, Petur, Gudbjartsson, Hakon, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Arnar, David O, Magnusson, Olafur Th, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Sulem, Patrick, Stefansson, Kari
Published in Nature Genetics (2015)

Multiple genetic loci for bone mineral density and fractures

by Styrkarsdottir, Unnur, Halldorsson, Bjarni V, Gretarsdottir, Solveig, Gudbjartsson, Daniel F, Walters, G Bragi, Ingvarsson, Thorvaldur, Jonsdottir, Thorbjorg, Saemundsdottir, Jona, Center, Jacqueline R, Nguyen, Tuan V, Bagger, Yu, Gulcher, Jeffrey R, Eisman, John A, Christiansen, Claus, Sigurdsson, Gunnar, Kong, Augustine, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in New England Journal of Medicine (2009)

Large-scale whole-genome sequencing of the Icelandic population.

by Gudbjartsson, Daniel F, Helgason, Hannes, Gudjonsson, Sigurjon A, Zink, Florian, Oddson, Asmundur, Gylfason, Arnaldur, Besenbacher, Soren, Magnusson, Gisli, Halldorsson, Bjarni V, Hjartarson, Eirikur, Sigurdsson, Gunnar Th, Stacey, Simon N, Frigge, Michael L, Holm, Hilma, Saemundsdottir, Jona, Helgadottir, Hafdis Th, Johannsdottir, Hrefna, Sigfusson, Gunnlaugur, Thorgeirsson, Gudmundur, Sverrisson, Jon Th, Gretarsdottir, Solveig, Walters, G Bragi, Rafnar, Thorunn, Thjodleifsson, Bjarni, Bjornsson, Einar S, Olafsson, Sigurdur, Thorarinsdottir, Hildur, Steingrimsdottir, Thora, Gudmundsdottir, Thora S, Theodors, Asgeir, Jonasson, Jon G, Sigurdsson, Asgeir, Bjornsdottir, Gyda, Jonsson, Jon J, Thorarensen, Olafur, Ludvigsson, Petur, Gudbjartsson, Hakon, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Arnar, David O, Magnusson, Olafur Th, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Sulem, Patrick, Stefansson, Kari
Published in Nature Genetics (2015)

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

by Thorleifsson, Gudmar, Walters, G Bragi, Hewitt, Alex W, Masson, Gisli, Helgason, Agnar, DeWan, Andrew, Sigurdsson, Asgeir, Jonasdottir, Adalbjorg, Gudjonsson, Sigurjon A, Magnusson, Kristinn P, Stefansson, Hreinn, Lam, Dennis S C, Tam, Pancy O S, Gudmundsdottir, Gudrun J, Southgate, Laura, Burdon, Kathryn P, Gottfredsdottir, Maria Soffia, Aldred, Micheala A, Mitchell, Paul, St Clair, David, Collier, David, Tang, Nelson, Sveinsson, Orn, Macgregor, Stuart, Martin, Nicholas G, Cree, Angela J, Gibson, Jane, Macleod, Alex, Jacob, Aby, Ennis, Sarah, Young, Terri L, Chan, Juliana C N, Karwatowski, Wojciech S S, Hammond, Christopher J, Thordarson, Kristjan, Zhang, Mingzhi, Wadelius, Claes, Lotery, Andrew J, Trembath, Richard C, Pang, Chi Pui, Hoh, Josephine, Craig, Jamie E, Kong, Augustine, Mackey, David A, Jonasson, Fridbert, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2010)

Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk

by Rafnar, Thorunn, Sulem, Patrick, Besenbacher, Soren, Gudbjartsson, Daniel F, Zanon, Carlo, Gudmundsson, Julius, Stacey, Simon N, Kostic, Jelena P, Thorgeirsson, Thorgeir E, Thorleifsson, Gudmar, Bjarnason, Hjordis, Skuladottir, Halla, Gudbjartsson, Tomas, Isaksson, Helgi J, Isla, Dolores, Murillo, Laura, García-Prats, Maria D, Panadero, Angeles, Aben, Katja K H, Vermeulen, Sita H, van der Heijden, Henricus F M, Feser, William J, Miller, York E, Bunn, Paul A, Kong, Augustine, Wolf, Holly J, Franklin, Wilbur A, Mayordomo, Jose I, Kiemeney, Lambertus A, Jonsson, Steinn, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Cancer Research (2011)

Variant of TREM2 associated with the risk of Alzheimer's disease.

by Jonsson, Thorlakur, Stefansson, Hreinn, Steinberg, Stacy, Jonsdottir, Ingileif, Jonsson, Palmi V, Snaedal, Jon, Bjornsson, Sigurbjorn, Huttenlocher, Johanna, Levey, Allan I, Lah, James J, Rujescu, Dan, Hampel, Harald, Giegling, Ina, Andreassen, Ole A, Engedal, Knut, Ulstein, Ingun, Djurovic, Srdjan, Ibrahim-Verbaas, Carla, Hofman, Albert, Ikram, M Arfan, van Duijn, Cornelia M, Thorsteinsdottir, Unnur, Kong, Augustine, Stefansson, Kari
Published in New England Journal of Medicine (2013)

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

by Thorleifsson, Gudmar, Walters, G Bragi, Hewitt, Alex W, Masson, Gisli, Helgason, Agnar, DeWan, Andrew, Sigurdsson, Asgeir, Jonasdottir, Adalbjorg, Gudjonsson, Sigurjon A, Magnusson, Kristinn P, Stefansson, Hreinn, Lam, Dennis S C, Tam, Pancy O S, Gudmundsdottir, Gudrun J, Southgate, Laura, Burdon, Kathryn P, Gottfredsdottir, Maria Soffia, Aldred, Micheala A, Mitchell, Paul, St Clair, David, Collier, David A, Tang, Nelson, Sveinsson, Orn, Macgregor, Stuart, Martin, Nicholas G, Cree, Angela J, Gibson, Jane, Macleod, Alex, Jacob, Aby, Ennis, Sarah, Young, Terri L, Chan, Juliana C N, Karwatowski, Wojciech S S, Hammond, Christopher J, Thordarson, Kristjan, Zhang, Mingzhi, Wadelius, Claes, Lotery, Andrew J, Trembath, Richard C, Pang, Chi Pui, Hoh, Josephine, Craig, Jamie E, Kong, Augustine, Mackey, David A, Jonasson, Fridbert, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2010)

Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density.

by Thorleifsson, Gudmar, Holm, Hilma, Edvardsson, Vidar, Walters, G Bragi, Styrkarsdottir, Unnur, Gudbjartsson, Daniel F, Sulem, Patrick, Halldorsson, Bjarni V, de Vegt, Femmie, d'Ancona, Frank C H, den Heijer, Martin, Franzson, Leifur, Christiansen, Claus, Alexandersen, Peter, Rafnar, Thorunn, Kristjansson, Kristleifur, Sigurdsson, Gunnar, Kiemeney, Lambertus A, Bodvarsson, Magnus, Indridason, Olafur S, Palsson, Runolfur, Kong, Augustine, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2009)

A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer.

by Gudmundsson, Julius, Sulem, Patrick, Gudbjartsson, Daniel F, Masson, Gisli, Agnarsson, Bjarni A, Benediktsdottir, Kristrun R, Sigurdsson, Asgeir, Magnusson, Olafur Th, Gudjonsson, Sigurjon A, Magnusdottir, Droplaug N, Johannsdottir, Hrefna, Helgadottir, Hafdis Th, Stacey, Simon N, Jonasdottir, Adalbjorg, Olafsdottir, Stefania B, Thorleifsson, Gudmar, Jonasson, Jon G, Tryggvadottir, Laufey, Navarrete, Sebastian, Fuertes, Fernando, Helfand, Brian T, Hu, Qiaoyan, Csiki, Irma E, Mates, Ioan N, Jinga, Viorel, Aben, Katja K H, van Oort, Inge M, Vermeulen, Sita H, Donovan, Jenny L, Hamdy, Freddy C, Ng, Chi-Fai, Chiu, Peter K F, Lau, Kin-Mang, Ng, Maggie C Y, Gulcher, Jeffrey R, Kong, Augustine, Catalona, William J, Mayordomo, Jose I, Einarsson, Gudmundur V, Barkardottir, Rosa B, Jonsson, Eirikur, Mates, Dana, Neal, David E, Kiemeney, Lambertus A, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Nature Genetics (2013)

Genetics of gene expression and its effect on disease

by Emilsson, Valur, Thorleifsson, Gudmar, Zhang, Bin, Leonardson, Amy S, Zink, Florian, Zhu, Jun, Carlson, Sonia, Helgason, Agnar, Walters, G Bragi, Gunnarsdottir, Steinunn, Mouy, Magali, Steinthorsdottir, Valgerdur, Eiriksdottir, Gudrun H, Bjornsdottir, Gyda, Reynisdottir, Inga, Gudbjartsson, Daniel, Helgadottir, Anna, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Styrkarsdottir, Unnur, Gretarsdottir, Solveig, Magnusson, Kristinn P, Stefansson, Hreinn, Fossdal, Ragnheidur, Kristjansson, Kristleifur, Gislason, Hjortur G, Stefansson, Tryggvi, Leifsson, Bjorn G, Thorsteinsdottir, Unnur, Lamb, John R, Gulcher, Jeffrey R, Reitman, Marc L, Kong, Augustine, Schadt, Eric E, Stefansson, Kari
Published in Nature (2008)

European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene

by Rafnar, Thorunn, Vermeulen, Sita H, Sulem, Patrick, Thorleifsson, Gudmar, Aben, Katja K, Witjes, J Alfred, Grotenhuis, Anne J, Verhaegh, Gerald W, Hulsbergen-van de Kaa, Christina A, Besenbacher, Soren, Gudbjartsson, Daniel, Stacey, Simon N, Gudmundsson, Julius, Johannsdottir, Hrefna, Bjarnason, Hjordis, Zanon, Carlo, Helgadottir, Hafdis, Jonasson, Jon Gunnlaugur, Tryggvadottir, Laufey, Jonsson, Eirikur, Geirsson, Gudmundur, Nikulasson, Sigfus, Petursdottir, Vigdis, Bishop, D Timothy, Chung-Sak, Sei, Choudhury, Ananya, Elliott, Faye, Barrett, Jennifer H, Knowles, Margaret A, de Verdier, Petra J, Ryk, Charlotta, Lindblom, Annika, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, Vineis, Paolo, Polidoro, Silvia, Guarrera, Simonetta, Sacerdote, Carlotta, Panadero, Angeles, Sanz-Velez, José I, Sanchez, Manuel, Valdivia, Gabriel, Garcia-Prats, Maria D, Hengstler, Jan G, Selinski, Silvia, Gerullis, Holger, Ovsiannikov, Daniel, Khezri, Abdolaziz, Aminsharifi, Alireza, Malekzadeh, Mahyar, van den Berg, Leonard H, Ophoff, Roel A, Veldink, Jan H, Zeegers, Maurice P, Kellen, Eliane, Fostinelli, Jacopo, Andreoli, Daniele, Arici, Cecilia, Porru, Stefano, Buntinx, Frank, Ghaderi, Abbas, Golka, Klaus, Mayordomo, José I, Matullo, Giuseppe, Kumar, Rajiv, Steineck, Gunnar, Kiltie, Anne E, Kong, Augustine, Thorsteinsdottir, Unnur, Stefansson, Kari, Kiemeney, Lambertus A
Published in Human Molecular Genetics (2011)

Predicting the probability of death using proteomics

by Eiriksdottir, Thjodbjorg, Ardal, Steinthor, Jonsson, Benedikt A., Lund, Sigrun H., Ivarsdottir, Erna V., Norland, Kristjan, Ferkingstad, Egil, Stefansson, Hreinn, Jónsdóttir, Ingileif, Holm, Hilma, Rafnar, Thorunn, Saemundsdottir, Jona, Norddahl, Gudmundur L., Þorgeirsson, Guðmundur, Gudbjartsson, Daniel F., Sulem, Patrick, Thorsteinsdottir, Unnur, Stefansson, Kari, Úlfarsson, Magnús Örn
Published in Communications Biology (2021)

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma

by Smith, Dirk, Helgason, Hannes, Sulem, Patrick, Bjornsdottir, Unnur Steina, Lim, Ai Ching, Sveinbjornsson, Gardar, Hasegawa, Haruki, Brown, Michael, Ketchem, Randal R, Gavala, Monica, Garrett, Logan, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Magnusson, Olafur T, Eyjolfsson, Gudmundur I, Olafsson, Isleifur, Onundarson, Pall Torfi, Sigurdardottir, Olof, Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn Runar, Ludviksdottir, Dora, Boezen, H Marike, Heinzmann, Andrea, Krueger, Marcus, Porsbjerg, Celeste, Ahluwalia, Tarunveer S, Waage, Johannes, Backer, Vibeke, Deichmann, Klaus A, Koppelman, Gerard H, Bønnelykke, Klaus, Bisgaard, Hans, Masson, Gisli, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Johnston, James A, Jonsdottir, Ingileif, Stefansson, Kari
Published in PLOS Genetics (2017)

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

by Thorleifsson, Gudmar, Walters, G Bragi, Hewitt, Alex W, Masson, Gisli, Helgason, Agnar, DeWan, Andrew, Sigurdsson, Asgeir, Jonasdottir, Adalbjorg, Gudjonsson, Sigurjon A, Magnusson, Kristinn P, Stefansson, Hreinn, Lam, Dennis S C, Tam, Pancy O S, Gudmundsdottir, Gudrun J, Southgate, Laura, Burdon, Kathryn P, Gottfredsdottir, Maria Soffia, Aldred, Micheala A, Mitchell, Paul, St Clair, David, Collier, David, Tang, Nelson, Sveinsson, Orn, Macgregor, Stuart, Martin, Nicholas G, Cree, Angela J, Gibson, Jane, Macleod, Alex, Jacob, Aby, Ennis, Sarah, Young, Terri L, Chan, Juliana C N, Karwatowski, Wojciech S S, Hammond, Christopher J, Thordarson, Kristjan, Zhang, Mingzhi, Wadelius, Claes, Lotery, Andrew J, Trembath, Richard C, Pang, Chi Pui, Hoh, Josephine, Craig, Jamie E, Kong, Augustine, Mackey, David A, Jonasson, Fridbert, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2010)

Sequence variant on 8q24 confers susceptibility to urinary bladder cancer

by Kiemeney, Lambertus A., Thorlacius, Steinunn, Sulem, Patrick, Geller, Frank, Aben, Katja K. H., Stacey, Simon N., Gudmundsson, Julius, Jakobsdottir, Margret, Bergthorsson, Jon T., Sigurdsson, Asgeir, Blondal, Thorarinn, Witjes, J. Alfred, Vermeulen, Sita H., Hulsbergen Van De Kaa, Christina A., Swinkels, Dorine W., Ploeg, Martine, Cornel, Erik B., Vergunst, Henk, Thorgeirsson, Thorgeir E., Gudbjartsson, Daniel, Gudjonsson, Sigurjon A., Thorleifsson, Gudmar, Kristinsson, Kari T., Mouy, Magali, Snorradottir, Steinunn, Placidi, Donatella, Arici, Cecilia, Koppova, Kvetoslava, Gurzau, Eugene, Rudnai, Peter, Kellen, Eliane, Polidoro, Silvia, Guarrera, Simonetta, Sacerdote, Carlotta, Sanchez, Manuel, Saez, Berta, Valdivia, Gabriel, Ryk, Charlotta, De Verdier, Petra, Lindblom, Annika, Golka, Klaus, Bishop, D. Timothy, Knowles, Margaret A., Nikulasson, Sigfus, Petursdottir, Vigdis, Jonsson, Eirikur, Geirsson, Gudmundur, Kristjansson, Baldvin, Mayordomo, Jose I., Steineck, Gunnar, Porru, Stefano, Buntinx, Frank, Zeegers, Maurice P., Fletcher, Tony, Kumar, Rajiv, Matullo, Giuseppe, Vineis, Paolo, Kiltie, Anne E., Gulcher, Jeffrey R., Thorsteinsdottir, Unnur, Kong, Augustine, Rafnar, Thorunn, Stefansson, Kari, CAMPAGNA, MARCELLO
Published in Nature Genetics (2008)

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

by Nioi, Paul, Sigurdsson, Asgeir, Thorleifsson, Gudmar, Helgason, Hannes, Agustsdottir, Arna B, Norddahl, Gudmundur L, Helgadottir, Anna, Magnusdottir, Audur, Jonasdottir, Aslaug, Gretarsdottir, Solveig, Jonsdottir, Ingileif, Steinthorsdottir, Valgerdur, Rafnar, Thorunn, Swinkels, Dorine W, Galesloot, Tessel E, Grarup, Niels, Jørgensen, Torben, Vestergaard, Henrik, Hansen, Torben, Lauritzen, Torsten, Linneberg, Allan, Friedrich, Nele, Krarup, Nikolaj T, Fenger, Mogens, Abildgaard, Ulrik, Hansen, Peter R, Galløe, Anders M, Braund, Peter S, Nelson, Christopher P, Hall, Alistair S, Williams, Michael J A, van Rij, Andre M, Jones, Gregory T, Patel, Riyaz S, Levey, Allan I, Hayek, Salim, Shah, Svati H, Reilly, Muredach, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Kiemeney, Lambertus A, Quyyumi, Arshed A, Rader, Daniel J, Kraus, William E, Samani, Nilesh J, Pedersen, Oluf, Thorgeirsson, Gudmundur, Masson, Gisli, Holm, Hilma, Gudbjartsson, Daniel, Sulem, Patrick, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in New England Journal of Medicine (2016)

Variant ASGR1 associated with a reduced risk of coronary artery disease

by Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, Anna, Magnusdottir, A., Jonasdottir, A., Grétarsdóttir, Sólveig, Jonsdottir, I, Steinthorsdottir, V., Rafnar, Thorunn, Swinkels, D. W., Galesloot, T. E., Grarup, N., Jørgensen, T, Vestergaard, H., Hansen, Torben, Lauritzen, T, Linneberg, A., Friedrich, Nele, Krarup, N T, Fenger, Mogens, Abildgaard, U., Hansen, Peter R, Galløe, Anders M., Braund, P. S., Nelson, Christopher P, Hall, Alistair S, Williams, Michael J A, van Rij, Andre M, Jones, Gregory T, Patel, Sanjay R, Levey, Allan I, Hayek, S., Shah, Svati H, Reilly, Marie, Eyjolfsson, G. I., Sigurdardottir, O., Olafsson, Isleifur, Kiemeney, L. A., Quyyumi, Arshed A, Rader, Daniel J, Kraus, W. E., Samani, Nilesh J, Pedersen, O., Thorgeirsson, G., Masson, G., Holm, Hilma, Gudbjartsson, D. F., Sulem, P., Thorsteinsdottir, Unnur, Stefansson, K
Published in New England Journal of Medicine (2016)