Search Results - Open Polar - "secretase"

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1

A study of b-secretase cleaved Alzheimer amyloid precursor protein

by Sennvik, Kristina
Published 2002
“... by proteases P- and gamma-secretase. Alternatively, APP may be cleaved within the A-beta region by alpha...”

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Doctoral or Postdoctoral Thesis
Select result number 2
2

Characterization of the novel “Uppsala mutation” causing a familial form of early onset Alzheimer’s disease

by Pagnon de la Vega, María
Published 2021
“... precursor protein (APP) by β-secretase and γ-secretase, while α-secretase prevents Aβ generation. According...”

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Doctoral or Postdoctoral Thesis
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3

Pathogenic Mechanisms of the Arctic Alzheimer Mutation

by Sahlin, Charlotte
Published 2007
“... addressing if and how the mutation affects APP processing. Evidence of a shift towards β-secretase cleavage...”

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Doctoral or Postdoctoral Thesis
Select result number 4
4

Distribution and pathophysiological role of amyloid precursor protein and presenilin 1 : characterization in rats and in vitro studies on the pathogenic arctic mutation

by Nilsberth, Camilla
Published 2002
“...) by the proteases beta- and gamma-secretase. A familial link can be found in approximately half of all Alzheimer...”

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Doctoral or Postdoctoral Thesis