Search Results

An isogenic panel of App knock-in mouse models: Profiling β-secretase inhibition and endosomal abnormalities

by Watamura, Naoto, Sato, Kaori, Shiihashi, Gen, Iwasaki, Ayami, Kamano, Naoko, Takahashi, Mika, Sekiguchi, Misaki, Mihira, Naomi, Fujioka, Ryo, Nagata, Kenichi, Hashimoto, Shoko, Saito, Takashi, Ohshima, Toshio, Saido, Takaomi C., Sasaguri, Hiroki
Published in Science Advances (2022)

The Arctic Alzheimer mutation favors intracellular amyloid‐β production by making amyloid precursor protein less available to α‐secretase

by Sahlin, Charlotte, Lord, Anna, Magnusson, Kristina, Englund, Hillevi, Almeida, Claudia G., Greengard, Paul, Nyberg, Fred, Gouras, Gunnar K., Lannfelt, Lars, Nilsson, Lars N.G.
Published in Journal of Neurochemistry (2007)

Neuroactive venom compounds obtained from Phlogiellus bundokalbo as potential leads for neurodegenerative diseases: insights on their acetylcholinesterase and beta-secretase inhibitory activities in vitro

by Simon Miguel M. Lopez, Jeremey S. Aguilar, Jerene Bashia B. Fernandez, Angelic Gayle J. Lao, Mitzi Rain R. Estrella, Mark Kevin P. Devanadera, Cydee Marie V. Ramones, Aaron Joseph L. Villaraza, Leonardo A. Guevarra Jr., Myla R. Santiago-Bautista, Librado A. Santiago
Published in Journal of Venomous Animals and Toxins including Tropical Diseases (2021)

P4–041: The Arctic Alzheimer mutation favors Aβ production by making APP less available to α–secretase at the cell surface

by Stenh, Charlotte, Lord, Anna, Magnusson, Kristina, Englund, Hillevi, Almeida, Claudia G., Greengard, Paul, Nyberg, Fred, Gouras, Gunnar K., Lannfelt, Lars, Nilsson, Lars N.G.
Published in Alzheimer's & Dementia (2006)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

by Schilling, Sandra, Pradhan, Ajay, Heesch, Amelie, Helbig, Andrea, Blennow, Kaj, Koch, Christian, Bertgen, Lea, Koo, Edward H., Brinkmalm, Gunnar, Zetterberg, Henrik, Eggert, Simone
Published in Acta Neuropathologica Communications (2023)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

by Schilling, S, Pradhan, A, Heesch, A, Helbig, A, Blennow, K, Koch, C, Bertgen, L, Koo, EH, Brinkmalm, G, Zetterberg, H, Kins, S, Eggert, S
Published 2023

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

by Sandra Schilling, Ajay Pradhan, Amelie Heesch, Andrea Helbig, Kaj Blennow, Christian Koch, Lea Bertgen, Edward H. Koo, Gunnar Brinkmalm, Henrik Zetterberg, Stefan Kins, Simone Eggert
Published in Acta Neuropathologica Communications (2023)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

by Schilling, S., Pradhan, A., Heesch, A., Helbig, A., Blennow, K., Koch, C., Bertgen, L., Koo, E., Brinkmalm, G., Zetterberg, H., Kins, S., Eggert, S.
Published in Acta Neuropathologica Communications (2023)

Regulation of osteoprotegerin expression by Notch signaling in human oral squamous cell carcinoma cell line

by Jeeranan Manokawinchoke, Thanaphum Osathanon, Prasit Pavasant
Published in Asian Pacific Journal of Tropical Biomedicine (2016)

The Arctic Alzheimer mutation enhances sensitivity to toxic stress in human neuroblastoma cells

by Sennvik, Kristina, Nilsberth, Camilla, Stenh, Charlotte, Lannfelt, Lars, Benedikz, Eirikur
Published 2002

Point mutations in Aβ result in the formation of distinct polymorphic aggregates in the presence of lipid bilayers.

by Phillip M Pifer, Elizabeth A Yates, Justin Legleiter
Published in PLoS ONE (2011)