Search Results

The C99 domain of the amyloid precursor protein resides in the disordered membrane phase

by Capone, Ricardo, Tiwari, Ajit, Hadziselimovic, Arina, Peskova, Yelena, Hutchison, James M., Sanders, Charles R., Kenworthy, Anne K.
Published in Journal of Biological Chemistry (2021)

Caspase-6 Activation in Familial Alzheimer Disease Brains Carrying Amyloid Precursor Protein, Presenilin I or Presenilin II Mutations

by Albrecht, Steffen, Bogdanovic, Nenad, Ghetti, Bernardino, Winblad, Bengt, LeBlanc, Andréa C.
Published in Journal of Neuropathology & Experimental Neurology (2009)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein...

by Schilling, Sandra, Pradhan, Ajay, Heesch, Amelie, Helbig, Andrea, Blennow, Kaj, Koch, Christian, Bertgen, Lea, Koo, Edward H., Brinkmalm, Gunnar, Zetterberg, Henrik, Kins, Stefan, Eggert, Simone
Published in Acta Neuropathologica Communications (2023)

Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced Behavioral...

by Holden, Sarah, Kundu, Payel, Torres, Eileen R. S., Sudhakar, Reetesh, Krenik, Destine, Grygoryev, Dmytro, Turker, Mitchel S., Raber, Jacob
Published in Frontiers in Aging Neuroscience (2022)

Aβ Oligomer-Mediated Long-Term Potentiation Impairment Involves Protein Phosphatase 1-Dependent Mechanisms

by Knobloch, Marlen, Farinelli, Mélissa, Konietzko, Uwe, Nitsch, Roger M., Mansuy, Isabelle M.
Published in Journal of Neuroscience (2007)

Dutch and arctic mutant peptides of β amyloid1–40 differentially affect the FGF-2 pathway in brain endothelium

by Solito, Raffaella, Corti, Federico, Fossati, Silvia, Mezhericher, Emiliya, Donnini, Sandra, Ghiso, Jorge, Giachetti, Antonio, Rostagno, Agueda, Ziche, Marina
Published in Experimental Cell Research (2008)

Pulsed hydrogen deuterium exchange reveals altered structures and mechanisms in the aggregation of familial Alzheimer’s disease mutants

by Illes-Toth, Eva, Meisl, Georg, Rempel, Don L., Knowles, Tuomas P. J., Gross, Michael L.
Published in ACS Chemical Neuroscience (2021)

Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

by Merlini, Mario, Meyer, Eric P., Ulmann-Schuler, Alexandra, Nitsch, Roger M.
Published in Acta Neuropathologica (2011)

β-Amyloid Monomers Are Neuroprotective

by Giuffrida, Maria Laura, Caraci, Filippo, Pignataro, Bruno, Cataldo, Sebastiano, De Bona, Paolo, Bruno, Valeria, Molinaro, Gemma, Pappalardo, Giuseppe, Messina, Angela, Palmigiano, Angelo, Garozzo, Domenico, Nicoletti, Ferdinando, Rizzarelli, Enrico, Copani, Agata
Published in Journal of Neuroscience (2009)

The Arctic/Swedish APP mutation alters the impact of chronic stress on cognition in mice

by Cortese, Aurelio, Delgado‐Morales, Raul, Almeida, Osborne F. X., Romberg, Carola
Published in European Journal of Neuroscience (2019)

Recent Advances in the Modeling of Alzheimer’s Disease

by Sasaguri, Hiroki, Hashimoto, Shoko, Watamura, Naoto, Sato, Kaori, Takamura, Risa, Nagata, Kenichi, Tsubuki, Satoshi, Ohshima, Toshio, Yoshiki, Atsushi, Sato, Kenya, Kumita, Wakako, Sasaki, Erika, Kitazume, Shinobu, Nilsson, Per, Winblad, Bengt, Saito, Takashi, Iwata, Nobuhisa, Saido, Takaomi C.
Published in Frontiers in Neuroscience (2022)

Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vi...

by Tackenberg, Christian, Kulic, Luka, Nitsch, Roger M.
Published in PLOS ONE (2020)

Fecal Implants From App(NL–G–F) and App(NL–G–F/E4) Donor Mice Sufficient to Induce Behavioral Phenotypes in Germ-Free Mice

by Kundu, Payel, Stagaman, Keaton, Kasschau, Kristin, Holden, Sarah, Shulzhenko, Natalia, Sharpton, Thomas J., Raber, Jacob
Published in Frontiers in Behavioral Neuroscience (2022)

Integrated analysis of behavioral, epigenetic, and gut microbiome analyses in App(NL-G-F), App(NL-F), and wild type mice

by Kundu, Payel, Torres, Eileen Ruth S., Stagaman, Keaton, Kasschau, Kristin, Okhovat, Mariam, Holden, Sarah, Ward, Samantha, Nevonen, Kimberly A., Davis, Brett A., Saito, Takashi, Saido, Takaomi C., Carbone, Lucia, Sharpton, Thomas J., Raber, Jacob
Published in Scientific Reports (2021)

Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains

by Yang, Yang, Zhang, Wenjuan, Murzin, Alexey G., Schweighauser, Manuel, Huang, Melissa, Lövestam, Sofia, Peak-Chew, Sew Y., Saito, Takashi, Saido, Takaomi C., Macdonald, Jennifer, Lavenir, Isabelle, Ghetti, Bernardino, Graff, Caroline, Kumar, Amit, Nordberg, Agneta, Goedert, Michel, Scheres, Sjors H. W.
Published in Acta Neuropathologica (2023)