Search Results - Open Polar - "directed evolution"

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Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution

by Cen, Yixin, Singh, Warispreet, Arkin, Mamatjan, Moody, Thomas S., Huang, Meilan, Zhou, Jiahai, Wu, Qi, Reetz, Manfred T.
Published in Nature Communications (2019)
“..., provided additional mutations are introduced by directed evolution. By employing Candida antarctica lipase...”

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Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters

by Xu, Jian, Cen, Yixin, Singh, Warispreet, Fan, Jiajie, Wu, Lian, Lin, Xianfu, Zhou, Jiahai, Huang, Meilan, Reetz, Manfred T., Wu, Qi
Published in Journal of the American Chemical Society (2019)
“... significant success has been achieved in directed evolution of enzymes in general, stereodivergent engineering...”

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