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Acute Mountain Sickness Symptom Severity at the South Pole: The Influence of Self-Selected Prophylaxis with Acetazolamide.

by Michael F Harrison, Paul J Anderson, Jacob B Johnson, Maile Richert, Andrew D Miller, Bruce D Johnson
Published in PLOS ONE (2016)
“...INTRODUCTION:Acetazolamide, a carbonic anhydrase inhibitor, remains the only FDA approved...”

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2

Incidence and Symptoms of High Altitude Illness in South Pole Workers: Antarctic Study of Altitude Physiology (ASAP)

by Paul J. Anderson, Andrew D. Miller, Kathy A. O'malley, Maile L. Ceridon, Kenneth C. Beck, Christina M. Wood, Heather J. Wiste, Joshua J. Mueller, Jacob B. Johnson, Bruce D. Johnson
Published in Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine (2011)
“... and the field effectiveness of acetazolamide in a highly controlled setting. We hypothesized...”

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3

Carbonic anhydrase is involved in calcification by the benthic foraminifer Amphistegina lessonii

by S. de Goeyse, A. E. Webb, G.-J. Reichart, L. J. de Nooijer
Published in Biogeosciences (2021)
“... that inhibition of carbonic anhydrase by acetazolamide (AZ) stopped most of the calcification process. Inhibition...”

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4

Cloning, purification, kinetic and anion inhibition studies of a recombinant β-carbonic anhydrase from the Atlantic salmon parasite platyhelminth Gyrodactylus salaris

by Ashok Aspatwar, Harlan Barker, Heidi Aisala, Ksenia Zueva, Marianne Kuuslahti, Martti Tolvanen, Craig R. Primmer, Jaakko Lumme, Alessandro Bonardi, Amit Tripathi, Seppo Parkkila, Claudiu T. Supuran
Published in Journal of Enzyme Inhibition and Medicinal Chemistry (2022)
“... kcat/Km of 7.58 × 106 M−1 × s−1. This activity was inhibited by acetazolamide (KI of 0.46 µM), a...”

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5

Carbonic anhydrase activity of integral-functional complexes of thylakoid membranes of spinach chloroplasts

by A. V. Semenihin, O. K. Zolotareva
Published in The Ukrainian Biochemical Journal (2015)
“.... The water-soluble acetazolamide, an inhibitor of CA, unlike lipophilic ethoxyzolamide inhibited CA activity...”

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6

Light Levels Affect Carbon Utilisation in Tropical Seagrass under Ocean Acidification.

by Yan X Ow, Sven Uthicke, Catherine J Collier
Published in PLOS ONE (2016)
“... inhibitor, acetazolamide) and TRIS buffer (pH 8.0). We observed a strong dependence on energy driven H+-HCO3...”

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7

Mitochondrial PCK2 Missense Variant in Shetland Sheepdogs with Paroxysmal Exercise-Induced Dyskinesia (PED)

by Jasmin Nessler, Petra Hug, Paul J. J. Mandigers, Peter A. J. Leegwater, Vidhya Jagannathan, Anibh M. Das, Marco Rosati, Kaspar Matiasek, Adrian C. Sewell, Marion Kornberg, Marina Hoffmann, Petra Wolf, Andrea Fischer, Andrea Tipold, Tosso Leeb
Published in Genes (2020)
“... in three dogs or a tryptophan-rich, gluten-free, seafood-based diet, stress-reduction, and acetazolamide...”

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