Search Results

Genomic evidence for the Pleistocene and recent population history of Native Americans

by Raghavan, Maanasa, Steinrücken, Matthias, Harris, Kelley, Schiffels, Stephan, Rasmussen, Simon, DeGiorgio, Michael, Albrechtsen, Anders, Valdiosera, Cristina, Ávila-Arcos, María C., Malaspinas, Anna Sapfo, Eriksson, Anders, Moltke, Ida, Metspalu, Mait, Homburger, Julian R., Wall, Jeff, Cornejo, Omar E., Moreno-Mayar, J. Víctor, Korneliussen, Thorfinn S., Pierre, Tracey, Rasmussen, Morten, Campos, Paula F., De Barros Damgaard, Peter, Allentoft, Morten E., Lindo, John, Metspalu, Ene, Rodríguez-Varela, Ricardo, Mansilla, Josefina, Henrickson, Celeste, Seguin-Orlando, Andaine, Malmstöm, Helena, Stafford, Thomas, Shringarpure, Suyash S., Moreno-Estrada, Andrés, Karmin, Monika, Tambets, Kristiina, Bergström, Anders, Xue, Yali, Warmuth, Vera, Friend, Andrew D., Singarayer, Joy, Valdes, Paul, Balloux, Francois, Leboreiro, Ilán, Vera, Jose Luis, Rangel-Villalobos, Hector, Pettener, Davide, Luiselli, Donata, Davis, Loren G., Heyer, Evelyne, Zollikofer, Christoph P E, Ponce De León, Marcia S., Smith, Colin I., Grimes, Vaughan, Pike, Kelly Anne, Deal, Michael, Fuller, Benjamin T., Arriaza, Bernardo, Standen, Vivien, Luz, Maria F., Ricaut, Francois, Guidon, Niede, Osipova, Ludmila, Voevoda, Mikhail I., Posukh, Olga L., Balanovsky, Oleg, Lavryashina, Maria, Bogunov, Yuri, Khusnutdinova, Elza, Gubina, Marina, Balanovska, Elena, Fedorova, Sardana, Litvinov, Sergey, Malyarchuk, Boris, Derenko, Miroslava, Mosher, M. J., Archer, David, Cybulski, Jerome, Petzelt, Barbara, Mitchell, Joycelynn, Worl, Rosita, Norman, Paul J., Parham, Peter, Kemp, Brian M., Kivisild, Toomas, Tyler-Smith, Chris, Sandhu, Manjinder S., Crawford, Michael, Villems, Richard, Smith, David Glenn, Waters, Michael R., Goebel, Ted, Johnson, John R., Malhi, Ripan S., Jakobsson, Mattias, Meltzer, David J., Manica, Andrea, Durbin, Richard, Bustamante, Carlos D., Song, Yun S., Nielsen, Rasmus, Willerslev, Eske
Published in Science (2015)

Genomic evidence for the Pleistocene and recent population history of Native Americans

by Raghavan, Maanasa, Steinrücken, Matthias, Harris, Kelley, Schiffels, Stephan, Rasmussen, Simon, DeGiorgio, Michael, Albrechtsen, Anders, Valdiosera Morales, Cristina E., Avila Arcos, Maria del Carmen, Malaspinas, Anna Sapfo, Eriksson, Anders, Moltke, Ida, Metspalu, Mait, Homburger, Julian R, Wall, Jeff, Cornejo, Omar E, Moreno Mayar, José Victor, Korneliussen, Thorfinn Sand, Pierre, Tracey Lynn, Rasmussen, Morten, Campos, Paula, Damgaard, Peter de Barros, Allentoft, Morten Erik, Lindo, John, Metspalu, Ene, Rodríguez-Varela, Ricardo, Mansilla, Josefina, Henrickson, Celeste, Seguin-Orlando, Andaine, Malmström, Helena, Stafford jr., Thomas, Shringarpure, Suyash S, Moreno-Estrada, Andrés, Karmin, Monika, Tambets, Kristiina, Bergström, Anders, Xue, Yali, Warmuth, Vera, Friend, Andrew D, Singarayer, Joy, Valdes, Paul, Balloux, Francois, Leboreiro, Ilán, Vera, Jose Luis, Rangel-Villalobos, Hector, Pettener, Davide, Luiselli, Donata, Davis, Loren G, Heyer, Evelyne, Zollikofer, Christoph P E, Ponce de León, Marcia S, Smith, Colin I, Grimes, Vaughan, Pike, Kelly-Anne, Deal, Michael, Fuller, Benjamin T, Arriaza, Bernardo, Standen, Vivien, Luz, Maria F, Ricaut, Francois, Guidon, Niede, Osipova, Ludmila, Voevoda, Mikhail I, Posukh, Olga L, Balanovsky, Oleg, Lavryashina, Maria, Bogunov, Yuri, Khusnutdinova, Elza, Gubina, Marina, Balanovska, Elena, Fedorova, Sardana, Litvinov, Sergey, Malyarchuk, Boris, Derenko, Miroslava, Mosher, M J, Archer, David, Cybulski, Jerome, Petzelt, Barbara, Mitchell, Joycelynn, Worl, Rosita, Norman, Paul J, Parham, Peter, Kemp, Brian M, Kivisild, Toomas, Tyler-Smith, Chris, Sandhu, Manjinder S, Crawford, Michael, Villems, Richard, Smith, David Glenn, Waters, Michael R, Goebel, Ted, Johnson, John R, Malhi, Ripan S, Jakobsson, Mattias, Meltzer, David J., Manica, Andrea, Durbin, Richard, Bustamante, Carlos D, Song, Yun S, Nielsen, Rasmus, Willerslev, Eske
Published in Science (2015)

The genetic prehistory of the New World Arctic

by Raghavan, Maanasa, DeGiorgio, Michael, Albrechtsen, Anders, Moltke, Ida, Skoglund, Pontus, Korneliussen, Thorfinn S., Grønnow, Bjarne, Appelt, Martin, Gulløv, Hans Christian, Friesen, T. Max, Fitzhugh, William, Malmström, Helena, Rasmussen, Simon, Olsen, Jesper, Melchior, Linea, Fuller, Benjamin T., Fahrni, Simon M., Stafford, Thomas, Grimes, Vaughan, Renouf, M. A Priscilla, Cybulski, Jerome, Lynnerup, Niels, Lahr, Marta Mirazon, Britton, Kate, Knecht, Rick, Arneborg, Jette, Metspalu, Mait, Cornejo, Omar E., Malaspinas, Anna Sapfo, Wang, Yong, Rasmussen, Morten, Raghavan, Vibha, Hansen, Thomas V O, Khusnutdinova, Elza, Pierre, Tracey, Dneprovsky, Kirill, Andreasen, Claus, Lange, Hans, Hayes, M. Geoffrey, Coltrain, Joan, Spitsyn, Victor A., Götherström, Anders, Orlando, Ludovic, Kivisild, Toomas, Villems, Richard, Crawford, Michael H., Nielsen, Finn C., Dissing, Jørgen, Heinemeier, Jan, Meldgaard, Morten, Bustamante, Carlos, O'Rourke, Dennis H., Jakobsson, Mattias, Gilbert, M. Thomas P, Nielsen, Rasmus, Willerslev, Eske
Published in Science (2014)

The genetic prehistory of the New World Arctic

by Raghavan, Maanasa, DeGiorgio, Michael, Albrechtsen, Anders, Moltke, Ida, Skoglund, Pontus, Korneliussen, Thorfinn Sand, Grønnow, Bjarne, Appelt, Martin, Gulløv, Hans Christian, Friesen, T Max, Fitzhugh, William, Malmström, Helena Susanne, Rasmussen, Simon, Olsen, Jesper, Melchior, Linea Cecilie, Fuller, Benjamin T, Fahrni, Simon M, Stafford jr., Thomas, Grimes, Vaughan, Renouf, M A Priscilla, Cybulski, Jerome, Lynnerup, Niels, Lahr, Marta Mirazon, Britton, Kate, Knecht, Rick, Arneborg, Jette, Metspalu, Mait, Cornejo, Omar E, Malaspinas, Anna Sapfo, Wang, Yong, Rasmussen, Morten, Raghavan, Vibha, Hansen, Thomas van Overeem, Khusnutdinova, Elza, Pierre, Tracey Lynn, Dneprovsky, Kirill, Andreasen, Claus, Lange, Hans, Hayes, M Geoffrey, Coltrain, Joan, Spitsyn, Victor A, Götherström, Anders, Orlando, Ludovic Antoine Alexandre, Kivisild, Toomas, Villems, Richard, Crawford, Michael H, Nielsen, Finn Cilius, Dissing, Jørgen, Heinemeier, Jan, Meldgaard, Morten, Bustamante, Carlos, O'Rourke, Dennis H, Jakobsson, Mattias, Gilbert, M Thomas P, Nielsen, Rasmus, Willerslev, Eske
Published in Science (2014)

The genetic prehistory of the New World Arctic

by Raghavan, Maanasa, DeGiorgio, Michael, Albrechtsen, Anders, Moltke, Ida, Skoglund, Pontus, Korneliussen, Thorfinn S., Grønnow, Bjarne, Appelt, Martin, Gulløv, Hans Christian, Friesen, T. Max, Fitzhugh, William, Malmström, Helena, Rasmussen, Simon, Olsen, Jesper, Melchior, Linea, Fuller, Benjamin T., Fahrni, Simon M., Stafford, Thomas, Grimes, Vaughan, Renouf, M. A. Priscilla, Cybulski, Jerome, Lynnerup, Niels, Lahr, Marta Mirazon, Britton, Kate, Knecht, Rick, Arneborg, Jette, Metspalu, Mait, Cornejo, Omar E., Malaspinas, Anna-Sapfo, Wang, Yong, Rasmussen, Morten, Raghavan, Vibha, Hansen, Thomas V. O., Khusnutdinova, Elza, Pierre, Tracey, Dneprovsky, Kirill, Andreasen, Claus, Lange, Hans, Hayes, M. Geoffrey, Coltrain, Joan, Spitsyn, Victor A., Gotherstrom, Anders, Orlando, Ludovic, Kivisild, Toomas, Villems, Richard, Crawford, Michael H., Nielsen, Finn C., Dissing, Jørgen, Heinemeier, Jan, Meldgaard, Morten, Bustamante, Carlos, O'Rourke, Dennis H., Jakobsson, Mattias, Gilbert, M. Thomas P., Nielsen, Rasmus, Willerslev, Eske
Published in Science (2014)

Genetic Loss of Sucrase-Isomaltase Function:Mechanisms, Implications, and Future Perspectives

by Senftleber, Ninna Karsbæk, Ramne, Stina, Moltke, Ida, Jørgensen, Marit Eika, Albrechtsen, Anders, Hansen, Torben, Andersen, Mette K.
Published in The Application of Clinical Genetics (2023)

Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts

by Andersen, Mette K., Skotte, Line, Jørsboe, Emil, Polito, Ryan, Stæger, Frederik F., Aldiss, Peter, Hanghøj, Kristian, Waples, Ryan K., Santander, Cindy G., Grarup, Niels, Dahl-Petersen, Inger K., Diaz, Lars J., Overvad, Maria, Senftleber, Ninna K., Søborg, Bolette, Larsen, Christina V. L., Lemoine, Clara, Pedersen, Oluf, Feenstra, Bjarke, Bjerregaard, Peter, Melbye, Mads, Jørgensen, Marit E., Færgeman, Nils J., Koch, Anders, Moritz, Thomas, Gillum, Matthew P., Moltke, Ida, Hansen, Torben, Albrechtsen, Anders
Published in Gastroenterology (2022)

Origin and expansion of the world’s most widespread pinniped:Range-wide population genomics of the harbour seal ( Phoca vitulina )

by Liu, Xiaodong, Schjøtt, Suzanne Rønhøj, Granquist, Sandra M., Rosing-Asvid, Aqqalu, Dietz, Rune, Teilmann, Jonas, Galatius, Anders, Cammen, Kristina, O’Corry-Crowe, Greg, Harding, Karin, Härkönen, Tero, Hall, Ailsa, Carroll, Emma L., Kobayashi, Yumi, Hammill, Mike, Stenson, Garry, Kirstine Frie, Anne, Lydersen, Christian, Kovacs, Kit M., Andersen, Liselotte W., Hoffman, Joseph I., Goodman, Simon J., Vieira, Filipe G., Heller, Rasmus, Moltke, Ida, Tange Olsen, Morten
Published in Molecular Ecology (2022)

A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland

by Thuesen, Anne Cathrine Baun, Stæger, Frederik Filip, Kaci, Alba, Solheim, Marie Holm, Aukrust, Ingvild, Jørsboe, Emil, Santander, Cindy G., Andersen, Mette K., Li, Zilong, Gilly, Arthur, Stinson, Sara Elizabeth, Gjesing, Anette Prior, Bjerregaard, Peter, Pedersen, Michael Lynge, Larsen, Christina Viskum Lytken, Grarup, Niels, Jørgensen, Marit E., Zeggini, Eleftheria, Bjørkhaug, Lise, Njølstad, Pål Rasmus, Albrechtsen, Anders, Moltke, Ida, Hansen, Torben
Published in The Lancet Regional Health - Europe (2023)

The genetic history of Greenlandic-European contact

by Waples, Ryan K., Hauptmann, Aviaja L., Seiding, Inge Høst, Jørsboe, Emil, Jørgensen, Marit E., Grarup, Niels, Andersen, Mette K., Larsen, Christina V. L., Bjerregaard, Peter, Hellenthal, Garrett, Hansen, Torben, Albrechtsen, Anders, Moltke, Ida
Published in Current Biology (2021)

GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal

by Senftleber, Ninna Karsbæk, Andersen, Mette K., Jørsboe, Emil, Stæger, Frederik Filip, Nøhr, Anne Krogh, Garcia-Erill, Genis, Meisner, Jonas, Santander, Cindy G., Balboa, Renzo F., Gilly, Arthur, Bjerregaard, Peter, Larsen, Christina Viskum Lytken, Grarup, Niels, Jørgensen, Marit Eika, Zeggini, Eleftheria, Moltke, Ida, Hansen, Torben, Albrechtsen, Anders
Published in European Journal of Human Genetics (2024)

Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

by Grarup, Niels, Moltke, Ida, Andersen, Mette K., Bjerregaard, Peter, Larsen, Christina V.L., Dahl-Petersen, Inger K., Jørsboe, Emil, Tiwari, Hemant K., Hopkins, Scarlett E., Wiener, Howard W., Boyer, Bert B., Linneberg, Allan, Pedersen, Oluf, Jørgensen, Marit E., Albrechtsen, Anders, Hansen, Torben
Published in Diabetologia (2018)

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

by Grarup, Niels, Moltke, Ida, Andersen, Mette K, Dalby, Maria, Vitting-Seerup, Kristoffer, Kern, Timo, Mahendran, Yuvaraj, Jørsboe, Emil, Larsen, Christina V L, Dahl-Petersen, Inger K, Gilly, Arthur, Suveges, Daniel, Dedoussis, George, Zeggini, Eleftheria, Pedersen, Oluf, Andersson, Robin, Bjerregaard, Peter, Jørgensen, Marit E, Albrechtsen, Anders, Hansen, Torben
Published in Nature Genetics (2018)

Population genomics of the muskox' resilience in the near absence of genetic variation

by Pečnerová, Patrícia, Lord, Edana, Garcia-Erill, Genís, Hanghøj, Kristian, Rasmussen, Malthe Sebro, Meisner, Jonas, Liu, Xiaodong, van der Valk, Tom, Santander, Cindy G., Quinn, Liam, Lin, Long, Liu, Shanlin, Carøe, Christian, Dalerum, Fredrik, Götherström, Anders, Måsviken, Johannes, Vartanyan, Sergey, Raundrup, Katrine, Al-Chaer, Amal, Rasmussen, Linett, Hvilsom, Christina, Heide-Jørgensen, Mads Peter, Sinding, Mikkel Holger S., Aastrup, Peter, Van Coeverden de Groot, Peter J., Schmidt, Niels Martin, Albrechtsen, Anders, Dalén, Love, Heller, Rasmus, Moltke, Ida, Siegismund, Hans Redlef
Published in Molecular Ecology (2024)

An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention

by Jørsboe, Emil, Andersen, Mette K., Skotte, Line, Stæger, Frederik F., Færgeman, Nils J., Hanghøj, Kristian, Santander, Cindy G., Senftleber, Ninna K., Diaz, Lars J., Overvad, Maria, Waples, Ryan K., Geller, Frank, Bjerregaard, Peter, Melbye, Mads, Larsen, Christina V.L., Feenstra, Bjarke, Anders Koch, Koch, Jørgensen, Marit E., Grarup, Niels, Moltke, Ida, Albrechtsen, Anders, Hansen, Torben
Published in Human Genetics and Genomics Advances (2022)

The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation:Insights from the Greenlandic Inuit

by Pedersen, Casper-Emil T, Lohmueller, Kirk E, Grarup, Niels, Bjerregaard, Peter, Hansen, Torben, Siegismund, Hans R, Moltke, Ida, Albrechtsen, Anders
Published in Genetics (2017)

Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population

by Appel, Emil V.R., Moltke, Ida, Jørgensen, Marit E., Bjerregaard, Peter, Linneberg, Allan, Pedersen, Oluf, Albrechtsen, Anders, Hansen, Torben, Grarup, Niels
Published in European Journal of Human Genetics (2018)

GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal

by Senftleber, Ninna Karsbæk, Andersen, Mette K., Jørsboe, Emil, Stæger, Frederik Filip, Nøhr, Anne Krogh, Garcia-Erill, Genis, Meisner, Jonas, Santander, Cindy G., Balboa, Renzo F., Gilly, Arthur, Bjerregaard, Peter, Larsen, Christina Viskum Lytken, Grarup, Niels, Jørgensen, Marit Eika, Zeggini, Eleftheria, Moltke, Ida, Hansen, Torben, Albrechtsen, Anders
Published in European Journal of Human Genetics (2024)

Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans

by Lin, Long, Andersen, Mette K., Stæger, Frederik Filip, Li, Zilong, Hanghøj, Kristian, Linneberg, Allan, Grarup, Niels, Jørgensen, Marit Eika, Hansen, Torben, Moltke, Ida, Albrechtsen, Anders
Published in Genome Medicine (2024)

Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders

by Andersen, Mette Korre, Jørsboe, Emil, Sandholt, Camilla Helene, Grarup, Niels, Jørgensen, Marit Eika, Færgeman, Nils Joakim, Bjerregaard, Peter, Pedersen, Oluf, Moltke, Ida, Hansen, Torben, Albrechtsen, Anders
Published in PLOS Genetics (2016)