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Assessing the effect of insecticide-treated cattle on tsetse abundance and trypanosome transmission at the wildlife-livestock interface in Serengeti, Tanzania.

by Jennifer S Lord, Rachel S Lea, Fiona K Allan, Mechtilda Byamungu, David R Hall, Jessica Lingley, Furaha Mramba, Edith Paxton, Glyn A Vale, John W Hargrove, Liam J Morrison, Stephen J Torr, Harriet K Auty
Published in PLOS Neglected Tropical Diseases (2020)
“... use by farmers, tsetse abundance and trypanosome prevalence, with mathematical models, to quantify...”

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2

Using detergent to enhance detection sensitivity of African trypanosomes in human CSF and blood by loop-mediated isothermal amplification (LAMP).

by Dennis J Grab, Olga V Nikolskaia, Noboru Inoue, Oriel M M Thekisoe, Liam J Morrison, Wendy Gibson, J Stephen Dumler
Published in PLoS Neglected Tropical Diseases (2011)
“... for the detection of a broad range of pathogenic microorganisms including African trypanosomes. While many LAMP...”

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3

A major genetic locus in Trypanosoma brucei is a determinant of host pathology.

by Liam J Morrison, Andy Tait, Sarah McLellan, Lindsay Sweeney, C Michael R Turner, Annette MacLeod
Published in PLoS Neglected Tropical Diseases (2009)
“... on disease pathology during infections with trypanosomes has been well studied in recent years, but the role...”

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4

Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole.

by Pieter C Steketee, Federica Giordani, Isabel M Vincent, Kathryn Crouch, Fiona Achcar, Nicholas J Dickens, Liam J Morrison, Annette MacLeod, Michael P Barrett
Published in PLOS Neglected Tropical Diseases (2021)
“.... However, less is known about the potential mechanisms leading to acoziborole resistance in trypanosomes...”

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5

Population genetics of Trypanosoma brucei rhodesiense: clonality and diversity within and between foci.

by Craig W Duffy, Lorna MacLean, Lindsay Sweeney, Anneli Cooper, C Michael R Turner, Andy Tait, Jeremy Sternberg, Liam J Morrison, Annette MacLeod
Published in PLoS Neglected Tropical Diseases (2013)
“...African trypanosomes are unusual among pathogenic protozoa in that they can undergo their complete...”

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6

Application of long read sequencing to determine expressed antigen diversity in Trypanosoma brucei infections.

by Siddharth Jayaraman, Claire Harris, Edith Paxton, Anne-Marie Donachie, Heli Vaikkinen, Richard McCulloch, James P J Hall, John Kenny, Luca Lenzi, Christiane Hertz-Fowler, Christina Cobbold, Richard Reeve, Tom Michoel, Liam J Morrison
Published in PLOS Neglected Tropical Diseases (2019)
“..., and provides novel insights into the complexity and nature of VSG expression in trypanosomes, revealing...”

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7

Parasite specific 7SL-derived small RNA is an effective target for diagnosis of active trypanosomiasis infection.

by Stephen M Chiweshe, Pieter C Steketee, Siddharth Jayaraman, Edith Paxton, Kyriaki Neophytou, Heidi Erasmus, Michel Labuschagne, Anneli Cooper, Annette MacLeod, Finn E Grey, Liam J Morrison
Published in PLOS Neglected Tropical Diseases (2019)
“... technologies for detection. Using RNAseq, we have identified a trypanosome specific small RNA to be present...”

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