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Inhibition of GSK-3 Ameliorates Ab Pathology in an Adult-Onset Drosophila Model of Alzheimer’s Disease

by Oyinkan Sofola, Fiona Kerr, Iain Rogers, Richard Killick, Hrvoje Augustin, Carina G
“... activity, and inhibition of GSK-3 (either genetically or pharmacologically by lithium treatment) rescued Ab...”

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Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease.

by Oyinkan Sofola, Fiona Kerr, Iain Rogers, Richard Killick, Hrvoje Augustin, Carina Gandy, Marcus J Allen, John Hardy, Simon Lovestone, Linda Partridge
Published in PLoS Genetics (2010)
“... in adult neurons increased GSK-3 activity, and inhibition of GSK-3 (either genetically or pharmacologically...”

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