Search Results

Large-scale whole-genome sequencing of the Icelandic population

by Gudbjartsson, Daniel F, Helgason, Hannes, Gudjonsson, Sigurjon A, Zink, Florian, Oddson, Asmundur, Gylfason, Arnaldur, Besenbacher, Soren, Magnusson, Gisli, Halldorsson, Bjarni V, Hjartarson, Eirikur, Sigurdsson, Gunnar Th, Stacey, Simon N, Frigge, Michael L, Holm, Hilma, Saemundsdottir, Jona, Helgadottir, Hafdis Th, Johannsdottir, Hrefna, Sigfusson, Gunnlaugur, Thorgeirsson, Gudmundur, Sverrisson, Jon Th, Gretarsdottir, Solveig, Walters, G Bragi, Rafnar, Thorunn, Thjodleifsson, Bjarni, Bjornsson, Einar S, Olafsson, Sigurdur, Thorarinsdottir, Hildur, Steingrimsdottir, Thora, Gudmundsdottir, Thora S, Theodors, Asgeir, Jonasson, Jon G, Sigurdsson, Asgeir, Bjornsdottir, Gyda, Jonsson, Jon J, Thorarensen, Olafur, Ludvigsson, Petur, Gudbjartsson, Hakon, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Arnar, David O, Magnusson, Olafur Th, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Sulem, Patrick, Stefansson, Kari
Published in Nature Genetics (2015)

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease.

by Nioi, Paul, Sigurdsson, Asgeir, Thorleifsson, Gudmar, Helgason, Hannes, Agustsdottir, Arna B, Norddahl, Gudmundur L, Helgadottir, Anna, Magnusdottir, Audur, Jonasdottir, Aslaug, Gretarsdottir, Solveig, Jonsdottir, Ingileif, Steinthorsdottir, Valgerdur, Rafnar, Thorunn, Swinkels, Dorine W, Galesloot, Tessel E, Grarup, Niels, Jørgensen, Torben, Vestergaard, Henrik, Hansen, Torben, Lauritzen, Torsten, Linneberg, Allan, Friedrich, Nele, Krarup, Nikolaj T, Fenger, Mogens, Abildgaard, Ulrik, Hansen, Peter R, Galløe, Anders M, Braund, Peter S, Nelson, Christopher P, Hall, Alistair S, Williams, Michael J A, van Rij, Andre M, Jones, Gregory T, Patel, Riyaz S, Levey, Allan I, Hayek, Salim, Shah, Svati H, Reilly, Muredach, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Kiemeney, Lambertus A, Quyyumi, Arshed A, Rader, Daniel J, Kraus, William E, Samani, Nilesh J, Pedersen, Oluf, Thorgeirsson, Gudmundur, Masson, Gisli, Holm, Hilma
Published in New England Journal of Medicine (2016)

Large-scale whole-genome sequencing of the Icelandic population.

by Gudbjartsson, Daniel F, Helgason, Hannes, Gudjonsson, Sigurjon A, Zink, Florian, Oddson, Asmundur, Gylfason, Arnaldur, Besenbacher, Soren, Magnusson, Gisli, Halldorsson, Bjarni V, Hjartarson, Eirikur, Sigurdsson, Gunnar Th, Stacey, Simon N, Frigge, Michael L, Holm, Hilma, Saemundsdottir, Jona, Helgadottir, Hafdis Th, Johannsdottir, Hrefna, Sigfusson, Gunnlaugur, Thorgeirsson, Gudmundur, Sverrisson, Jon Th, Gretarsdottir, Solveig, Walters, G Bragi, Rafnar, Thorunn, Thjodleifsson, Bjarni, Bjornsson, Einar S, Olafsson, Sigurdur, Thorarinsdottir, Hildur, Steingrimsdottir, Thora, Gudmundsdottir, Thora S, Theodors, Asgeir, Jonasson, Jon G, Sigurdsson, Asgeir, Bjornsdottir, Gyda, Jonsson, Jon J, Thorarensen, Olafur, Ludvigsson, Petur, Gudbjartsson, Hakon, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Arnar, David O, Magnusson, Olafur Th, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Sulem, Patrick, Stefansson, Kari
Published in Nature Genetics (2015)

Sequence variants from whole genome sequencing a large group of Icelanders

by Gudbjartsson, Daniel F, Sulem, Patrick, Helgason, Hannes, Gylfason, Arnaldur, Gudjonsson, Sigurjon A, Zink, Florian, Oddson, Asmundur, Magnusson, Gisli, Halldorsson, Bjarni V, Hjartarson, Eirikur, Sigurdsson, Gunnar Th., Kong, Augustine, Helgason, Agnar, Masson, Gisli, Magnusson, Olafur Th., Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Scientific Data (2015)

Parental influence on human germline de novo mutations in 1,548 trios from Iceland

by Jónsson, Hákon, Sulem, Patrick, Kehr, Birte, Kristmundsdottir, Snaedis, Zink, Florian, Hjartarson, Eirikur, Hardarson, Marteinn T., Hjorleifsson, Kristjan E., Eggertsson, Hannes P., Gudjonsson, Sigurjon Axel, Ward, Lucas D., Arnadottir, Gudny A., Helgason, Einar A., Helgason, Hannes, Gylfason, Arnaldur, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Rafnar, Thorunn, Frigge, Mike, Stacey, Simon N., Th. Magnusson, Olafur, Thorsteinsdottir, Unnur, Masson, Gisli, Kong, Augustine, Halldorsson, Bjarni V., Helgason, Agnar, Gudbjartsson, Daniel F., Stefansson, Kari
Published in Nature (2017)

Physical and neuro-behavioural determinants of reproductive onset and success

by Day, Felix R., Helgason, Hannes, Chasman, Daniel I., Rose, Lynda M., Loh, Po-Ru, Scott, Robert A., Helgason, Agnar, Kong, Augustine, Masson, Gisli, Magnusson, Olafur Th., Gudbjartsson, Daniel, Thorsteinsdottir, Unnur, Buring, Julie E., Ridker, Paul M., Sulem, Patrick, Stefansson, Kari, Ong, Ken K., Perry, John R.B.
Published in Nature Genetics (2016)

A common variant at 8q24.21 is associated with renal cell cancer.

by Gudmundsson, Julius, Sulem, Patrick, Gudbjartsson, Daniel F, Masson, Gisli, Petursdottir, Vigdis, Hardarson, Sverrir, Gudjonsson, Sigurjon A, Johannsdottir, Hrefna, Helgadottir, Hafdis Th, Stacey, Simon N, Magnusson, Olafur Th, Helgason, Hannes, Panadero, Angeles, van der Zanden, Loes F, Aben, Katja K H, Vermeulen, Sita H, Oosterwijk, Egbert, Kong, Augustine, Mayordomo, Jose I, Sverrisdottir, Asgerdur, Jonsson, Eirikur, Gudbjartsson, Tomas, Einarsson, Gudmundur V, Kiemeney, Lambertus A, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Nature Communications (2014)

Common and rare variants associated with kidney stones and biochemical traits.

by Oddsson, Asmundur, Sulem, Patrick, Helgason, Hannes, Edvardsson, Vidar O, Thorleifsson, Gudmar, Sveinbjörnsson, Gardar, Haraldsdottir, Eik, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Masson, Gisli, Holm, Hilma, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Indridason, Olafur S, Palsson, Runolfur, Stefansson, Kari
Published in Nature Communications (2015)

Association of BRCA2 K3326* With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin

by Rafnar, Thorunn, Sigurjonsdottir, Gudbjorg R, Stacey, Simon N, Halldorsson, Gisli, Sulem, Patrick, Pardo, Luba M, Helgason, Hannes, Sigurdsson, Stefan T, Gudjonsson, Thorkell, Tryggvadottir, Laufey, Olafsdottir, Gudridur H, Jonasson, Jon G, Alexiusdottir, Kristin, Sigurdsson, Asgeir, Gudmundsson, Julius, Saemundsdottir, Jona, Sigurdsson, Jon K, Johannsdottir, Hrefna, Uitterlinden, Andre, Vermeulen, Sita H, Galesloot, Tessel E, Allain, Dawn C, Lacko, Martin, Sigurgeirsson, Bardur, Thorisdottir, Kristin, Johannsson, Oskar T, Sigurdsson, Fridbjorn, Ragnarsson, Gunnar B, Isaksson, Helgi, Hardardottir, Hronn, Gudbjartsson, Tomas, Gudbjartsson, Daniel F, Masson, Gisli, Kiemeney, Lambertus A M L, Ewart Toland, Amanda, Nijsten, Tamar, Peters, Wilbert H M, Olafsson, Jon H, Jonsson, Steinn, Thorsteinsdottir, Unnur, Thorleifsson, Gudmar, Stefansson, Kari
Published in JNCI: Journal of the National Cancer Institute (2018)

Rate of de novo mutations and the importance of father's age to disease risk.

by Kong, Augustine, Frigge, Michael L, Masson, Gisli, Besenbacher, Soren, Sulem, Patrick, Magnusson, Gisli, Gudjonsson, Sigurjon A, Sigurdsson, Asgeir, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Wong, Wendy S W, Sigurdsson, Gunnar, Walters, G Bragi, Steinberg, Stacy, Helgason, Hannes, Thorleifsson, Gudmar, Gudbjartsson, Daniel F, Helgason, Agnar, Magnusson, Olafur Th, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature (2013)

A rare nonsynonymous sequence variant in C3 is associated with high risk of age-related macular degeneration.

by Helgason, Hannes, Sulem, Patrick, Duvvari, Maheswara R, Luo, Hongrong, Thorleifsson, Gudmar, Stefansson, Hreinn, Jonsdottir, Ingileif, Masson, Gisli, Gudbjartsson, Daniel F, Walters, G Bragi, Magnusson, Olafur Th, Kong, Augustine, Rafnar, Thorunn, Kiemeney, Lambertus A, Schoenmaker-Koller, Frederieke E, Zhao, Ling, Boon, Camiel J F, Song, Yaojun, Fauser, Sascha, Pei, Michelle, Ristau, Tina, Patel, Shirrina, Liakopoulos, Sandra, van de Ven, Johannes P H, Hoyng, Carel B, Ferreyra, Henry, Duan, Yaou, Bernstein, Paul S, Geirsdottir, Asbjorg, Helgadottir, Gudleif, Stefansson, Einar, den Hollander, Anneke I, Zhang, Kang, Jonasson, Fridbert, Sigurdsson, Haraldur, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2013)

Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer.

by Rafnar, Thorunn, Sulem, Patrick, Thorleifsson, Gudmar, Vermeulen, Sita H, Helgason, Hannes, Saemundsdottir, Jona, Gudjonsson, Sigurjon A, Sigurdsson, Asgeir, Stacey, Simon N, Gudmundsson, Julius, Johannsdottir, Hrefna, Alexiusdottir, Kristin, Petursdottir, Vigdis, Nikulasson, Sigfus, Geirsson, Gudmundur, Jonsson, Thorvaldur, Aben, Katja K H, Grotenhuis, Anne J, Verhaegh, Gerald W, Dudek, Aleksandra M, Witjes, J Alfred, van der Heijden, Antoine G, Vrieling, Alina, Galesloot, Tessel E, De Juan, Ana, Panadero, Angeles, Rivera, Fernando, Hurst, Carolyn, Bishop, D Timothy, Sak, Sei C, Choudhury, Ananya, Teo, Mark T W, Arici, Cecilia, Carta, Angela, Toninelli, Elena, de Verdier, Petra, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, van der Keur, Kirstin A, Lurkin, Irene, Goossens, Mieke, Kellen, Eliane, Guarrera, Simonetta, Russo, Alessia, Critelli, Rossana, Sacerdote, Carlotta, Vineis, Paolo, Krucker, Clémentine, Zeegers, Maurice P
Published in Human Molecular Genetics (2014)

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes.

by Steinthorsdottir, Valgerdur, Thorleifsson, Gudmar, Sulem, Patrick, Helgason, Hannes, Grarup, Niels, Sigurdsson, Asgeir, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Magnusson, Olafur T, Gudjonsson, Sigurjon A, Justesen, Johanne M, Harder, Marie N, Jørgensen, Marit E, Christensen, Cramer, Brandslund, Ivan, Sandbæk, Annelli, Lauritzen, Torsten, Vestergaard, Henrik, Linneberg, Allan, Jørgensen, Torben, Hansen, Torben, Daneshpour, Maryam S, Fallah, Mohammad-Sadegh, Hreidarsson, Astradur B, Sigurdsson, Gunnar, Azizi, Fereidoun, Benediktsson, Rafn, Masson, Gisli, Helgason, Agnar, Kong, Augustine, Gudbjartsson, Daniel F, Pedersen, Oluf, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2014)

Association of BRCA2 K3326* With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin.

by Rafnar, Thorunn, Sigurjonsdottir, Gudbjorg R, Stacey, Simon N, Halldorsson, Gisli, Sulem, Patrick, Pardo, Luba M, Helgason, Hannes, Sigurdsson, Stefan T, Gudjonsson, Thorkell, Tryggvadottir, Laufey, Olafsdottir, Gudridur H, Jonasson, Jon G, Alexiusdottir, Kristin, Sigurdsson, Asgeir, Gudmundsson, Julius, Saemundsdottir, Jona, Sigurdsson, Jon K, Johannsdottir, Hrefna, Uitterlinden, Andre, Vermeulen, Sita H, Galesloot, Tessel E, Allain, Dawn C, Lacko, Martin, Sigurgeirsson, Bardur, Thorisdottir, Kristin, Johannsson, Oskar T, Sigurdsson, Fridbjorn, Ragnarsson, Gunnar B, Isaksson, Helgi, Hardardottir, Hronn, Gudbjartsson, Tomas, Gudbjartsson, Daniel F, Masson, Gisli, Kiemeney, Lambertus A M L, Ewart Toland, Amanda, Nijsten, Tamar, Peters, Wilbert H M, Olafsson, Jon H, Jonsson, Steinn, Thorsteinsdottir, Unnur, Thorleifsson, Gudmar, Stefansson, Kari
Published in JNCI: Journal of the National Cancer Institute (2018)

Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events

by Helgason, Hannes, Eiriksdottir, Thjodbjorg, Ulfarsson, Magnus O., Choudhary, Abhishek, Lund, Sigrun H., Ivarsdottir, Erna V., Hjorleifsson Eldjarn, Grimur, Einarsson, Gudmundur, Ferkingstad, Egil, Moore, Kristjan H.S., Honarpour, Narimon, Liu, Thomas, Wang, Huei, Hucko, Thomas, Sabatine, Marc S., Morrow, David A., Giugliano, Robert P., Ostrowski, Sisse Rye, Pedersen, Ole Birger, Bundgaard, Henning, Erikstrup, Christian, Arnar, David O., Thorgeirsson, Gudmundur, Masson, Gísli, Magnusson, Olafur Th, Saemundsdottir, Jona, Gretarsdottir, Solveig, Steinthorsdottir, Valgerdur, Thorleifsson, Gudmar, Helgadottir, Anna, Sulem, Patrick, Thorsteinsdottir, Unnur, Holm, Hilma, Gudbjartsson, Daniel, Stefansson, Kari
Published in JAMA (2023)

Large-scale plasma proteomics comparisons through genetics and disease associations

by Eldjarn, Grimur Hjorleifsson, Ferkingstad, Egil, Lund, Sigrun H., Helgason, Hannes, Magnusson, Olafur Th, Gunnarsdottir, Kristbjorg, Olafsdottir, Thorunn A., Halldorsson, Bjarni V., Olason, Pall I., Zink, Florian, Gudjonsson, Sigurjon A., Sveinbjornsson, Gardar, Magnusson, Magnus I., Helgason, Agnar, Oddsson, Asmundur, Halldorsson, Gisli H., Magnusson, Magnus K., Sævarsdóttir, Sædís, Eiriksdottir, Thjodbjorg, Masson, Gisli, Stefansson, Hreinn, Jonsdottir, Ingileif, Holm, Hilma, Rafnar, Thorunn, Melsted, Pall, Saemundsdottir, Jona, Norddahl, Gudmundur L., Thorleifsson, Gudmar, Ulfarsson, Magnus O., Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published in Nature (2023)

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma

by Smith, Dirk, Helgason, Hannes, Sulem, Patrick, Bjornsdottir, Unnur Steina, Lim, Ai Ching, Sveinbjornsson, Gardar, Hasegawa, Haruki, Brown, Michael, Ketchem, Randal R, Gavala, Monica, Garrett, Logan, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Magnusson, Olafur T, Eyjolfsson, Gudmundur I, Olafsson, Isleifur, Onundarson, Pall Torfi, Sigurdardottir, Olof, Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn Runar, Ludviksdottir, Dora, Boezen, H Marike, Heinzmann, Andrea, Krueger, Marcus, Porsbjerg, Celeste, Ahluwalia, Tarunveer S, Waage, Johannes, Backer, Vibeke, Deichmann, Klaus A, Koppelman, Gerard H, Bønnelykke, Klaus, Bisgaard, Hans, Masson, Gisli, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Johnston, James A, Jonsdottir, Ingileif, Stefansson, Kari
Published in PLOS Genetics (2017)

Variants at the Interleukin 1 Gene Locus and Pericarditis

by Thorolfsdottir, Rosa B., Jonsdottir, Andrea B., Sveinbjornsson, Gardar, Aegisdottir, Hildur M., Oddsson, Asmundur, Stefansson, Olafur A., Halldorsson, Gisli H., Saevarsdottir, Saedis, Thorleifsson, Gudmar, Stefansdottir, Lilja, Pedersen, Ole B., Sørensen, Erik, Ghouse, Jonas, Raja, Anna Axelsson, Zheng, Chaoqun, Silajdzija, Elvira, Rand, Søren Albertsen, Erikstrup, Christian, Ullum, Henrik, Mikkelsen, Christina, Banasik, Karina, Brunak, Søren, Ivarsdottir, Erna V., Sigurdsson, Asgeir, Beyter, Doruk, Sturluson, Arni, Einarsson, Hafsteinn, Tragante, Vinicius, Helgason, Hannes, Lund, Sigrun H., Halldorsson, Bjarni V., Sigurpalsdottir, Brynja D., Olafsson, Isleifur, Arnar, David O., Thorgeirsson, Gudmundur, Knowlton, Kirk U., Nadauld, Lincoln D., Gretarsdottir, Solveig, Helgadottir, Anna, Ostrowski, Sisse R., Gudbjartssson, Daniel F., Jonsdottir, Ingileif, Bundgaard, Henning, Holm, Hilma, Sulem, Patrick, Stefansson, Kari
Published in JAMA Cardiology (2024)

Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events

by Helgason, Hannes, Eiriksdottir, Thjodbjorg, Ulfarsson, Magnus O., Choudhary, Abhishek, Lund, Sigrun H., Ivarsdottir, Erna V., Hjorleifsson Eldjarn, Grimur, Einarsson, Gudmundur, Ferkingstad, Egil, Moore, Kristjan H.S., Honarpour, Narimon, Liu, Thomas, Wang, Huei, Hucko, Thomas, Sabatine, Marc S., Morrow, David A., Giugliano, Robert P., Ostrowski, Sisse Rye, Pedersen, Ole Birger, Bundgaard, Henning, Erikstrup, Christian, Arnar, David O., Thorgeirsson, Gudmundur, Masson, Gísli, Magnusson, Olafur Th, Saemundsdottir, Jona, Gretarsdottir, Solveig, Steinthorsdottir, Valgerdur, Thorleifsson, Gudmar, Helgadottir, Anna, Sulem, Patrick, Thorsteinsdottir, Unnur, Holm, Hilma, Gudbjartsson, Daniel, Stefansson, Kari
Published in JAMA (2023)

Variants at the Interleukin 1 Gene Locus and Pericarditis

by Thorolfsdottir, Rosa B., Jonsdottir, Andrea B., Sveinbjornsson, Gardar, Aegisdottir, Hildur M., Oddsson, Asmundur, Stefansson, Olafur A., Halldorsson, Gisli H., Saevarsdottir, Saedis, Thorleifsson, Gudmar, Stefansdottir, Lilja, Pedersen, Ole B., Sørensen, Erik, Ghouse, Jonas, Raja, Anna Axelsson, Zheng, Chaoqun, Silajdzija, Elvira, Rand, Søren Albertsen, Erikstrup, Christian, Ullum, Henrik, Mikkelsen, Christina, Banasik, Karina, Brunak, Søren, Ivarsdottir, Erna V., Sigurdsson, Asgeir, Beyter, Doruk, Sturluson, Arni, Einarsson, Hafsteinn, Tragante, Vinicius, Helgason, Hannes, Lund, Sigrun H., Halldorsson, Bjarni V., Sigurpalsdottir, Brynja D., Olafsson, Isleifur, Arnar, David O., Thorgeirsson, Gudmundur, Knowlton, Kirk U., Nadauld, Lincoln D., Gretarsdottir, Solveig, Helgadottir, Anna, Ostrowski, Sisse R., Gudbjartssson, Daniel F., Jonsdottir, Ingileif, Bundgaard, Henning, Holm, Hilma, Sulem, Patrick, Stefansson, Kari, Bay, Jakob, Boldsen, Jens K., Brodersen, Thorsten, Burgdorf, Kristoffer, Chalmer, Mona A., Didriksen, Maria, Dinh, Khoa M., Dowsett, Joseph, Feenstra, Bjarke, Geller, Frank, Gudbjartsson, Daniel, Hansen, Thomas F., Hindhede, Lotte, Hjalgrim, Henrik, Jacobsen, Rikke L., Jemec, Gregor, Jensen, Bitten A., Kaspersen, Katrine, Kjerulff, Bertram D., Kogelman, Lisette, Larsen, Margit A. H., Louloudis, Ioannis, Lundgaard, Agnete, Mikkelsen, Susan, Nissen, Ioanna, Nyegaard, Mette, Pedersen, Ole Birger, Henriksen, Alexander P., Rohde, Palle D., Rostgaard, Klaus, Schwinn, Michael, Stefánsson, Hreinn, Thorsteinsdóttir, Unnur, Thørner, Lise W., Topholm Bruun, Mie, Werge, Thomas, Westergaard, David
Published in JAMA Cardiology (2024)