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Footprint of positive selection in Treponema pallidum subsp. pallidum genome sequences suggests adaptive microevolution of the syphilis pathogen.

by Lorenzo Giacani, Sujay Chattopadhyay, Arturo Centurion-Lara, Brendan M Jeffrey, Hoavan T Le, Barbara J Molini, Sheila A Lukehart, Evgeni V Sokurenko, Daniel D Rockey
Published in PLoS Neglected Tropical Diseases (2012)

Fine analysis of genetic diversity of the tpr gene family among treponemal species, subspecies and strains.

by Arturo Centurion-Lara, Lorenzo Giacani, Charmie Godornes, Barbara J Molini, Tara Brinck Reid, Sheila A Lukehart
Published in PLoS Neglected Tropical Diseases (2013)

Treponema pallidum subsp. pallidum TP0136 protein is heterogeneous among isolates and binds cellular and plasma fibronectin via its NH2-terminal end.

by Wujian Ke, Barbara J Molini, Sheila A Lukehart, Lorenzo Giacani
Published in PLOS Neglected Tropical Diseases (2015)

Longitudinal TprK profiling of in vivo and in vitro-propagated Treponema pallidum subsp. pallidum reveals accumulation of antigenic variants in absence of immune pressure.

by Michelle J Lin, Austin M Haynes, Amin Addetia, Nicole A P Lieberman, Quynh Phung, Hong Xie, Tien V Nguyen, Barbara J Molini, Sheila A Lukehart, Lorenzo Giacani, Alexander L Greninger
Published in PLOS Neglected Tropical Diseases (2021)