Species differences: The dark matter of longevity genetics

• Main Author: Bahry, David
• Format: Conference Object
• Language: English
• Published: Zenodo 2022
• Subjects: senescence; ageing; comparative biogerontology; cancer; protein misfolding; long-lived species; obscurin; hyccin; Pacific; Finch; Austad; bowhead whale; Ocean quahog
• Online Access: https://doi.org/10.5281/zenodo.7080319

Mainstream genetics of ageing and longevity studies modest longevity interventions known from short-lived model organisms, such as caloric restriction or rapamycin in nematodes or mice; and the evolutionarily conserved, nutrient-sensing metabolic fine-tuning pathways involved, such as insulin-like s...