Data from: Testosterone in ancient hair from an extinct species
Testosterone is a key regulator in vertebrate development, physiology, and behaviour. Whereas technology allows extraction of a wealth of genetic information from extant as well as extinct species, complimentary information on steroid hormone levels may add a social, sexual, and environmental contex...
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ftzenodo:oai:zenodo.org:4993419 2024-09-15T18:29:52+00:00 Data from: Testosterone in ancient hair from an extinct species Koren, Lee Matas, Devorah Pečnerová, Patrícia Dalén, Love Tikhonov, Alexei Gilbert, M. Thomas P. Wynne-Edwards, Katherine E. Geffen, Eli 2019-07-10 https://doi.org/10.5061/dryad.q951rb9 unknown Zenodo https://doi.org/10.1111/pala.12391 https://zenodo.org/communities/dryad https://doi.org/10.5061/dryad.q951rb9 oai:zenodo.org:4993419 info:eu-repo/semantics/openAccess Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode hair-testing testosterone endogenous steroids info:eu-repo/semantics/other 2019 ftzenodo https://doi.org/10.5061/dryad.q951rb910.1111/pala.12391 2024-07-26T07:45:35Z Testosterone is a key regulator in vertebrate development, physiology, and behaviour. Whereas technology allows extraction of a wealth of genetic information from extant as well as extinct species, complimentary information on steroid hormone levels may add a social, sexual, and environmental context. Hair shafts have been previously used to sequence DNA from >50,000 14C years old Siberian woolly mammoths (Mammuthus primigenius). Hair-testing has also been used to measure endogenous steroids in multiple extant species. Here we use small quantities of woolly mammoth hair samples to measure testosterone, and a genomics-based approach to determine sex, in permafrost-preserved mammoths dated to circa 10-60 thousand 14C years. Our validated method opens up exciting opportunities to measure multiple steroids in keratinized tissues from extinct populations of mammals. This may be specifically applied to investigating life histories, including the extinct Quaternary megafauna populations whose remains are preserved in the permafrost throughout the northern hemisphere. Supplementary electronic data Supplementary information describing LC-MS/MS conditions, blanks, and validations Other/Unknown Material permafrost Zenodo |
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hair-testing testosterone endogenous steroids |
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hair-testing testosterone endogenous steroids Koren, Lee Matas, Devorah Pečnerová, Patrícia Dalén, Love Tikhonov, Alexei Gilbert, M. Thomas P. Wynne-Edwards, Katherine E. Geffen, Eli Data from: Testosterone in ancient hair from an extinct species |
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hair-testing testosterone endogenous steroids |
description |
Testosterone is a key regulator in vertebrate development, physiology, and behaviour. Whereas technology allows extraction of a wealth of genetic information from extant as well as extinct species, complimentary information on steroid hormone levels may add a social, sexual, and environmental context. Hair shafts have been previously used to sequence DNA from >50,000 14C years old Siberian woolly mammoths (Mammuthus primigenius). Hair-testing has also been used to measure endogenous steroids in multiple extant species. Here we use small quantities of woolly mammoth hair samples to measure testosterone, and a genomics-based approach to determine sex, in permafrost-preserved mammoths dated to circa 10-60 thousand 14C years. Our validated method opens up exciting opportunities to measure multiple steroids in keratinized tissues from extinct populations of mammals. This may be specifically applied to investigating life histories, including the extinct Quaternary megafauna populations whose remains are preserved in the permafrost throughout the northern hemisphere. Supplementary electronic data Supplementary information describing LC-MS/MS conditions, blanks, and validations |
format |
Other/Unknown Material |
author |
Koren, Lee Matas, Devorah Pečnerová, Patrícia Dalén, Love Tikhonov, Alexei Gilbert, M. Thomas P. Wynne-Edwards, Katherine E. Geffen, Eli |
author_facet |
Koren, Lee Matas, Devorah Pečnerová, Patrícia Dalén, Love Tikhonov, Alexei Gilbert, M. Thomas P. Wynne-Edwards, Katherine E. Geffen, Eli |
author_sort |
Koren, Lee |
title |
Data from: Testosterone in ancient hair from an extinct species |
title_short |
Data from: Testosterone in ancient hair from an extinct species |
title_full |
Data from: Testosterone in ancient hair from an extinct species |
title_fullStr |
Data from: Testosterone in ancient hair from an extinct species |
title_full_unstemmed |
Data from: Testosterone in ancient hair from an extinct species |
title_sort |
data from: testosterone in ancient hair from an extinct species |
publisher |
Zenodo |
publishDate |
2019 |
url |
https://doi.org/10.5061/dryad.q951rb9 |
genre |
permafrost |
genre_facet |
permafrost |
op_relation |
https://doi.org/10.1111/pala.12391 https://zenodo.org/communities/dryad https://doi.org/10.5061/dryad.q951rb9 oai:zenodo.org:4993419 |
op_rights |
info:eu-repo/semantics/openAccess Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode |
op_doi |
https://doi.org/10.5061/dryad.q951rb910.1111/pala.12391 |
_version_ |
1810471347518701568 |