Data from: Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages
Brown and polar bears have become prominent examples in phylogeography, but previous phylogeographic studies relied largely on maternally inherited mitochondrial DNA (mtDNA) or were geographically restricted. The male-specific Y chromosome, a natural counterpart to mtDNA, has remained under-explored...
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ftzenodo:oai:zenodo.org:4987412 2024-09-15T18:40:16+00:00 Data from: Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages Bidon, Tobias Janke, Axel Fain, Steven R. Eiken, Hans Geir Hagen, Snorre B. Saarma, Urmas Hallström, Björn M. Lecomte, Nicolas Hailer, Frank 2015-03-19 https://doi.org/10.5061/dryad.3p21q unknown Zenodo https://doi.org/10.1093/molbev/msu109 https://zenodo.org/communities/dryad https://doi.org/10.5061/dryad.3p21q oai:zenodo.org:4987412 info:eu-repo/semantics/openAccess Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode STR Ursus arctos Y chromosome bear Ursus maritimus info:eu-repo/semantics/other 2015 ftzenodo https://doi.org/10.5061/dryad.3p21q10.1093/molbev/msu109 2024-07-26T11:11:57Z Brown and polar bears have become prominent examples in phylogeography, but previous phylogeographic studies relied largely on maternally inherited mitochondrial DNA (mtDNA) or were geographically restricted. The male-specific Y chromosome, a natural counterpart to mtDNA, has remained under-explored. Although this paternally inherited chromosome is indispensable for comprehensive analyses of phylogeographic patterns, technical difficulties and low variability have hampered its application in most mammals. We developed 13 novel Y-chromosomal sequence and microsatellite markers from the polar bear genome, and screened these in a broad geographic sample of 130 brown and polar bears. We also analyzed a 390 kb-long Y-chromosomal scaffold using sequencing data from published male ursine genomes. Y chromosome evidence support the emerging understanding that brown and polar bears started to diverge no later than the Middle Pleistocene. Contrary to mtDNA patterns, we found (i) brown and polar bears to be reciprocally monophyletic sister (or rather brother) lineages, without signals of introgression, (ii) male-biased gene flow across continents and on phylogeographic time scales, and (iii) male dispersal that links the Alaskan ABC-islands population to mainland brown bears. Due to female philopatry, mtDNA provides a highly structured estimate of population differentiation, while male-biased gene flow is a homogenizing force for nuclear genetic variation. Our findings highlight the importance of analyzing both maternally and paternally inherited loci for a comprehensive view of phylogeographic history, and that mtDNA-based phylogeographic studies of many mammals should be re-evaluated. Recent advances in sequencing technology render the analysis of Y chromosomal variation feasible, even in non-model organisms. Y STR Allele sizes A table of allele sizes of 9 Y STR markers from 134 individuals Submission DRYAD allele sizes.xlsx Other/Unknown Material Ursus arctos Ursus maritimus Zenodo |
institution |
Open Polar |
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op_collection_id |
ftzenodo |
language |
unknown |
topic |
STR Ursus arctos Y chromosome bear Ursus maritimus |
spellingShingle |
STR Ursus arctos Y chromosome bear Ursus maritimus Bidon, Tobias Janke, Axel Fain, Steven R. Eiken, Hans Geir Hagen, Snorre B. Saarma, Urmas Hallström, Björn M. Lecomte, Nicolas Hailer, Frank Data from: Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages |
topic_facet |
STR Ursus arctos Y chromosome bear Ursus maritimus |
description |
Brown and polar bears have become prominent examples in phylogeography, but previous phylogeographic studies relied largely on maternally inherited mitochondrial DNA (mtDNA) or were geographically restricted. The male-specific Y chromosome, a natural counterpart to mtDNA, has remained under-explored. Although this paternally inherited chromosome is indispensable for comprehensive analyses of phylogeographic patterns, technical difficulties and low variability have hampered its application in most mammals. We developed 13 novel Y-chromosomal sequence and microsatellite markers from the polar bear genome, and screened these in a broad geographic sample of 130 brown and polar bears. We also analyzed a 390 kb-long Y-chromosomal scaffold using sequencing data from published male ursine genomes. Y chromosome evidence support the emerging understanding that brown and polar bears started to diverge no later than the Middle Pleistocene. Contrary to mtDNA patterns, we found (i) brown and polar bears to be reciprocally monophyletic sister (or rather brother) lineages, without signals of introgression, (ii) male-biased gene flow across continents and on phylogeographic time scales, and (iii) male dispersal that links the Alaskan ABC-islands population to mainland brown bears. Due to female philopatry, mtDNA provides a highly structured estimate of population differentiation, while male-biased gene flow is a homogenizing force for nuclear genetic variation. Our findings highlight the importance of analyzing both maternally and paternally inherited loci for a comprehensive view of phylogeographic history, and that mtDNA-based phylogeographic studies of many mammals should be re-evaluated. Recent advances in sequencing technology render the analysis of Y chromosomal variation feasible, even in non-model organisms. Y STR Allele sizes A table of allele sizes of 9 Y STR markers from 134 individuals Submission DRYAD allele sizes.xlsx |
format |
Other/Unknown Material |
author |
Bidon, Tobias Janke, Axel Fain, Steven R. Eiken, Hans Geir Hagen, Snorre B. Saarma, Urmas Hallström, Björn M. Lecomte, Nicolas Hailer, Frank |
author_facet |
Bidon, Tobias Janke, Axel Fain, Steven R. Eiken, Hans Geir Hagen, Snorre B. Saarma, Urmas Hallström, Björn M. Lecomte, Nicolas Hailer, Frank |
author_sort |
Bidon, Tobias |
title |
Data from: Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages |
title_short |
Data from: Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages |
title_full |
Data from: Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages |
title_fullStr |
Data from: Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages |
title_full_unstemmed |
Data from: Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages |
title_sort |
data from: brown and polar bear y chromosomes reveal extensive male-biased gene flow within brother lineages |
publisher |
Zenodo |
publishDate |
2015 |
url |
https://doi.org/10.5061/dryad.3p21q |
genre |
Ursus arctos Ursus maritimus |
genre_facet |
Ursus arctos Ursus maritimus |
op_relation |
https://doi.org/10.1093/molbev/msu109 https://zenodo.org/communities/dryad https://doi.org/10.5061/dryad.3p21q oai:zenodo.org:4987412 |
op_rights |
info:eu-repo/semantics/openAccess Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode |
op_doi |
https://doi.org/10.5061/dryad.3p21q10.1093/molbev/msu109 |
_version_ |
1810484570108198912 |