Data from: Detecting genotypic changes associated with selective mortality at sea in Atlantic salmon: polygenic multi-locus analysis surpasses genome scan
Wild populations of Atlantic salmon have declined worldwide. While the causes for this decline may be complex and numerous, increased mortality at sea is predicted to be one of the major contributing factors. Examining the potential changes occurring in the genome-wide composition of populations dur...
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ftzenodo:oai:zenodo.org:4968067 2024-09-15T17:56:08+00:00 Data from: Detecting genotypic changes associated with selective mortality at sea in Atlantic salmon: polygenic multi-locus analysis surpasses genome scan Bourret, Vincent Dionne, Mélanie Bernatchez, Louis 2014-05-20 https://doi.org/10.5061/dryad.j86v9 unknown Zenodo https://doi.org/10.1111/mec.12798 https://zenodo.org/communities/dryad https://doi.org/10.5061/dryad.j86v9 oai:zenodo.org:4968067 info:eu-repo/semantics/openAccess Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode single nucleotide polymorphism Mortality at sea Salmo salar Contemporary Evolution info:eu-repo/semantics/other 2014 ftzenodo https://doi.org/10.5061/dryad.j86v910.1111/mec.12798 2024-07-26T06:57:27Z Wild populations of Atlantic salmon have declined worldwide. While the causes for this decline may be complex and numerous, increased mortality at sea is predicted to be one of the major contributing factors. Examining the potential changes occurring in the genome-wide composition of populations during this migration has the potential to tease apart some of the factors influencing marine mortality. Here, we genotyped 5568 SNPs in Atlantic salmon populations representing two distinct regional genetic groups and across two cohorts to test for differential allelic and genotypic frequencies between juveniles (smolts) migrating to sea and adults (grilses) returning to freshwater after one year at sea. Given the complexity of the traits potentially associated with sea mortality, we contrasted the outcomes of a single-locus FST based genome scan method with a new multi-locus framework to test for genetically-based differential mortality at sea. While numerous outliers were identified by the single-locus analysis, no evidence for parallel, temporally repeated selection was found. In contrast, the multi-locus approach detected repeated patterns of selection for a multi-locus group of 34 co-varying SNPs in one of the two populations. No significant pattern of selective mortality was detected in the other population, suggesting different causes of mortality among populations. These results first support the hypothesis that selection mainly causes small changes in allele frequencies among many co-varying loci rather than a small number of changes in loci with large effects. They also point out that moving away from the a strict "selective sweep paradigm" towards a multi-locus genetics framework may be a more useful approach for studying the genomic signatures of natural selection on complex traits in wild populations. Genotypes_PowerMarker Genotype file for 2923 SNPs retained for analyses performed in the article. Donnees_genet SAS 2923 Input file for SAS analyses SAS Discriminant Analysis SAS analyses Scripts ... Other/Unknown Material Atlantic salmon Salmo salar Zenodo |
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single nucleotide polymorphism Mortality at sea Salmo salar Contemporary Evolution |
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single nucleotide polymorphism Mortality at sea Salmo salar Contemporary Evolution Bourret, Vincent Dionne, Mélanie Bernatchez, Louis Data from: Detecting genotypic changes associated with selective mortality at sea in Atlantic salmon: polygenic multi-locus analysis surpasses genome scan |
topic_facet |
single nucleotide polymorphism Mortality at sea Salmo salar Contemporary Evolution |
description |
Wild populations of Atlantic salmon have declined worldwide. While the causes for this decline may be complex and numerous, increased mortality at sea is predicted to be one of the major contributing factors. Examining the potential changes occurring in the genome-wide composition of populations during this migration has the potential to tease apart some of the factors influencing marine mortality. Here, we genotyped 5568 SNPs in Atlantic salmon populations representing two distinct regional genetic groups and across two cohorts to test for differential allelic and genotypic frequencies between juveniles (smolts) migrating to sea and adults (grilses) returning to freshwater after one year at sea. Given the complexity of the traits potentially associated with sea mortality, we contrasted the outcomes of a single-locus FST based genome scan method with a new multi-locus framework to test for genetically-based differential mortality at sea. While numerous outliers were identified by the single-locus analysis, no evidence for parallel, temporally repeated selection was found. In contrast, the multi-locus approach detected repeated patterns of selection for a multi-locus group of 34 co-varying SNPs in one of the two populations. No significant pattern of selective mortality was detected in the other population, suggesting different causes of mortality among populations. These results first support the hypothesis that selection mainly causes small changes in allele frequencies among many co-varying loci rather than a small number of changes in loci with large effects. They also point out that moving away from the a strict "selective sweep paradigm" towards a multi-locus genetics framework may be a more useful approach for studying the genomic signatures of natural selection on complex traits in wild populations. Genotypes_PowerMarker Genotype file for 2923 SNPs retained for analyses performed in the article. Donnees_genet SAS 2923 Input file for SAS analyses SAS Discriminant Analysis SAS analyses Scripts ... |
format |
Other/Unknown Material |
author |
Bourret, Vincent Dionne, Mélanie Bernatchez, Louis |
author_facet |
Bourret, Vincent Dionne, Mélanie Bernatchez, Louis |
author_sort |
Bourret, Vincent |
title |
Data from: Detecting genotypic changes associated with selective mortality at sea in Atlantic salmon: polygenic multi-locus analysis surpasses genome scan |
title_short |
Data from: Detecting genotypic changes associated with selective mortality at sea in Atlantic salmon: polygenic multi-locus analysis surpasses genome scan |
title_full |
Data from: Detecting genotypic changes associated with selective mortality at sea in Atlantic salmon: polygenic multi-locus analysis surpasses genome scan |
title_fullStr |
Data from: Detecting genotypic changes associated with selective mortality at sea in Atlantic salmon: polygenic multi-locus analysis surpasses genome scan |
title_full_unstemmed |
Data from: Detecting genotypic changes associated with selective mortality at sea in Atlantic salmon: polygenic multi-locus analysis surpasses genome scan |
title_sort |
data from: detecting genotypic changes associated with selective mortality at sea in atlantic salmon: polygenic multi-locus analysis surpasses genome scan |
publisher |
Zenodo |
publishDate |
2014 |
url |
https://doi.org/10.5061/dryad.j86v9 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
https://doi.org/10.1111/mec.12798 https://zenodo.org/communities/dryad https://doi.org/10.5061/dryad.j86v9 oai:zenodo.org:4968067 |
op_rights |
info:eu-repo/semantics/openAccess Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode |
op_doi |
https://doi.org/10.5061/dryad.j86v910.1111/mec.12798 |
_version_ |
1810432344373329920 |