High temperature induces transcriptomic changes in Crassostrea gigas that hinder progress of ostreid herpes virus (OsHV-1) and promote survival
Of all environmental factors, seawater temperature plays a decisive role in triggering marine diseases. Like fever in vertebrates, high seawater temperature could modulate the host response to pathogens in ectothermic animals. In France, massive mortality of Pacific oysters, Crassostrea gigas , caus...
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ftzenodo:oai:zenodo.org:4069483 2024-09-15T18:03:09+00:00 High temperature induces transcriptomic changes in Crassostrea gigas that hinder progress of ostreid herpes virus (OsHV-1) and promote survival Delisle, Lizenn Pauletto, Marianna Vidal-Dupiol, Jeremie Petton, Bruno Bargelloni, Luca Montagnani, Caroline Pernet, Fabrice Corporeau, Charlotte Fleury, Elodie 2020-09-22 https://doi.org/10.5061/dryad.m37pvmcz0 unknown Zenodo https://doi.org/10.1016/j.fsi.2018.05.056 https://zenodo.org/communities/dryad https://doi.org/10.5061/dryad.m37pvmcz0 oai:zenodo.org:4069483 info:eu-repo/semantics/openAccess Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode info:eu-repo/semantics/other 2020 ftzenodo https://doi.org/10.5061/dryad.m37pvmcz010.1016/j.fsi.2018.05.056 2024-07-26T19:25:52Z Of all environmental factors, seawater temperature plays a decisive role in triggering marine diseases. Like fever in vertebrates, high seawater temperature could modulate the host response to pathogens in ectothermic animals. In France, massive mortality of Pacific oysters, Crassostrea gigas , caused by the ostreid herpesvirus 1 (OsHV-1) is markedly reduced when temperatures exceed 24°C in the field. In the present study we assess how high temperature influences the host response to the pathogen by comparing transcriptomes (RNA sequencing) during the course of experimental infection at 21°C (reference) and 29°C. We show that high temperature induced host physiological processes that are unfavorable to the viral infection. Temperature influenced the expression of transcripts related to the immune process and increased the transcription of genes related to the apoptotic process, synaptic signaling and protein processes at 29°C. Concomitantly, the expression of genes associated with catabolism, metabolite transport, macromolecule synthesis and cell growth remained low from the first stage of infection at 29°C. Moreover, viral entry into the host might have been limited at 29°C by changes in extracellular matrix composition and protein abundance. Overall, these results provide new insights into how environmental factors modulate host–pathogen interactions. Funding provided by: VIVALDI (H2020 program, n°678589) Crossref Funder Registry ID: Award Number: Funding provided by: French Ministry of Environment, Energy and Sea (Convention DPMA 2016 16/1212569) Crossref Funder Registry ID: Award Number: Other/Unknown Material Crassostrea gigas Zenodo |
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description |
Of all environmental factors, seawater temperature plays a decisive role in triggering marine diseases. Like fever in vertebrates, high seawater temperature could modulate the host response to pathogens in ectothermic animals. In France, massive mortality of Pacific oysters, Crassostrea gigas , caused by the ostreid herpesvirus 1 (OsHV-1) is markedly reduced when temperatures exceed 24°C in the field. In the present study we assess how high temperature influences the host response to the pathogen by comparing transcriptomes (RNA sequencing) during the course of experimental infection at 21°C (reference) and 29°C. We show that high temperature induced host physiological processes that are unfavorable to the viral infection. Temperature influenced the expression of transcripts related to the immune process and increased the transcription of genes related to the apoptotic process, synaptic signaling and protein processes at 29°C. Concomitantly, the expression of genes associated with catabolism, metabolite transport, macromolecule synthesis and cell growth remained low from the first stage of infection at 29°C. Moreover, viral entry into the host might have been limited at 29°C by changes in extracellular matrix composition and protein abundance. Overall, these results provide new insights into how environmental factors modulate host–pathogen interactions. Funding provided by: VIVALDI (H2020 program, n°678589) Crossref Funder Registry ID: Award Number: Funding provided by: French Ministry of Environment, Energy and Sea (Convention DPMA 2016 16/1212569) Crossref Funder Registry ID: Award Number: |
format |
Other/Unknown Material |
author |
Delisle, Lizenn Pauletto, Marianna Vidal-Dupiol, Jeremie Petton, Bruno Bargelloni, Luca Montagnani, Caroline Pernet, Fabrice Corporeau, Charlotte Fleury, Elodie |
spellingShingle |
Delisle, Lizenn Pauletto, Marianna Vidal-Dupiol, Jeremie Petton, Bruno Bargelloni, Luca Montagnani, Caroline Pernet, Fabrice Corporeau, Charlotte Fleury, Elodie High temperature induces transcriptomic changes in Crassostrea gigas that hinder progress of ostreid herpes virus (OsHV-1) and promote survival |
author_facet |
Delisle, Lizenn Pauletto, Marianna Vidal-Dupiol, Jeremie Petton, Bruno Bargelloni, Luca Montagnani, Caroline Pernet, Fabrice Corporeau, Charlotte Fleury, Elodie |
author_sort |
Delisle, Lizenn |
title |
High temperature induces transcriptomic changes in Crassostrea gigas that hinder progress of ostreid herpes virus (OsHV-1) and promote survival |
title_short |
High temperature induces transcriptomic changes in Crassostrea gigas that hinder progress of ostreid herpes virus (OsHV-1) and promote survival |
title_full |
High temperature induces transcriptomic changes in Crassostrea gigas that hinder progress of ostreid herpes virus (OsHV-1) and promote survival |
title_fullStr |
High temperature induces transcriptomic changes in Crassostrea gigas that hinder progress of ostreid herpes virus (OsHV-1) and promote survival |
title_full_unstemmed |
High temperature induces transcriptomic changes in Crassostrea gigas that hinder progress of ostreid herpes virus (OsHV-1) and promote survival |
title_sort |
high temperature induces transcriptomic changes in crassostrea gigas that hinder progress of ostreid herpes virus (oshv-1) and promote survival |
publisher |
Zenodo |
publishDate |
2020 |
url |
https://doi.org/10.5061/dryad.m37pvmcz0 |
genre |
Crassostrea gigas |
genre_facet |
Crassostrea gigas |
op_relation |
https://doi.org/10.1016/j.fsi.2018.05.056 https://zenodo.org/communities/dryad https://doi.org/10.5061/dryad.m37pvmcz0 oai:zenodo.org:4069483 |
op_rights |
info:eu-repo/semantics/openAccess Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode |
op_doi |
https://doi.org/10.5061/dryad.m37pvmcz010.1016/j.fsi.2018.05.056 |
_version_ |
1810440673543847936 |